Patents by Inventor Scott Eugene Lindner

Scott Eugene Lindner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11119054
    Abstract: Provided are processes and materials for solving biological or structural information about proteins or other organic molecules. The processes capitalize on a rigid multimeric nanocage formed from self-assembling substructure proteins. The processes and materials allow for recognition and tight, optionally covalent, bonding of any protein molecule with a tag complementary to a capture sequence on the nanocage. The processes and materials may be used to obtain biological or structural information by cryo-electron microscopy and overcome prior limitations of target protein size or salt concentration.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: September 14, 2021
    Assignee: THE PENN STATE RESEARCH FOUNDATION
    Inventors: Scott Eugene Lindner, Susan Hafenstein
  • Publication number: 20200124544
    Abstract: Provided are processes and materials for solving biological or structural information about proteins or other organic molecules. The processes capitalize on a rigid multimeric nanocage formed from self-assembling substructure proteins. The processes and materials allow for recognition and tight, optionally covalent, bonding of any protein molecule with a tag complementary to a capture sequence on the nanocage. The processes and materials may be used to obtain biological or structural information by cryo-electron microscopy and overcome prior limitations of target protein size or salt concentration.
    Type: Application
    Filed: March 16, 2018
    Publication date: April 23, 2020
    Inventors: Scott Eugene Lindner, Susan Hafenstein
  • Patent number: 9206439
    Abstract: The invention provides a recombinant vector comprising a DNA segment having a synthetic origin of DNA synthesis that binds EBNA-1 and is capable of initiating DNA synthesis of sequences linked to the synthetic origin of DNA synthesis and maintaining the linked sequences when in the presence of EBNA-1. The synthetic origin of DNA synthesis comprises at least two binding sites for EBNA-1, wherein the two EBNA-1 binding sites are flanked by at least two half-binding sites for TRF2 or at least two binding sites for a protein that enhances the affinity of EBNA-1 for the synthetic origin of DNA synthesis. Further provided are host cells with the vector and methods of using the vector, for instance, ex vivo or in vivo.
    Type: Grant
    Filed: January 14, 2009
    Date of Patent: December 8, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Scott Eugene Lindner, William M. Sugden
  • Publication number: 20090203545
    Abstract: The invention provides a recombinant vector comprising a DNA segment having a synthetic origin of DNA synthesis that binds EBNA-1 and is capable of initiating DNA synthesis of sequences linked to the synthetic origin of DNA synthesis and maintaining the linked sequences when in the presence of EBNA-1. The synthetic origin of DNA synthesis comprises at least two binding sites for EBNA-1, wherein the two EBNA-1 binding sites are flanked by at least two half-binding sites for TRF2 or at least two binding sites for a protein that enhances the affinity of EBNA-1 for the synthetic origin of DNA synthesis. Further provided are host cells with the vector and methods of using the vector, for instance, ex vivo or in vivo.
    Type: Application
    Filed: January 14, 2009
    Publication date: August 13, 2009
    Applicant: WARF-Wisconsin Alumni Research Foundation
    Inventors: Scott Eugene Lindner, William M. Sugden