Patents by Inventor Scott L. Delp
Scott L. Delp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11596791Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: GrantFiled: February 1, 2021Date of Patent: March 7, 2023Assignee: Cala Health, Inc.Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Richard Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Publication number: 20210330974Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: ApplicationFiled: February 1, 2021Publication date: October 28, 2021Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Richard Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Publication number: 20210308460Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: ApplicationFiled: March 29, 2021Publication date: October 7, 2021Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Publication number: 20210290104Abstract: A training method is provided to train changing muscle contribution in a human subject while the human subject is performing a complex movement. Feedback is provided in a simple understandable fashion by one or more data points calculated based on electromyography signals obtained over e.g. a stance phase of a walking cycle. The training method showed a significantly increased training effect in subjects performing these complex movements where these subjects were able to change the muscle activation given a specific goal. The training could be setup of a single muscle or multiple muscles. The data point feedback could be a measure for the single muscle or some relative measure for the multiple muscles. The training method results in improved coordination strategies and could be useful for retraining purposes as well as intervention methods for musculoskeletal pathologies or movement disorders.Type: ApplicationFiled: July 3, 2019Publication date: September 23, 2021Inventors: Scott David Uhlrich, Scott L. Delp
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Patent number: 11103723Abstract: Provided herein are methods for the treatment of bladder dysfunction, including detrusor hyperreflexia and detrusor external sphincter dyssynergia, fecal incontinence, and/or sexual dysfunction in an individual via the use of stably expressed light-responsive opsin proteins capable of selective hyperpolarization or depolarization of the neural cells that innervate the muscles responsible for physiologic functioning of urinary bladder, external urinary sphincter, external anal sphincter, and the male and female genitalia.Type: GrantFiled: October 23, 2015Date of Patent: August 31, 2021Assignees: The Board of Trustees of the Leland Stanford Junior University, Circuit Therapeutics, Inc.Inventors: Karl A. