Patents by Inventor Scott Kuduk

Scott Kuduk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted aminopyridine compounds as EGFR inhibitors
    Patent number: 11945798
    Abstract: Provided are aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.
    Type: Grant
    Filed: August 26, 2022
    Date of Patent: April 2, 2024
    Assignees: YUHAN CORPORATION, JANSSEN BIOTECH, INC.
    Inventors: Hyunjoo Lee, Su Bin Choi, Young Ae Yoon, Kwan Hoon Hyun, Jae Young Sim, Marian C. Bryan, Scott Kuduk, James Campbell Robertson, Jaekyoo Lee, Paresh Devidas Salgaonkar, Byung-Chul Suh, Jong Sung Koh, So Young Hwang
  • Dihydroorotate dehydrogenase inhibitors
    Patent number: 11753393
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, X, and Y are defined herein.
    Type: Grant
    Filed: May 12, 2022
    Date of Patent: September 12, 2023
    Inventors: Scott Kuduk, Zhuming Zhang, Lindsey DeRatt, Aihua Wang
  • SUBSTITUTED AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS
    Publication number: 20230086795
    Abstract: Provided are aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.
    Type: Application
    Filed: August 26, 2022
    Publication date: March 23, 2023
    Applicants: YUHAN CORPORATION, JANSSEN BIOTECH, INC.
    Inventors: Hyunjoo LEE, Su Bin CHOI, Young Ae YOON, Kwan Hoon HYUN, Jae Young SIM, Marian C. BRYAN, Scott KUDUK, James Campbell Robertson, Jaekyoo LEE, Paresh Devidas SALGAONKAR, Byung-Chul SUH, Jong Sung KOH, So Young HWANG
  • SUBSTITUTED AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS
    Publication number: 20230086884
    Abstract: Provided are aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.
    Type: Application
    Filed: August 26, 2022
    Publication date: March 23, 2023
    Applicants: YUHAN CORPORATION, JANSSEN BIOTECH, INC.
    Inventors: Byoungmoon LEE, Hyunjoo LEE, Gyu Jin LEE, Su Bin CHOI, Sol PARK, Heejun KIM, Misong KIM, Young Ae YOON, Kwan Hoon HYUN, Tae Kyun KIM, Jae Young SIM, Marian C. BRYAN, Scott KUDUK, James Campbell ROBERTSON
  • 5-MEMBERED HETEROARYL-CONTAINING AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS
    Publication number: 20230085912
    Abstract: Provided are 5-membered heteroaryl-containing aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.
    Type: Application
    Filed: August 26, 2022
    Publication date: March 23, 2023
    Applicants: YUHAN CORPORATION, JANSSEN BIOTECH, INC.
    Inventors: Byoungmoon LEE, Hyunjoo LEE, Gyu Jin LEE, Su Bin CHOI, Misong KIM, Young Ae YOON, Kwan Hoon HYUN, Jae Young SIM, Marian C. BRYAN, Scott KUDUK, James Campbell ROBERTSON, Jaekyoo LEE, Paresh Devidas SALGAONKAR, Byung-Chul SUH, Jong Sung KOH, So Young HWANG
  • FLUORINATED QUINOLINE AND QUINOXALINE DERIVATIVES AS DIHYDROOROTATE DEHYDROGENASE (DHODH) INHIBITORS FOR THE TREATMENT OF CANCER, AUTOIMMUNE AND INFLAMMATORY DISEASES
    Publication number: 20230037448
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula (I) as follows: wherein R1a, R1b, R2, and R3, are defined herein.
    Type: Application
    Filed: October 30, 2020
    Publication date: February 9, 2023
    Inventors: Justin Cisar, Colleen Keohane, Scott Kuduk
  • Dihydroorotate dehydrogenase inhibitors
    Patent number: 11505536
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, X, and Y are defined herein.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: November 22, 2022
    Inventors: Scott Kuduk, Zhuming Zhang, Lindsey DeRatt, Aihua Wang
  • SUBSTITUTED UREA DIHYDROOROTATE DEHYDROGENASE INHIBITORS
    Publication number: 20220298107
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula I as follows: wherein R1, R2, R3 and R6 are defined herein.
