Patents by Inventor Scott Hammond

Scott Hammond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12001965
    Abstract: The present disclosure relates to techniques for developing artificial intelligence algorithms by distributing analytics to multiple sources of privacy protected, harmonized data. Particularly, aspects are directed to a computer implemented method that includes receiving an algorithm and input data requirements associated with the algorithm, identifying data assets as being available from a data host based on the input data requirements, curating the data assets within a data storage structure that is within infrastructure of the data host, and integrating the algorithm into a secure capsule computing framework. The secure capsule computing framework serves the algorithm to the data assets within the data storage structure in a secure manner that preserves privacy of the data assets and the algorithm. The computer implemented method further includes running the data assets through the algorithm to obtain an inference.
    Type: Grant
    Filed: June 14, 2023
    Date of Patent: June 4, 2024
    Assignee: The Regents of the University of California
    Inventors: Rachael A. Callcut, Michael Blum, Joe Hesse, Robert D. Rogers, Scott Hammond, Mary Elizabeth Chalk
  • Patent number: 11939382
    Abstract: The disclosure relates to binding proteins, including antibodies, that bind to Programmed Death-1 (“PD-1”) and T cell immunoreceptor with Ig and ITIM domains (“TIGIT”). The disclosure also provides compositions comprising such binding proteins and nucleic acid molecules encoding such binding proteins. The disclosure further relates to methods of treating a disorder or condition using such binding proteins.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: March 26, 2024
    Assignee: MedImmune, LLC
    Inventors: Yariv Mazor, Yue Wang, Gordon Moody, Deepali Malhotra, Michael Overstreet, Eleanor Clancy-Thompson, Karin Lee, Stacy Pryts, Scott Hammond
  • Publication number: 20240094776
    Abstract: Methods, systems, and devices for providing computer implemented services are disclosed. To provide the computer implemented services, the quantity of hardware resources available for providing the computer implemented services may be modified. The quantity of hardware resources may be modified by adding removable cards to a host system. When the removable card is added, a removable attachment element may be used to secure the removable card in place and maintain operable connection between the host system and the removable card.
    Type: Application
    Filed: September 20, 2022
    Publication date: March 21, 2024
    Inventors: Mark Hammond, James Frederic McKinney, Scott Elvin Johnson, Karl Isaac Hamand
  • Publication number: 20240075160
    Abstract: Provided herein are methods of treating cancer in a human subject, comprising administering to the subject: i) an antibody-drug conjugate (ADC) comprising an antibody, a cleavable linker and a cytotoxic agent, and ii) a bispecific checkpoint inhibitor. Further provided herein are kits comprising i) an antibody-drug conjugate (ADC) comprising an antibody, a cleavable linker and a cytotoxic agent, and ii) a bispecific checkpoint inhibitor.
    Type: Application
    Filed: July 27, 2023
    Publication date: March 7, 2024
    Inventors: Bilal OMAR, Scott A. HAMMOND, Judith ANDERTON, Nadia LUHESHI, Daniel J. FREEMAN, Krista KINNEER, Jorge ZERON-MEDINA CUAIRAN, Ikbel ACHOUR, Doug PALMER
  • Publication number: 20230340152
    Abstract: The present disclosure provides anti-CD73 binding molecules, e.g., antibodies and antigen binding fragments thereof. Also provided are pharmaceutical formulations comprising the disclosed compositions, and methods for the diagnosis and treatment of diseases associated with CD73-expression, e.g., cancer. Such diseases can be treated, e.g., by direct therapy with the anti-CD73 binding molecules disclosed herein (e.g., naked antibodies or antibody-drug conjugates that bind CD73), by adjuvant therapy with other antigen-binding anticancer agents such as immune checkpoint inhibitors (e.g., anti-CTLA-4 and anti-PD-1 monoclonal antibodies), and/or by combination therapies where the anti-CD73 molecules are administered before, after, or concurrently with chemotherapy.
