Patents by Inventor Scott Franzblau

Scott Franzblau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic peptide from sp., process for the production thereof, and pharmaceutical composition for the prevention or treatment of mycobacteria related disease comprising the same
    Patent number: 9090667
    Abstract: The present invention relates to novel anti-TB cyclic peptides from Nonomuraea sp. MJM5123, a process for the production of the anti-Tuberculosis peptide and a pharmaceutical composition for the prevention and treatment of mycobacterial infection comprising the same. The composition of the present invention is highly active against replicating/non-replicating M. tuberculosis, including MDR and XDR strains, so that it can be effectively used as a therapeutic agent for tuberculosis.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: July 28, 2015
    Assignees: Myongji University Industry and Academia Cooperation Foundation, The Board of Trustees of the University of Illinois
    Inventors: Jong Woo Kim, Sang Wook Lee, Sang Jin Park, Joo Won Suh, In Ae Lee, Tae Mi Yoon, Jong Keun Choi, Ji Ean Lee, Jin Yong Kim, Ying Yu Jin, Scott Franzblau, Sanghyun Cho, Wei Gao, Guido Pauli, James McAlpine, Jose Napolitano, Birgit Jaki, Brent Friesen, Maria Florencia Rodriguez Brasco, David Lankin
  • CYCLIC PEPTIDE FROM NONOMURAEA SP., PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF MYCOBACTERIA RELATED DISEASE COMPRISING THE SAME
    Publication number: 20140142031
    Abstract: The present invention relates to novel anti-TB cyclic peptides from Nonomuraea sp. MJM5123, a process for the production of the anti-Tuberculosis peptide and a pharmaceutical composition for the prevention and treatment of mycobacterial infection comprising the same. The composition of the present invention is highly active against replicating/non-replicating M. tuberculosis, including MDR and XDR strains, so that it can be effectively used as a therapeutic agent for tuberculosis.
    Type: Application
    Filed: April 18, 2012
    Publication date: May 22, 2014
    Inventors: Jong Woo Kim, Sang Wook Lee, Sang jin Park, Joo Won Suh, In Ae Lee, Tae Mi Yoon, Jong Keun Choi, Ji Ean Lee, Jin Yong Kim, Ying Yu Jin, Scott Franzblau, Sanghyum Cho, Wei Gao, Guido Pauli, James McAlpine, Jose Napolitano, Birgit Jaki, Brent Friesen, Maria Florencia Rodriguez Brasco, David Lankin
  • Cationic substituted benzofurans as antimicrobial agents
    Publication number: 20080114047
    Abstract: A method of treating a Mycobacterium tuberculosis infection in a subject in need thereof by administering to the subject an effective amount of a cationic substituted benzofuran compound. Methods of treating microbial infections, including infections from protozoan pathogens, such as Leishmania donovani, Trypanosoma brucei rhodesiense, a Trypanosoma cruzi, and Plasmodium falciparum, and fungal pathogens, such as Candida albicans, Aspergillus fumigatus, and Cryptococcus neoformans, in a subject in need thereof by administering to the subject an effective amount of a cationic substituted benzofuran compound. Methods of synthesizing novel cationic substituted benzofuran compounds and the novel compounds themselves.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 15, 2008
    Inventors: Richard Tidwell, Karl Werbovetz, Scott Franzblau, Svetlana Bakunova, Stanislav Bakunov
  • Method of treating tuberculosis
    Publication number: 20060148730
    Abstract: Macrolide and ketolides, and compositions containing the same, useful in the treatment of tuberculosis are disclosed. Methods of treating tuberculosis using the macrolides and ketolides, and compositions containing the same, also are disclosed.
    Type: Application
    Filed: October 21, 2005
    Publication date: July 6, 2006
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Zhaohai Zhu, Scott Franzblau, Gengli Yu, Olga Krasnykh, Dahua Pan, Kanakeshwari Falzari, Baojie Wan, Saweon Hong, Huiwen Liu
  • Cationic substituted benzofurans as antimicrobial agents
    Publication number: 20050197378
    Abstract: A method of treating a Mycobacterium tuberculosis infection in a subject in need thereof by administering to the subject an effective amount of a cationic substituted benzofuran compound. Methods of treating microbial infections, including infections from protozoan pathogens, such as Leishmania donovani, Trypanosoma brucei rhodesiense, a Trypanosoma cruzi, and Plasmodium falciparum, and fungal pathogens, such as Candida albicans, Aspergillus fumigatus, and Cryptococcus neoformans, in a subject in need thereof by administering to the subject an effective amount of a cationic substituted benzofuran compound. Methods of synthesizing novel cationic substituted benzofuran compounds and the novel compounds themselves.
    Type: Application
    Filed: December 6, 2004
    Publication date: September 8, 2005
    Inventors: Richard Tidwell, Karl Werbovetz, Scott Franzblau, Svetlana Bakunova, Stanislav Bakunov
  • Method of treating tuberculosis
    Publication number: 20050014706
    Abstract: Macrolide and ketolides, and compositions containing the same, useful in the treatment of tuberculosis are disclosed. Methods of treating tuberculosis using the macrolides and ketolides, and compositions containing the same, also are disclosed.
    Type: Application
    Filed: July 12, 2004
    Publication date: January 20, 2005
    Inventors: Kanakeshwari Falzari, Scott Franzblau, Zhaohai Zhu