Abstract: Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.

Abstract: A system and method for providing automated UVC cleaning of shopping carts is disclosed. The system includes a first enclosing tunnel for containing one or more shopping carts during cleaning, one or more automatically opening and closing doors for enclosing any access to the first enclosing tunnel, a door lock coupled to each of the automatically opening and closing doors, a conveyor subsystem for loading and unloading shopping carts for cleaning within the first enclosing tunnel, and one or more UVC light source emitters contained within the first enclosing tunnel.

Abstract: Methods for quantifying the efficiency of nucleic acid extraction from a sample comprising a mixture of species are provided. In some embodiments, the method comprises adding an initial amount of one or more spike-ins to the sample, extracting nucleic acids from the sample, quantifying the amount of the one or more spike-ins in the extracted nucleic acid sample, and comparing the initial amount of the one or more spike-ins to the quantified amount of the one or more spike-ins.

Abstract: Methods for quantifying the efficiency of nucleic acid extraction from a sample comprising a mixture of species are provided. In some embodiments, the method comprises adding an initial amount of one or more spike-ins to the sample, extracting nucleic acids from the sample, quantifying the amount of the one or more spike-ins in the extracted nucleic acid sample, and comparing the initial amount of the one or more spike-ins to the quantified amount of the one or more spike-ins.

Abstract: Methods and systems for co-extruding multiple polymeric material flow streams into a mold having a plurality of cavities to produce a plurality of multi-layer polymeric articles each having a consistent coverage of an interior core layer are disclosed herein. In an example method, a flow rate of a first skin material into a cavity is individually controlled for each cavity before initiation of co-injection of a second core material into the cavity, which may address inconsistent interior core layer coverage for articles from different cavities.

Abstract: Methods and systems for co-extruding multiple polymeric material flow streams into a mold having a plurality of cavities to produce a plurality of multi-layer polymeric articles each having a consistent coverage of an interior core layer are disclosed herein. In an example method, a flow rate of a first skin material into a cavity is individually controlled for each cavity before initiation of co-injection of a second core material into the cavity, which may address inconsistent interior core layer coverage for articles from different cavities.

Abstract: Methods and systems for co-extruding multiple polymeric material flow streams into a mold having a plurality of cavities to produce a plurality of multi-layer polymeric articles each having a consistent coverage of an interior core layer are disclosed herein. In an example method, a flow rate of a first skin material into a cavity is individually controlled for each cavity before initiation of co-injection of a second core material into the cavity, which may address inconsistent interior core layer coverage for articles from different cavities.

Abstract: Methods and systems for co-extruding multiple polymeric material flow streams into a mold having a plurality of cavities to produce a plurality of multi-layer polymeric articles each having a consistent coverage of an interior core layer are disclosed herein. In an example method, a flow rate of a first skin material into a cavity is individually controlled for each cavity before initiation of co-injection of a second core material into the cavity, which may address inconsistent interior core layer coverage for articles from different cavities.

Abstract: Methods and systems for co-extruding multiple polymeric material flow streams into a mold having a plurality of cavities to produce a plurality of multi-layer polymeric articles each having a consistent coverage of an interior core layer are disclosed herein. In an example method, a flow rate of a first skin material into a cavity is individually controlled for each cavity before initiation of co-injection of a second core material into the cavity, which may address inconsistent interior core layer coverage for articles from different cavities.

Abstract: A system and containers for water filtration and item sanitization are described herein. In one embodiment, a water filtration device uses an extruded carbon sheet or granulated activated carbon to filter unpurified, gravity-fed water. The device can be a stand-alone water container or incorporated within a water purification system having a further purification technology located in a base in fluid communication with the water container. Other sanitizing containers can be used with the base to sanitize items while the water in the container is being sanitized. The base can include controls for informing a user when the water filtration or item sanitization has been completed. A method of sanitizing items is also disclosed. Practical applications include drinking water filtration, sanitization of household items, medical equipment, and the like.

Abstract: A multi-use sanitization system is disclosed which includes one or more containers in fluid communication with other system components. Components of the system include an ozone contacting device, such as a vortex-venturi or a sparger, for incorporating ozone into a liquid, an ozone generator to provide ozone to the vortex-venturi, a fluid transfer valve to allow simultaneous flow of liquid into and out of the container, and a pump to promote fluid flow through the system. Optionally, a gas-liquid separator with an optional integral gas release valve, an ozone destructor, an oxidation-reduction potential ozone sensor, or a pour-through type pre-filter may be incorporated into the system.