    Type: Application
    Filed: November 30, 2022
    Publication date: October 26, 2023
    Inventors: Carl HAY, Kris SACHSENMEIER, Erin SULT, Qihui Huang, Peter PAVLIK, Melissa DAMSCHRODER, Li CHENG, Gundo DIEDRICH, Jonathan RIOS-DORIA, Scott HAMMOND, Ralph MINTER, Steve RUST, Sandrine GUILLARD, Robert HOLLINGSWORTH, Lutz JERMUTUS, Nicholas DURHAM, Ching Ching LEOW, Mary ANTONYSAMY, James GEOGHEGAN, Xiaojun LU, Kim ROSENTHAL
  • Publication number: 20230325682
    Abstract: The present disclosure relates to techniques for developing artificial intelligence algorithms by distributing analytics to multiple sources of privacy protected, harmonized data. Particularly, aspects are directed to a computer implemented method that includes receiving an algorithm and input data requirements associated with the algorithm, identifying data assets as being available from a data host based on the input data requirements, curating the data assets within a data storage structure that is within infrastructure of the data host, and integrating the algorithm into a secure capsule computing framework. The secure capsule computing framework serves the algorithm to the data assets within the data storage structure in a secure manner that preserves privacy of the data assets and the algorithm. The computer implemented method further includes running the data assets through the algorithm to obtain an inference.
    Type: Application
    Filed: June 14, 2023
    Publication date: October 12, 2023
    Applicant: The Regents of the University of California
    Inventors: Rachael A. Callcut, Michael Blum, Joe Hesse, Robert D. Rogers, Scott Hammond, Mary Elizabeth Chalk
  • Patent number: 11748633
    Abstract: The present disclosure relates to techniques for developing artificial intelligence algorithms by distributing analytics to multiple sources of privacy protected, harmonized data. Particularly, aspects are directed to a computer implemented method that includes receiving an algorithm and input data requirements associated with the algorithm, identifying data assets as being available from a data host based on the input data requirements, curating the data assets within a data storage structure that is within infrastructure of the data host, and integrating the algorithm into a secure capsule computing framework. The secure capsule computing framework serves the algorithm to the data assets within the data storage structure in a secure manner that preserves privacy of the data assets and the algorithm. The computer implemented method further includes running the data assets through the algorithm to obtain an inference.
    Type: Grant
    Filed: November 16, 2022
    Date of Patent: September 5, 2023
    Assignee: The Regents of the University of California
    Inventors: Rachael A. Callcut, Michael Blum, Joe Hesse, Robert D. Rogers, Scott Hammond, Mary Elizabeth Chalk
  • Patent number: 11717482
    Abstract: The present invention relates in part to novel drug delivery particles comprising an anionic polymer matrix and a cationic polymer, wherein the anionic polymer matrix and cationic polymer together form drug delivery particles bound by electrostatic interactions and wherein the drug delivery particles comprise at least one biologically active agent. The invention also relates in part to a method of treating a mycobacterial infection using said drug delivery particles, and a method of making said drug delivery particles.
    Type: Grant
    Filed: August 30, 2022
    Date of Patent: August 8, 2023
    Assignee: The Penn State Research Foundation
    Inventors: Scott Hammond Medina, Andrew William Simonson
  • Publication number: 20230235062
    Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.
    Type: Application
    Filed: November 1, 2022
    Publication date: July 27, 2023
    Inventors: CHRISTOPHE QUEVA, MICHELLE MORROW, SCOTT HAMMOND, MARAT ALIMZHANOV, JOHN BABCOOK, IAN FOLTZ, JASPAL SINGH KANG, LAURA SEKIROV, MELANIE BOYLE, MATTHIEU CHODORGE, ROSS A. STEWART, KATHLEEN ANN MULGREW
  • Publication number: 20230080780
    Abstract: The present disclosure relates to techniques for developing artificial intelligence algorithms by distributing analytics to multiple sources of privacy protected, harmonized data. Particularly, aspects are directed to a computer implemented method that includes receiving an algorithm and input data requirements associated with the algorithm, identifying data assets as being available from a data host based on the input data requirements, curating the data assets within a data storage structure that is within infrastructure of the data host, and integrating the algorithm into a secure capsule computing framework. The secure capsule computing framework serves the algorithm to the data assets within the data storage structure in a secure manner that preserves privacy of the data assets and the algorithm. The computer implemented method further includes running the data assets through the algorithm to obtain an inference.
