Patents by Inventor Scott L. Childs
Scott L. Childs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250034115Abstract: Crystalline forms of a C-C chemokine receptor type 4 (CCR4) antagonist, oral dosage forms of same and methods of using and preparing same are provided.Type: ApplicationFiled: July 10, 2024Publication date: January 30, 2025Inventors: Scott L. Childs, James P. Davidson, David J. Wustrow, Ashkaan Younai
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Publication number: 20230339967Abstract: This application relates to solid forms of an S1P-receptor modulator, which are useful in the treatment of diseases or disorders associated with activity of S1P, including CNS disorders.Type: ApplicationFiled: November 22, 2022Publication date: October 26, 2023Inventors: Stéphane De Lombaert, Ana Rosario Mollo Sarno, Michael A. Christie, Edward L. Ciolkowski, Susana del Rio Gancedo, Joseph Stephen Harris, Lucy Kristina Mapp, Mateusz Bogumil Pitak, Scott L. Childs
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Patent number: 11535632Abstract: This application relates to solid forms of an S1P-receptor modulator, which are useful in the treatment of diseases or disorders associated with activity of S1P, including CNS disorders.Type: GrantFiled: October 30, 2020Date of Patent: December 27, 2022Assignee: ESCAPE Bio, Inc.Inventors: Stéphane De Lombaert, Ana Rosario Mool Sarno, Michael A. Christie, Edward L. Ciolkowski, Susana del Rio Gancedo, Joseph Stephen Harris, Lucy Kristina Mapp, Mateusz Bogumil Pitak, Scott L. Childs
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Publication number: 20210139502Abstract: This application relates to solid forms of an S1P-receptor modulator, which are useful in the treatment of diseases or disorders associated with activity of S1P, including CNS disorders.Type: ApplicationFiled: October 30, 2020Publication date: May 13, 2021Inventors: Stéphane De Lombaert, Ana Rosario Mollo Sarno, Michael A. Christie, Edward L. Ciolkowski, Susana del Rio Gancedo, Joseph Stephen Harris, Lucy Kristina Mapp, Mateusz Bogumil Pitak, Scott L. Childs
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Patent number: 10100032Abstract: The invention relates to novel crystalline forms of 3-(4-amino-l-oxo-l,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione, including a novel urea cocrystal of 3-(4-amino-l-oxo-l,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione; a novel gallic acid cocrystal of 3-(4-amino-l-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione; a novel propyl gallate cocrystal of 3-(4-amino-l-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione; and a novel L-tartaric acid cocrystal of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione. The preparation and characterization of the novel crystalline forms according to various embodiments of the invention are described. The invention also relates to pharmaceutical compositions containing the novel crystalline forms, and the therapeutic use of the novel crystalline forms.Type: GrantFiled: December 2, 2016Date of Patent: October 16, 2018Assignee: AMPLIO PHARMA, LLCInventors: Scott L. Childs, Shreenivas R. Lingireddy, Nathan Barishansky
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Patent number: 9540341Abstract: The invention relates to novel crystalline forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione, including a novel urea cocrystal of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione; a novel gallic acid cocrystal of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione; a novel propyl gallate cocrystal of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione; and a novel L-tartaric acid cocrystal of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione. The preparation and characterization of the novel crystalline forms according to various embodiments of the invention are described. The invention also relates to pharmaceutical compositions containing the novel crystalline forms, and the therapeutic use of the novel crystalline forms.Type: GrantFiled: June 7, 2012Date of Patent: January 10, 2017Assignee: AMPLIO PHARMA, LLCInventors: Scott L. Childs, Shreenivas R. Lingireddy, Nathan Barishansky
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Patent number: 9421182Abstract: Disclosed herein are cocrystals of dimethyl fumarate, which is a prodrug of methyl hydrogen fumarate.Type: GrantFiled: June 20, 2014Date of Patent: August 23, 2016Assignee: XenoPort, Inc.Inventors: Chen Mao, Scott L. Childs, Sami Karaborni
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Publication number: 20150157590Abstract: Disclosed herein are cocrystals of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate.Type: ApplicationFiled: November 5, 2013Publication date: June 11, 2015Applicant: XenoPort, Inc.Inventors: Chen Mao, Scott L. Childs
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Patent number: 8920559Abstract: The present disclosure relates to crystallizing a chemical substance(s) using ultrasound. Methods are provided for screening a chemical substance according to its solid forms by using ultrasound to generate new or unusual solid forms. Methods are also provided for crystallizing a chemical substance by novel techniques that include sonication. The present disclosure also relates to cocrystallization using ultrasound. Methods are provided for preparing cocrystals of an active agent and a guest by sonicating and crystallizing. Methods are also provided for screening a sample according to solid state phases (such as cocrystals and salts) and include generating a cocrystal from the sample using ultrasound.Type: GrantFiled: September 22, 2010Date of Patent: December 30, 2014Assignee: Aptuit (West Lafayette), LLCInventors: Scott L. Childs, Patricia M. Mougin-Andres, Barbara C. Stahly
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Publication number: 20140378542Abstract: Disclosed herein are cocrystals of dimethyl fumarate, which is a prodrug of methyl hydrogen fumarate.Type: ApplicationFiled: June 20, 2014Publication date: December 25, 2014Inventors: Chen Mao, Scott L. Childs, Sami Karaborni
