Abstract: An antimicrobial device, such as a flashlight, lantern, or lamp, is discussed herein. The antimicrobial device produces light in the ultraviolet (UV) spectrum (i.e., 150-250 nm), including 200-230 nm. The antimicrobial device includes an electron source, an extractor, and a target material. The electron source provides the electrons of sufficient energy to cause a photon to be released, whether by a target or by the electron itself. The extractor extracts the electrons from the electron source. The target material is a component at which the electron is directed. The target material can release a photon having a desired wavelength or within a desired wavelength range or cause the electron to release a photon having a desired wavelength or within a desired wavelength range.

Abstract: Techniques for a modeling platform associated with simulating risk models. According to certain aspects, systems and methods include simulating the impact of qualitative assumptions on the risk model. Accordingly, the risk model may include a hierarchical tree formed of component qualitative assumption objects and quantitative assumption objects. Quantitative assumption objects include indications of distribution function parameters associated with the assumption object and qualitative assumption objects include an indication of an impact on a parent quantitative assumption. When simulating the risk model, systems and methods may adjust sampled values quantitative assumption object when a child qualitative assumption object is enabled.

Abstract: Techniques for a modeling platform associated with simulating risk models. According to certain aspects, systems and methods include simulating the risk model over time. The risk model may include a hierarchical tree formed of component assumption objects associated with distribution functions. The systems and methods may apply a time function to generate time-adjusted values for the component assumption objects corresponding to defined distribution functions. The systems and methods may then combine the time-adjusted values to generate time-adjusted values for parent assumption objects.

Abstract: A system for generating a custom audio experience that is configured receive a first audio sample of a first impulse response corresponding to an interior of a vehicle, generate a first convolution reverb from the first audio sample, receive a second audio sample of a second impulse response corresponding to an audio equipment of the vehicle, generate an impulse response module from the second audio sample, generate combination module based on the first convolution reverb and the impulse response module, receive a third audio sample from a user, modify the third audio sample based on the combination module to generate a modified third audio sample, receive an indication of user input to play the modified third audio sample, and cause a user device to output the modified third audio sample.

Abstract: A computing component is described. The computing component includes a cosmetic prefabricated sheet of material. In some embodiments, the cosmetic prefabricated sheet of material may have a cosmetic surface and a protrusion surface. The computing component includes a protrusion extending from the protrusion surface of the cosmetic prefabricated sheet of material. In some embodiments, the cosmetic surface of the cosmetic prefabricated sheet of material is uniform in appearance to the naked eye. In some embodiments, the protrusion may have a base and an end. The base may have a cross-sectional width and the end may have a cross-sectional width. A difference in the cross-sectional width of the base and the cross-sectional width of the end may be less than 250 microns.

Abstract: Antibody conjugates with camptothecin compounds are described, with methods of use and preparations.

Abstract: Methods and systems for adjusting device functions based on ambient conditions or battery status are disclosed. When environmental or device conditions reach a threshold level, device function such as display brightness or display refresh rate may be adjusted. One such example, may include a method and system for image fusion with a wide camera and a second image from a narrow camera to create a composite image with unnoticeable blending between the images.

Abstract: A method of transferring at least one subterranean core sample from a retrieval vessel to a testing vessel can include removing at least one pressure barrier on the retrieval vessel using a linear actuator while maintaining a sampling pressure on the at least one subterranean core sample at which the at least one subterranean core sample is taken from a subterranean formation. The method can also include pressurizing the testing vessel to the sampling pressure using the linear actuator, and transferring the at least one subterranean core sample from the retrieval vessel to the testing vessel. The method can further include sealing the testing vessel with the at least one subterranean core sample at the sampling pressure, where the testing vessel allows the at least one subterranean core sample to be tested while the at least one subterranean core sample is maintained at the sampling pressure.

Abstract: Examples are disclosed that relate to a compact optical systems comprising SLMs. One example provides a projection system comprising an illumination stage including a light emitting diode (LED) array. The LED array comprises a plurality of red LEDs, a plurality of green LEDs, and a plurality of blue LEDs. The illumination stage further comprises an illumination stage optical system configured to control an angular extent of light emitted by the LED array and homogenize the light emitted by the LED array. The projection system further comprises an image forming stage configured to form an image from light output by the illumination stage, the image forming stage comprising a spatial light modulator (SLM) configured to spatially modulate the light output by the illumination stage to form an image, and one or more projection optics configured to project the image formed by the spatial light modulator.

