Patents by Inventor Scott J. Dixon

Scott J. Dixon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds, compositions, and methods for modulating ferroptosis and treating excitotoxic disorders
    Patent number: 10597381
    Abstract: The present invention provides, inter alia, a compound having the structure: Also provided are compositions containing a pharmaceutically acceptable carrier and a compound according to the present invention. Further provided are methods for treating or ameliorating the effects of an excitotoxic disorder in a subject, methods of modulating ferroptosis in a subject, methods of reducing reactive oxygen species (ROS) in a cell, and methods for treating or ameliorating the effects of a neurodegenerative disease.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: March 24, 2020
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Brent R. Stockwell, Scott J. Dixon, Rachid Skouta
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS
    Publication number: 20190135782
    Abstract: The present invention provides, inter alia, a compound having the structure: Also provided are compositions containing a pharmaceutically acceptable carrier and a compound according to the present invention. Further provided are methods for treating or ameliorating the effects of an excitotoxic disorder in a subject, methods of modulating ferroptosis in a subject, methods of reducing reactive oxygen species (ROS) in a cell, and methods for treating or ameliorating the effects of a neurodegenerative disease.
    Type: Application
    Filed: January 14, 2019
    Publication date: May 9, 2019
    Inventors: Brent R. Stockwell, Scott J. Dixon, Rachid Skouta
  • Compounds, compositions, and methods for modulating ferroptosis and treating excitotoxic disorders
    Patent number: 10233171
    Abstract: The present invention provides, inter alia, a compound having the structure: Also provided are compositions containing a pharmaceutically acceptable carrier and a compound according to the present invention. Further provided are methods for treating or ameliorating the effects of an excitotoxic disorder in a subject, methods of modulating ferroptosis in a subject, methods of reducing reactive oxygen species (ROS) in a cell, and methods for treating or ameliorating the effects of a neurodegenerative disease.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: March 19, 2019
    Inventors: Brent R. Stockwell, Scott J. Dixon, Rachid Skouta
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS
    Publication number: 20170233370
    Abstract: The present invention provides, inter alia, a compound having the structure: Also provided are compositions containing a pharmaceutically acceptable carrier and a compound according to the present invention. Further provided are methods for treating or ameliorating the effects of an excitotoxic disorder in a subject, methods of modulating ferroptosis in a subject, methods of reducing reactive oxygen species (ROS) in a cell, and methods for treating or ameliorating the effects of a neurodegenerative disease.
    Type: Application
    Filed: February 24, 2017
    Publication date: August 17, 2017
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Brent R. Stockwell, Scott J. Dixon, Rachid Skouta
  • Compounds, compositions, and methods for modulating ferroptosis and treating excitotoxic disorders
    Patent number: 9580398
    Abstract: The present invention provides, inter alia, a compound having the structure: (Formula (I). Also provided are compositions containing a pharmaceutically acceptable carrier and a compound according to the present invention. Further provided are methods for treating or ameliorating the effects of an excitotoxic disorder in a subject, methods of modulating ferroptosis in a subject, methods of reducing reactive oxygen species (ROS) in a cell, and methods for treating or ameliorating the effects of a neurodegenerative disease.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: February 28, 2017
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Brent R. Stockwell, Scott J. Dixon, Rachid Skouta
  • Compounds, Compositions, and Methods For Modulating Ferroptosis and Treating Excitotoxic Disorders
    Publication number: 20150079035
    Abstract: The present invention provides, inter alia, a compound having the structure: (Formula (I). Also provided are compositions containing a pharmaceutically acceptable carrier and a compound according to the present invention. Further provided are methods for treating or ameliorating the effects of an excitotoxic disorder in a subject, methods of modulating ferroptosis in a subject, methods of reducing reactive oxygen species (ROS) in a cell, and methods for treating or ameliorating the effects of a neurodegenerative disease.
    Type: Application
    Filed: April 2, 2013
    Publication date: March 19, 2015
    Inventors: Brent R. Stockwell, Scott J. Dixon, Rachid Skouta
  • Solid propellant with titanate bonding agent
    Patent number: 5753853
    Abstract: Liquid elastomer-based propellant having incorporated therein organo-titanate compounds are described. The organo-titanates have positive ballistic and physical effects on the propellants, serving to reduce burn rate exponents and overall burn rates, as well as increasing the tensile strength and elasticity of the propellant. Organo-phosphate and pyrophosphate titanates are used as the preferred organo-titanates.
    Type: Grant
    Filed: February 20, 1986
    Date of Patent: May 19, 1998
    Assignee: Kenrich Petrochemicals, Inc.
    Inventors: Salvatore J. Monte, Gerald Sugerman, Scott J. Dixon