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Publication number: 20140296291Abstract: The invention relates to novel crystalline forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione, including a novel urea cocrystal of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione; a novel gallic acid cocrystal of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione; a novel propyl gallate cocrystal of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione; and a novel L-tartaric acid cocrystal of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione. The preparation and characterization of the novel crystalline forms according to various embodiments of the invention are described. The invention also relates to pharmaceutical compositions containing the novel crystalline forms, and the therapeutic use of the novel crystalline forms.Type: ApplicationFiled: June 7, 2012Publication date: October 2, 2014Inventors: Scott L. Childs, Shreenivas R. Lingireddy, Nathan Barishansky
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Publication number: 20140179778Abstract: Disclosed herein are cocrystals of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate.Type: ApplicationFiled: November 5, 2013Publication date: June 26, 2014Applicant: XenoPort, Inc.Inventors: Chen Mao, Scott L. Childs
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Patent number: 8350085Abstract: The present disclosure relates to novel cocrystals and novel methods for cocrystallization. In particular, the disclosure includes cocrystals comprising a salt of an active agent, such as a chloride salt of an active pharmaceutical ingredient. The present disclosure also relates to methods of preparing cocrystals and methods for screening for solid state phases.Type: GrantFiled: June 28, 2011Date of Patent: January 8, 2013Assignee: New Form Pharmaceuticals Inc.Inventor: Scott L. Childs
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Patent number: 8212079Abstract: The present disclosure relates to novel cocrystals and novel methods for cocrystallization. In particular, the disclosure includes cocrystals comprising a salt of an active agent, such as a chloride salt of an active pharmaceutical ingredient. The present disclosure also relates to methods of preparing cocrystals and methods for screening for solid state phases.Type: GrantFiled: September 19, 2008Date of Patent: July 3, 2012Assignee: Aptuit (West Lafayette), LLCInventor: Scott L. Childs
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Publication number: 20110251426Abstract: The present disclosure relates to crystallizing a chemical substance(s) using ultrasound. Methods are provided for screening a chemical substance according to its solid forms by using ultrasound to generate new or unusual solid forms. Methods are also provided for crystallizing a chemical substance by novel techniques that include sonication. The present disclosure also relates to cocrystallization using ultrasound. Methods are provided for preparing cocrystals of an active agent and a guest by sonicating and crystallizing. Methods are also provided for screening a sample according to solid state phases (such as cocrystals and salts) and include generating a cocrystal from the sample using ultrasound.Type: ApplicationFiled: September 22, 2010Publication date: October 13, 2011Applicant: S.S.C.I., Inc.Inventors: Scott L. Childs, Patricia M. Mougin-Andres, Barbara C. Stahly
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Patent number: 7924033Abstract: A compensation tool and process is provided for calibrating each test position located at a plurality of test modules of an electronic testing machine to a standardized value. Each test module is located on an angularly spaced radial line extending from an associated central axis and has a plurality of contacts for testing electronic components. The compensation tool can include a body having an axis of rotation coaxially alignable with the central axis for rotation to different angular positions and a component-support member operably associated with the body for indexing movement to selectively align a pocket with different contacts associated with each test position located at each of the plurality of test modules. The pocket of the component-support member receives an electronic component with terminated ends extending outwardly to allow electrical contact and testing of each test position located at each the plurality of test modules.Type: GrantFiled: March 21, 2008Date of Patent: April 12, 2011Assignee: Electro Scientific Industries, Inc.Inventors: Scott L. Child, Nick A. Tubbs
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Publication number: 20090237096Abstract: A compensation tool and process is provided for calibrating each test position located at a plurality of test modules of an electronic testing machine to a standardized value. Each test module is located on an angularly spaced radial line extending from an associated central axis and has a plurality of contacts for testing electronic components. The compensation tool can include a body having an axis of rotation coaxially alignable with the central axis for rotation to different angular positions, and a component-support member operably associated with the body for indexing movement to selectively align with different contacts associated with each test position located at each of the plurality of test modules. The component-support member can include a pocket for receiving an electronic component with terminated ends extending outwardly to allow electrical contact and testing of each test position located at each the plurality of test modules.Type: ApplicationFiled: March 21, 2008Publication date: September 24, 2009Applicant: ELECTRO SCIENTIFIC INDUSTRIESInventors: Scott L. Child, Nick A. Tubbs
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Patent number: 7452555Abstract: The present disclosure relates to novel cocrystals and novel methods for cocrystallization. In particular, the disclosure includes cocrystals comprising a salt of an active agent, such as a chloride salt of an active pharmaceutical ingredient. The present disclosure also relates to methods of preparing cocrystals and methods for screening for solid state phases.Type: GrantFiled: January 21, 2004Date of Patent: November 18, 2008Assignee: S.S.C.I., Inc.Inventor: Scott L. Childs
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Publication number: 20040176335Abstract: The present disclosure relates to novel cocrystals and novel methods for cocrystallization. In particular, the disclosure includes cocrystals comprising a salt of an active agent, such as a chloride salt of an active pharmaceutical ingredient. The present disclosure also relates to methods of preparing cocrystals and methods for screening for solid state phases.Type: ApplicationFiled: January 21, 2004Publication date: September 9, 2004Inventor: Scott L. Childs