Patents by Inventor Scott Garrison

Scott Garrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250041345
    Abstract: Described herein are multicistronic expression systems that encode chimeric proteins, specifically membrane-cleavable chimeric systems and chimeric antigen receptors. Also described herein are nucleic acids, cells, and methods directed to the same.
    Type: Application
    Filed: October 21, 2024
    Publication date: February 6, 2025
    Inventors: Brian Scott Garrison, Michelle Elizabeth Hung, Nicholas Frankel, Han Deng, Gozde Yucel
  • Publication number: 20250032548
    Abstract: Provided herein are antibodies and antigen binding fragments thereof specific for endomucin (EMCN). Also provided herein are cells, nucleic acids, vectors, compositions, and methods directed to antibodies or antigen-binding domains thereof specific for EMCN.
    Type: Application
    Filed: October 18, 2024
    Publication date: January 30, 2025
    Inventors: Brian Scott Garrison, Michelle Elizabeth Hung
  • Publication number: 20240277765
    Abstract: Provided herein are acute myeloid leukemia antigen targets for chimeric receptors and methods of using same.
    Type: Application
    Filed: November 3, 2023
    Publication date: August 22, 2024
    Inventors: Brian Scott Garrison, Jennifer Chien, Kathryn Armstrong Loving, Russell Morrison Gordley, Michelle Elizabeth Hung
  • Patent number: 12005081
    Abstract: Provided herein are acute myeloid leukemia antigen targets for chimeric receptors and methods of using same.
    Type: Grant
    Filed: June 3, 2021
    Date of Patent: June 11, 2024
    Assignee: Senti Biosciences, Inc.
    Inventors: Brian Scott Garrison, Jennifer Chien, Kathryn Armstrong Loving, Russell Morrison Gordley, Michelle Elizabeth Hung
  • Publication number: 20240042027
    Abstract: Provided herein are solid tumor antigen targets for chimeric receptors and chimeric inhibitory receptors, and methods of using the same, such as for the treatment of cancer.
    Type: Application
    Filed: May 24, 2023
    Publication date: February 8, 2024
    Inventors: Brian Scott GARRISON, Alba GONZALEZ-JUNCA, Gary LEE, Assen Boyanov ROGUEV, Frances Deen LIU, Nicholas FRANKEL
  • Publication number: 20230372486
    Abstract: Provided herein are EMCN-specific antigen-binding domains, and chimeric proteins including the EMCN-specific antigen-binding. Also provided herein are cells, nucleic acids, vectors, compositions, and methods directed to proteins including the EMCN-specific antigen-binding domains.
    Type: Application
    Filed: April 14, 2023
    Publication date: November 23, 2023
    Inventors: Brian Scott GARRISON, Michelle Elizabeth HUNG, Nicholas FRANKEL
  • Publication number: 20230270789
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Application
    Filed: July 25, 2022
    Publication date: August 31, 2023
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang
  • Publication number: 20220378842
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Application
    Filed: June 23, 2022
    Publication date: December 1, 2022
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
  • Publication number: 20220378822
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Application
    Filed: August 28, 2020
    Publication date: December 1, 2022
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang
  • Patent number: 11446332
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: September 20, 2022
    Assignee: SENTI BIOSCIENCES, INC.
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang
  • Patent number: 11419898
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: August 23, 2022
    Assignee: SENTI BIOSCIENCES, INC.
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
  • Publication number: 20210299177
    Abstract: Provided herein are acute myeloid leukemia antigen targets for chimeric receptors and methods of using same.
    Type: Application
    Filed: June 3, 2021
    Publication date: September 30, 2021
    Inventors: Brian Scott Garrison, Jennifer Chien, Kathryn Armstrong Loving, Russell Morrison Gordley, Michelle Elizabeth Hung
  • Publication number: 20210228640
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Application
    Filed: March 31, 2021
    Publication date: July 29, 2021
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
  • Patent number: 10993967
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: May 4, 2021
    Assignee: SENTI BIOSCIENCES, INC.
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
  • Patent number: 10737712
    Abstract: A collapsible cart assembly having a framework with two brackets. The two brackets have first arms, second arms and third arms. A rear leg frame section is rigidly affixed to the first arms. A front leg frame section that is pivotably connected to the second arms. A handle frame section is pivotably connected to the third arms of the brackets. Slides are disposed on the rear leg frame section. A first set of linkages connect the slides to the front leg frame section. A second set of linkages connect the slides to the handle frame section. The slides and linkages move the front leg frame the handle frame between an open configuration and a closed configuration.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: August 11, 2020
    Assignee: Rio Brands, LLC
    Inventors: Scott Garrison, Xiang Shan Zhang
  • Publication number: 20200206271
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Application
    Filed: April 13, 2018
    Publication date: July 2, 2020
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca
  • Publication number: 20200171093
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
    Type: Application
    Filed: October 17, 2019
    Publication date: June 4, 2020
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
  • Patent number: 10610020
    Abstract: A folding chair assembly with an improved folding mechanism. The folding chair assembly has a backrest structure, a seat structure, and an armrest structure that are all made from shaped tube forms. The tube form of the armrest structure is attached to the tube form of the backrest structure with a pivot connection. The tube form of the armrest structure is also attached to the tube form of the seat structure at a pivot connection. A slotted linkage is provided that extends between the tube form of the backrest and the tube form of the seat. The slotted linkage is pivotably connected to either the backrest structure or to the seat structure. The slotted linkage defines a slot. The slot engages a fixed pin on either the seat structure or the backrest structure. The fixed pin reciprocally moves within the slot as the folding chair assembly is manipulated.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: April 7, 2020
    Assignee: Rio Brands, LLC
    Inventors: Scott Garrison, Kalman Fang
  • Publication number: 20200085876
    Abstract: Provided herein are methods and compositions for dynamically controlling and targeting multiple arms of the immune system. Some aspects provide mesenchymal stem cells (MSCs) engineered to produce multiple effector molecules. In some instances, each effector molecule modulates a different cell type of the immune system or different functions of a cell. Also provided herein are methods of using the MSCs to treat or alleviate symptoms of inflammatory bowel disease (IBD), for example.
    Type: Application
    Filed: March 16, 2018
    Publication date: March 19, 2020
    Inventors: Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee
  • Publication number: 20190338549
    Abstract: A collapsible stand that is designed for use on loose soil or sand. The collapsible stand has a central shaft and an auger that extends from the shaft. A slide hub moves along the central shaft between a first position and a second position. Legs radially extend from the central shaft. Linkages are used to interconnect the legs with the slide hub. When the slide hub moves to its first position along the central shaft, the linkages move the legs into a stowed configuration. When the slide hub moves to the second position, the linkages move the legs into a deployed configuration. The central shaft is set into the ground using the auger. The legs are deployed, wherein the legs have footpads that rest upon the ground. The pull of the auger biases the footpads against the ground and create a highly stable stand.
    Type: Application
    Filed: April 30, 2019
    Publication date: November 7, 2019
    Inventors: Jason McDermott, Scott Garrison