Abstract: Provided herein are solid tumor antigen targets for chimeric receptors and chimeric inhibitory receptors, and methods of using the same, such as for the treatment of cancer.

Abstract: Provided herein are EMCN-specific antigen-binding domains, and chimeric proteins including the EMCN-specific antigen-binding. Also provided herein are cells, nucleic acids, vectors, compositions, and methods directed to proteins including the EMCN-specific antigen-binding domains.

Abstract: A wind-resistant umbrella including a canopy attached to an upper end of a pole member, flexible ribs, and multiple load sensitive connectors (LSCs) is provided. The flexible ribs flex inwardly at a wind speed of more than about 10 miles per hour (mph) to preclude wind from traveling under the canopy. The LSCs detachably couple an upper canopy section to a lower canopy section of the canopy. The upper canopy section partially overlaps the lower canopy section along the LSCs. Upon impact from a wind gust that exceeds a speed of more than about 20 mph, at least one of the LSCs detach to allow wind to flow freely through one or more vents created between the upper and lower canopy sections, while providing warnings to a user, and to preclude wind-induced tilting and lifting actions on the wind-resistant umbrella, thereby precluding dislodgment thereof from an anchoring location.

Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.

Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.

Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.

Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.

Abstract: A combination chair and backpack arrangement.

Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.

Abstract: A wind-resistant umbrella including a canopy attached to an upper end of a pole member, flexible ribs, and multiple load sensitive connectors (LSCs) is provided. The flexible ribs flex inwardly at a wind speed of more than about 10 miles per hour (mph) to preclude wind from traveling under the canopy. The LSCs detachably couple an upper canopy section to a lower canopy section of the canopy. The upper canopy section partially overlaps the lower canopy section along the LSCs. Upon impact from a wind gust that exceeds a speed of more than about 20 mph, at least one of the LSCs detach to allow wind to flow freely through one or more vents created between the upper and lower canopy sections, while providing warnings to a user, and to preclude wind-induced tilting and lifting actions on the wind-resistant umbrella, thereby precluding dislodgment thereof from an anchoring location.

Abstract: A chair comprising preferably including a seat frame coupled to a back frame; a seat panel coupled to the seat frame and a back support panel coupled to the back frame; a front leg frame coupled to a back leg frame; a first arm rest coupled at one end thereof to a first segment of the back frame; a second arm rest coupled at one end thereof to a second segment of the back frame; a front leg crossbar coupled between a first segment of the front leg frame and a second segment of the front leg frame; a rear leg crossbar coupled between a first segment of the back leg frame and a second segment of the back leg frame; and an assembly that permits a collapsing the chair from at least an open position to a collapsed position and flexing members that will flex during a rocking of the chair between at least one of a rearward and forward position to the other of the forward and rearward position.

Abstract: Provided herein are acute myeloid leukemia antigen targets for chimeric receptors and methods of using same.

Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.

Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.

Abstract: A collapsible cart assembly having a framework with two brackets. The two brackets have first arms, second arms and third arms. A rear leg frame section is rigidly affixed to the first arms. A front leg frame section that is pivotably connected to the second arms. A handle frame section is pivotably connected to the third arms of the brackets. Slides are disposed on the rear leg frame section. A first set of linkages connect the slides to the front leg frame section. A second set of linkages connect the slides to the handle frame section. The slides and linkages move the front leg frame the handle frame between an open configuration and a closed configuration.

Abstract: A folding chair assembly with an improved folding mechanism. The folding chair assembly has a backrest structure, a seat structure, and an armrest structure that are all made from shaped tube forms. The tube form of the armrest structure is attached to the tube form of the backrest structure with a pivot connection. The tube form of the armrest structure is also attached to the tube form of the seat structure at a pivot connection. A slotted linkage is provided that extends between the tube form of the backrest and the tube form of the seat. The slotted linkage is pivotably connected to either the backrest structure or to the seat structure. The slotted linkage defines a slot. The slot engages a fixed pin on either the seat structure or the backrest structure. The fixed pin reciprocally moves within the slot as the folding chair assembly is manipulated.

Abstract: A combination chair and backpack arrangement.

Abstract: A chair comprising preferably including a seat frame coupled to a back frame; a seat panel coupled to the seat frame and a back support panel coupled to the back frame; a front leg frame coupled to a back leg frame; a first arm rest coupled at one end thereof to a first segment of the back frame; a second arm rest coupled at one end thereof to a second segment of the back frame; a front leg crossbar coupled between a first segment of the front leg frame and a second segment of the front leg frame; a rear leg crossbar coupled between a first segment of the back leg frame and a second segment of the back leg frame; and an assembly that permits a collapsing the chair from at least an open position to a collapsed position and flexing members that will flex during a rocking of the chair between at least one of a rearward and forward position to the other of the forward and rearward position.

Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.

Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.