Abstract: Described herein are compositions and method for autologous adipose tissue grafting. In one embodiment, the composition comprises a recombinant partially ordered polypeptide (Fractomer) or “Fractomer” and adipose tissue from a subject. In one aspect, the Fractomer has the general structure of [(GXGVP)n-?-helix]m, where X can be any amino acid except proline and ?-helix is any polyalanine based ?-helix having about 5 to 50 Alanine residues. In another aspect, the Fractomer has the structure [(GXGVP)n-GX1(A)25X1]m; where X is A or V; X1 is K or D; n is an integer from 10 to 20; and m is an integer from 4 to 8.

Abstract: Systems and methods for updating a Domain Name System (DNS) registry are disclosed. Embodiments perform operations including maintaining a domain name record of a DNS registrant recorded in a database of the DNS registry by a primary DNS interface. The operations also include receiving a request to update the domain name record of the DNS registrant via a secondary DNS interface. The operations further include modifying the domain name record of the DNS registrant in the DNS database in accordance with the request.

Abstract: Systems and methods for updating a Domain Name System (DNS) registry are disclosed. Embodiments perform operations including maintaining a domain name record of a DNS registrant recorded in a database of the DNS registry by a primary DNS interface. The operations also include receiving a request to update the domain name record of the DNS registrant via a secondary DNS interface. The operations further include modifying the domain name record of the DNS registrant in the DNS database in accordance with the request.

Abstract: Systems and methods for updating a Domain Name System (DNS) registry are disclosed. Embodiments perform operations including maintaining a domain name record of a DNS registrant recorded in a database of the DNS registry by a primary DNS interface. The operations also include receiving a request to update the domain name record of the DNS registrant via a secondary DNS interface. The operations further include modifying the domain name record of the DNS registrant in the DNS database in accordance with the request.

Abstract: Embodiments relate to systems, devices, and computer-implemented methods for providing secure access to a shared registration system of a domain name registry by generating authorization information associated with a domain name, storing the authorization information in an archive, receiving, from a non-registrar service provider, a request for access to functionality of a shared registration system of the domain name registry, where the request is associated with the domain name and includes authorization information, determining whether the received authorization information is valid using the archived authorization information, and allowing the non-registrar service provider access to the functionality of the SRS based on a determination that the second authorization information is valid.

Abstract: Embodiments relate to systems, devices, and computer-implemented methods for providing secure access to a shared registration system of a domain name registry by generating authorization information associated with a domain name, storing the authorization information in an archive, receiving, from a non-registrar service provider, a request for access to functionality of a shared registration system of the domain name registry, where the request is associated with the domain name and includes authorization information, determining whether the received authorization information is valid using the archived authorization information, and allowing the non-registrar service provider access to the functionality of the SRS based on a determination that the second authorization information is valid.

Abstract: The present invention relates to methods of reducing ischemic damage to a surgical incision in a tissue of subject, enhancing tissue viability and vascularity following an ischemic event, and preconditioning tissue to resist an ischemic insult, which comprises contacting the relevant tissue topically with an effective dose of a HIF-1 potentiating agent, thereby reducing ischemic damage to a surgical incision, enhancing tissue viability and vascularity following an ischemic event, and preconditioning tissue to resist an ischemic insult.

Abstract: Systems and methods for updating a Domain Name System (DNS) registry are disclosed. Embodiments perform operations including maintaining a domain name record of a DNS registrant recorded in a database of the DNS registry by a primary DNS interface. The operations also include receiving a request to update the domain name record of the DNS registrant via a secondary DNS interface. The operations further include modifying the domain name record of the DNS registrant in the DNS database in accordance with the request.

Abstract: Provided is a method for providing a response to a user query for domain-related information of a domain. The method can include obtaining, at a client over a network, the user query for the domain-related information, and identifying one or more thick services based on thin data for the domain. The method can also include providing, by the client, the user query to the identified one or more thick services and obtaining a first answer to the user query from the one or more thick services. Furthermore, the method can include providing a second answer to a user based on the first answer.

Abstract: Systems and methods for updating a Domain Name System (DNS) registry are disclosed. Embodiments perform operations including maintaining a domain name record of a DNS registrant recorded in a database of the DNS registry by a primary DNS interface. The operations also include receiving a request to update the domain name record of the DNS registrant via a secondary DNS interface. The operations further include modifying the domain name record of the DNS registrant in the DNS database in accordance with the request.

Abstract: Provided is a method for providing a response to a user query for domain-related information of a domain. The method can include obtaining, at a client over a network, the user query for the domain-related information, and identifying one or more thick services based on thin data for the domain. The method can also include providing, by the client, the user query to the identified one or more thick services and obtaining a first answer to the user query from the one or more thick services. Furthermore, the method can include providing a second answer to a user based on the first answer.

