Patents by Inventor Scott Kendall Dessain

Scott Kendall Dessain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS COMPRISING FUSION PROTEINS FOR THE IDENTIFICATION OF IMMUNOTHERAPY CELLS
    Publication number: 20240060043
    Abstract: Fusion proteins, comprising at least one single chain antibody fragment (scFV), and a cancer antigen or marker, or a fragment thereof are provided. The scFV is capable of selectively binding to a cytokine released by chimeric antigen receptor (CAR) expressing cell such as interferon gamma (IFN-?) or tumor necrosis factor alpha (TNF-?). The cancer antigen or marker may comprise the extracellular domain of CD19. Methods for isolating or purifying CAR expressing cells using fusion proteins are provided.
    Type: Application
    Filed: July 24, 2023
    Publication date: February 22, 2024
    Applicants: Villanova University, Lankenau Institute for Medical Research
    Inventors: William Joseph Kelly, III, Justin Thomas Fisher, Scott Kendall Dessain
  • PDK1 BINDING MOLECULES AND USES THEREOF
    Publication number: 20160319035
    Abstract: The present invention is based, at least in part, on the discovery that PDK1 is associated with the outer plasma membrane of the cell. Accordingly, the present invention encompasses 3-phosphoinositide-dependent protein kinase-1 (PDK1) binding molecules, such as an antibody. The binding molecules of the invention are useful for detecting PDK1 and for inhibiting PDK1 activity, e.g., in a human subject having a disorder in which PDK1 activity is detrimental, such as a cancer.
    Type: Application
    Filed: December 7, 2015
    Publication date: November 3, 2016
    Inventors: Scott Kendall Dessain, Baron Christopher Heimbach