Abstract: A charging system for a peripheral device, such as a stylus, including orientation control. The charging system includes charging circuitry and magnets. The magnets are configured so that they attract the peripheral device to an engagement surface when it is in a first orientation relative to the engagement surface so that charging circuitry in a peripheral device portion couples with charging circuitry in a charger portion. The magnets are configured so that they also repel and rotate the peripheral device when it is in a second orientation relative to the engagement surface.

Abstract: A headset for use with immersive reality applications is provided. The headset includes a left eyepiece and a right eyepiece mounted on a frame, a display in at least one of the left eyepiece or the right eyepiece, the display comprising an array of multiple light emitting pixels, an ambient light sensor to measure an amount of ambient light, and a processor configured to control a light intensity of the light emitting pixels based on the amount of ambient light. A method for using the above headset is also provided.

Abstract: Techniques for a modeling platform associated with simulating risk models. According to certain aspects, systems and methods include simulating the impact of qualitative assumptions on the risk model. Accordingly, the risk model may include a hierarchical tree formed of component qualitative assumption objects and quantitative assumption objects. Quantitative assumption objects include indications of distribution function parameters associated with the assumption object and qualitative assumption objects include an indication of an impact on a parent quantitative assumption. When simulating the risk model, systems and methods may adjust sampled values quantitative assumption object when a child qualitative assumption object is enabled.

Abstract: Techniques for a modeling platform associated with simulating risk models. According to certain aspects, systems and methods include simulating the risk model over time. The risk model may include a hierarchical tree formed of component assumption objects associated with distribution functions. The systems and methods may apply a time function to generate time-adjusted values for the component assumption objects corresponding to defined distribution functions. The systems and methods may then combine the time-adjusted values to generate time-adjusted values for parent assumption objects.

Abstract: Techniques for a modeling platform associated with simulating risk models. According to certain aspects, systems and methods include identifying sources of uncertainty within the risk model. The risk model may include a hierarchical tree formed of component assumption objects associated with distribution functions. The systems and methods may include calculating an uncertainty contribution for assumption objects included in the risk model by setting the value for a particular assumption object to a constant value and executing an additional simulation of the risk model. The amount by which the uncertainty corresponding to the risk model changes between simulations may correspond to the uncertainty contribution for the particular assumption object.

Abstract: The invention relates to conjugates of biologically active compounds, wherein such a conjugate is comprised of a sequence of amino acids containing a tripeptide that confers selective cleavage by tumor tissue homogenate for release of free drug and/or improves biodistribution into the tumor tissue in comparison to normal tissue homogenate from the same species, wherein the normal tissue is the site of an adverse event associated with administration to a human subject in need thereof of a therapeutically effective amount of a comparator conjugate whose amino acid sequence is a dipeptide known to be selectively cleavable by Cathepsin B.

Abstract: Antibody conjugates with camptothecin compounds are described, with methods of use and preparations.

Abstract: A system for conducting a beverage tasting event includes a plurality of beverage containers, a plurality of distinct identifiers, a plurality of distinct covers, and a set of instruction materials. The set of instruction materials instructs a first participant to privately assign a correspondence between each distinct beverage and a distinct identifier, and to privately transfer distinct beverages into beverage containers with the distinct identifiers visibly displayed in accordance with each assigned correspondence.

Abstract: A method of executing a double blind wine tasting event comprises providing a plurality of distinct wine bottles, a plurality of identical sleeves and a plurality of distinct covers. A first person places each of the wine bottles in a respective sleeve, with each of the sleeves including a respective distinct identifier. The first person keeps track of which wine bottle is placed in which sleeve. A second person then masks each of the identifiers with a respective cover, with each of the covers being removably attachable to the sleeves. The second person keeps track of which cover is masking which identifier. After these steps are carried out, a location of each of the wine bottles within the sleeves is unknown to every one of the participants. A plurality of carafes may be used as an alternative to the sleeves.

Abstract: Provided herein are Camptothecin Conjugates, Camptothecin-Linker Compounds, Camptothecin Compounds, intermediates thereof, and method of preparing the same. Also provided herein are methods of treating cancer and autoimmune diseases with the Conjugates described herein.

Abstract: A device including a plurality of motors is disclosed. The device includes a body comprising a plurality of magnet arrays. Each magnet array comprises a plurality of magnets which define a polygon and the plurality of magnets are arranged in a semi-Halbach configuration. The polygons of the plurality of magnet arrays form a tessellating pattern in which the magnet arrays each share at least one magnet with another one of the magnet arrays. Each magnet is configured to be rotatable relative to the body, or in the case of coils as magnets, the input of each coil can be manipulated to replicate the same or similar effect. The device further comprises a plurality of rotors, wherein each magnet array is configured to receive a rotor rotatable relative to the body.