    Type: Application
    Filed: November 16, 2022
    Publication date: March 16, 2023
    Applicant: The Regents of the University of California
    Inventors: Rachael A. Callcut, Michael Blum, Joe Hesse, Robert D. Rogers, Scott Hammond, Mary Elizabeth Chalk
  • Patent number: 11571454
    Abstract: Provided is a method for treating cancer by administering to an individual who has the cancer a MAD1 peptide. The peptide can enhance the effect of a chemotherapeutic agent that is administered to the individual in combination with the peptide.
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: February 7, 2023
    Assignee: The Penn State Research Foundation
    Inventors: Scott Hammond Medina, Andrew William Simonson, Matthew Aronson
  • Publication number: 20220409542
    Abstract: The present invention relates in part to novel drug delivery particles comprising an anionic polymer matrix and a cationic polymer, wherein the anionic polymer matrix and cationic polymer together form drug delivery particles bound by electrostatic interactions and wherein the drug delivery particles comprise at least one biologically active agent. The invention also relates in part to a method of treating a mycobacterial infection using said drug delivery particles, and a method of making said drug delivery particles.
    Type: Application
    Filed: August 30, 2022
    Publication date: December 29, 2022
    Inventors: Scott Hammond Medina, Andrew William Simonson
  • Publication number: 20220411509
    Abstract: The disclosure relates to binding proteins, including antibodies, that bind to Programmed Death-1 (“PD-1”) and T cell immunoreceptor with Ig and ITIM domains (“TIGIT”). The disclosure also provides compositions comprising such binding proteins and nucleic acid molecules encoding such binding proteins. The disclosure further relates to methods of treating a disorder or condition using such binding proteins.
    Type: Application
    Filed: April 29, 2022
    Publication date: December 29, 2022
    Applicant: MedImmune, LLC
    Inventors: Yariv MAZOR, Yue WANG, Gordon MOODY, Deepali MALHOTRA, Michael OVERSTREET, Eleanor CLANCY-THOMPSON, Karin LEE, Stacy PRYTS, Scott HAMMOND
  • Patent number: 11531904
    Abstract: The present disclosure relates to techniques for developing artificial intelligence algorithms by distributing analytics to multiple sources of privacy protected, harmonized data. Particularly, aspects are directed to a computer implemented method that includes receiving an algorithm and input data requirements associated with the algorithm, identifying data assets as being available from a data host based on the input data requirements, curating the data assets within a data storage structure that is within infrastructure of the data host, and integrating the algorithm into a secure capsule computing framework. The secure capsule computing framework serves the algorithm to the data assets within the data storage structure in a secure manner that preserves privacy of the data assets and the algorithm. The computer implemented method further includes running the data assets through the algorithm to obtain an inference.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: December 20, 2022
    Assignee: The Regents of the University of California
    Inventors: Rachael Callcut, Michael Blum, Joe Hesse, Robert D. Rogers, Scott Hammond, Mary Elizabeth Chalk
  • Patent number: 11525012
    Abstract: The present disclosure provides anti-CD73 binding molecules, e.g., antibodies and antigen binding fragments thereof. Also provided are pharmaceutical formulations comprising the disclosed compositions, and methods for the diagnosis and treatment of diseases associated with CD73-expression, e.g., cancer. Such diseases can be treated, e.g., by direct therapy with the anti-CD73 binding molecules disclosed herein (e.g., naked antibodies or antibody-drug conjugates that bind CD73), by adjuvant therapy with other antigen-binding anticancer agents such as immune checkpoint inhibitors (e.g., anti-CTLA-4 and anti-PD-1 monoclonal antibodies), and/or by combination therapies where the anti-CD73 molecules are administered before, after, or concurrently with chemotherapy.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: December 13, 2022