    Type: Application
    Filed: August 27, 2020
    Publication date: September 22, 2022
    Inventors: Scott Kuduk, Lindsey DeRatt
  • DIHYDROOROTATE DEHYDROGENASE INHIBITORS
    Publication number: 20220298137
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, X, and Y are defined herein.
    Type: Application
    Filed: May 12, 2022
    Publication date: September 22, 2022
    Inventors: Scott Kuduk, Zhuming Zhang, Lindsey DeRatt, Aihua Wang
  • ISOXAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH HBV INFECTIONS
    Publication number: 20220135590
    Abstract: Provided herein are isoxazole compounds, pharmaceutical compositions thereof, methods of preparing such compounds and compositions, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
    Type: Application
    Filed: December 21, 2018
    Publication date: May 5, 2022
    Inventors: Scott KUDUK, Sandrine Marie Helene VENDEVILLE
  • DIHYDROOROTATE DEHYDROGENASE INHIBITORS
    Publication number: 20220089568
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula (I) as follows: wherein R1a, R1b, R2, and R3, are defined herein.
    Type: Application
    Filed: January 10, 2020
    Publication date: March 24, 2022
    Inventors: Justin Cisar, Scott Kuduk, Chao-yuan Wang, Yvan Rene Ferdinand Simonnet, Colleen Elizabeth Keohane, Edgar Jacoby
  • DIHYDROOROTATE DEHYDROGENASE INHIBITORS
    Publication number: 20220081422
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Embodiments of such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5a, R5b, X and Y, are defined herein.
    Type: Application
    Filed: February 6, 2020
    Publication date: March 17, 2022
    Inventors: Justin Cisar, Scott Kuduk, Zhuming Zhang, Aihua Wang, Yvan Simonnet
  • OXADIAZEPINONE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS
    Publication number: 20210252014
    Abstract: Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
    Type: Application
    Filed: February 22, 2021
    Publication date: August 19, 2021
    Inventors: Scott Kuduk, George D. Hartman
  • DIAZEPINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEPATITIS B INFECTIONS
    Publication number: 20210188849
    Abstract: Provided herein are compounds of formula (I) and (V) useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
    Type: Application
    Filed: February 22, 2021
    Publication date: June 24, 2021
    Inventors: Scott Kuduk, George D. Hartman
  • Oxadiazepinone derivatives and methods of treating hepatitis B infections
    Patent number: 10987359
    Abstract: Provided herein are compounds of formula (IA) and (III) useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: April 27, 2021
    Assignee: Novira Therapeutics, Inc.
    Inventors: Scott Kuduk, George D. Hartman
  • Diazepinone derivatives and their use in the treatment of hepatitis B infections
    Patent number: 10975077
    Abstract: Provided herein are compounds of formula (I) and (V) useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: April 13, 2021
    Assignee: Novira Therapeutics, Inc.
    Inventors: Scott Kuduk, George D. Hartman
  • DIHYDROOROTATE DEHYDROGENASE INHIBITORS
    Publication number: 20200331881
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, X, and Y are defined herein.
    Type: Application
    Filed: April 16, 2020
    Publication date: October 22, 2020
    Inventors: Scott Kuduk, Zhuming Zhang, Lindsey DeRatt, Aihua Wang
  • OXADIAZEPINONE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS
    Publication number: 20200197408
    Abstract: Provided herein are compounds of formula (IA) and (III) useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
    Type: Application
    Filed: June 29, 2017
    Publication date: June 25, 2020
    Inventors: Scott Kuduk, George D. Hartman
  • Derivatives And Methods Of Treating Hepatitis B Infections
    Publication number: 20200181142
    Abstract: Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
    Type: Application
    Filed: December 3, 2019
    Publication date: June 11, 2020
    Inventors: George D. Hartman, Scott Kuduk
  • DIAZEPINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEPATITIS B INFECTIONS
    Publication number: 20200181144
    Abstract: Provided herein are compounds of formula (I) and (V) useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
    Type: Application
    Filed: June 29, 2017
    Publication date: June 11, 2020
    Inventors: Scott Kuduk, George D. Hartman