Abstract: Provided is a method for providing Registration Data Access Protocol (“RDAP”) responses. The method includes obtaining, at a RDAP client over a network, a RDAP query for RDAP data from a user; providing, by the RDAP client, the RDAP query and a cryptographic credential to a RDAP server, wherein the RDAP server communicates with one or more thick RDAP servers to provide respective thick RDAP answers to the RDAP query, wherein at least one the respective thick RDAP answers are encrypted using a symmetric or asymmetric cryptographic key associated with the cryptographic credential of the RDAP client; obtaining a consolidated thick RDAP answer to the RDAP query from the RDAP server; decrypting the consolidated thick RDAP answer using a symmetric or asymmetric cryptographic key associated with the cryptographic credential; and providing the thick RDAP answer that is decrypted to the user.

Abstract: Provided is a method for providing Registration Data Access Protocol (“RDAP”) responses. The method includes obtaining, at a RDAP client over a network, a RDAP query for RDAP data from a user; providing, by the RDAP client, the RDAP query and a cryptographic credential to a RDAP server, wherein the RDAP server communicates with one or more thick RDAP servers to provide respective thick RDAP answers to the RDAP query, wherein at least one the respective thick RDAP answers are encrypted using a symmetric or asymmetric cryptographic key associated with the cryptographic credential of the RDAP client; obtaining a consolidated thick RDAP answer to the RDAP query from the RDAP server; decrypting the consolidated thick RDAP answer using a symmetric or asymmetric cryptographic key associated with the cryptographic credential; and providing the thick RDAP answer that is decrypted to the user.

Abstract: Embodiments relate to systems, devices, and computer-implemented methods for providing secure access to a shared registration system of a domain name registry by generating authorization information associated with a domain name, storing the authorization information in an archive, receiving, from a non-registrar service provider, a request for access to functionality of a shared registration system of the domain name registry, where the request is associated with the domain name and includes authorization information, determining whether the received authorization information is valid using the archived authorization information, and allowing the non-registrar service provider access to the functionality of the SRS based on a determination that the second authorization information is valid.

Abstract: Embodiments relate to systems, devices, and computer-implemented methods for providing secure access to a shared registration system of a domain name registry by generating authorization information associated with a domain name, storing the authorization information in an archive, receiving, from a non-registrar service provider, a request for access to functionality of a shared registration system of the domain name registry, where the request is associated with the domain name and includes authorization information, determining whether the received authorization information is valid using the archived authorization information, and allowing the non-registrar service provider access to the functionality of the SRS based on a determination that the second authorization information is valid.

Abstract: Provided is a method for providing Registration Data Access Protocol (“RDAP”) responses. The method includes obtaining, at a RDAP client over a network, a RDAP query for RDAP data from a user; providing, by the RDAP client, the RDAP query to one or more thick RDAP services; obtaining an answer to the RDAP query from the one or more thick RDAP services; and providing the answer to the user.

Abstract: Methods, systems, and computer program products are provided for optimizing searches of records including text elements. The methods, systems, and computer program perform operations including receiving a regular expression search query from a client. The operations also include parsing elements of the regular expression search query. The operations further include identifying search mechanisms based on the elements parsed from the search query. In addition, the operations include searching a data set identified by the regular expression search query using the search mechanisms. Further, the operations include returning a search result from the data set to the client based on a result of the searching.

Abstract: Provided is a method for providing Registration Data Access Protocol (“RDAP”) responses. The method includes obtaining, at a RDAP client over a network, a RDAP query for RDAP data from a user; providing, by the RDAP client, the RDAP query and a cryptographic credential to a RDAP server, wherein the RDAP server communicates with one or more thick RDAP servers to provide respective thick RDAP answers to the RDAP query, wherein at least one the respective thick RDAP answers are encrypted using a symmetric or asymmetric cryptographic key associated with the cryptographic credential of the RDAP client; obtaining a consolidated thick RDAP answer to the RDAP query from the RDAP server; decrypting the consolidated thick RDAP answer using a symmetric or asymmetric cryptographic key associated with the cryptographic credential; and providing the thick RDAP answer that is decrypted to the user.

Abstract: Provided is a method for providing Registration Data Access Protocol (“RDAP”) responses. The method includes obtaining, at a RDAP client over a network, a RDAP query for RDAP data from a user; providing, by the RDAP client, the RDAP query to one or more thick RDAP services; obtaining an answer to the RDAP query from the one or more thick RDAP services; and providing the answer to the user.

Abstract: Methods and systems are disclosed for quickly providing Whois services to a new top level domain after it is provisioned in a registry. In one embodiment, domain data is received at a first system regarding a top level domain (TLD). The domain data is assigned an authoritative port of a Whois server and is provisioned in a registry database. In certain embodiments, the Whois server provides information relating to domain name registrations of the TLD in the database, according to the authoritative port. The Whois server determines that a Whois query is received at the authoritative port for the queried TLD and responds with the queried information. To the requester, the responses appear as if they are sent from a unique Whois server for each TLD, but the Whois server is actually shared among the TLDs.