    Assignee: MedImmune Limited
    Inventors: Carl Hay, Kris Sachsenmeier, Erin Sult, Qihui Huang, Peter Pavlik, Melissa Damschroder, Li Cheng, Gundo Diedrich, Jonathan Rios-Doria, Scott Hammond, Ralph Minter, Steve Rust, Sandrine Guillard, Robert Hollingsworth, Lutz Jermutus, Nicholas Durham, Ching Ching Leow, Mary Antonysamy, James Geoghegan, Xiaojun Lu, Kim Rosenthal
  • Patent number: 11518809
    Abstract: Human monoclonal antibodies directed against B7-H1 and uses of these antibodies in diagnostics and for the treatment of diseases associated with the activity and/or expression of B7-H1 are disclosed. Additionally, hybridomas or other cell lines expressing such antibodies are disclosed.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: December 6, 2022
    Assignee: MEDIMMUNE LIMITED
    Inventors: Christophe Queva, Michelle Morrow, Scott Hammond, Marat Alimzhanov, John Babcock, Ian Foltz, Jaspal Singh Kang, Laura Sekirov, Melanie Boyle, Matthieu Chodorge, Ross A. Stewart, Kathleen Ann Mulgrew
  • Publication number: 20220332818
    Abstract: The present disclosure provides methods of altering engagement between T-cell immunoglobulin and mucin domain containing protein-3 (TIM-3) and phosphatidylserine (PS) in a subject. Also provided are methods of treatment using TIM-3 binding protein wherein the TIM-3 binding domain specifically binds to the C?C? and DE loops of the immunoglobulin variable (IgV) domain of TIM-3.
    Type: Application
    Filed: April 12, 2022
    Publication date: October 20, 2022
    Inventors: Kristen POLLIZZI, Scott A. HAMMOND, Yariv MAZOR, Trinity PERRY, Stacy PRYTS, Ashvin R. JAISWAL, Vaheh OGANSEYAN, Chunning YANG, Raffael KUREK, Natalia CEAICOVSCAIA, Charles FERTE, Eleanor CLANCY-THOMPSON
  • Patent number: 11458099
    Abstract: The present invention relates in part to novel drug delivery particles comprising an anionic polymer matrix and a cationic polymer, wherein the anionic polymer matrix and cationic polymer together form drug delivery particles bound by electrostatic interactions and wherein the drug delivery particles comprise at least one biologically active agent. The invention also relates in part to a method of treating a mycobacterial infection using said drug delivery particles, and a method of making said drug delivery particles.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: October 4, 2022
    Assignee: The Penn State Research Foundation
    Inventors: Scott Hammond Medina, Andrew William Simonson
  • Publication number: 20220251204
    Abstract: The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making such proteins. The disclosure provides methods of inducing an immune response in a subject as well as methods for treating or preventing cancer in a subject by administering the proteins, nucleic acid molecules and/or compositions to the subject.
    Type: Application
    Filed: December 14, 2021
    Publication date: August 11, 2022
    Inventors: Srinath KASTURIRANGAN, Changshou GAO, Godfrey RAINEY, Michelle MORROW, Claire Louise DOBSON, Stacey DRABIC, Darren SCHOFIELD, Gianluca CARLESSO, Kristen POLLIZZI, Yariv MAZOR, Michael OBERST, Scott A. HAMMOND, Brian LOBO, Prakash MANIKWAR, Jonathan SEAMAN, Simon DOVEDI, Ronald HERBST
  • Patent number: RE49908
    Abstract: The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making such proteins. The disclosure provides methods of inducing an immune response in a subject as well as methods for treating or preventing cancer in a subject by administering the proteins, nucleic acid molecules and/or compositions to the subject.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: April 9, 2024
    Assignee: MedImmune, LLC
    Inventors: Srinath Kasturirangan, Changshou Gao, Godfrey Rainey, Michelle Morrow, Claire Louise Dobson, Stacey Drabic, Darren Schofield, Gianluca Carlesso, Kristen Pollizzi, Yariv Mazor, Michael Oberst, Scott A. Hammond, Brian Lobo, Prakash Manikwar, Jonathan Seaman, Simon Dovedi, Ronald Herbst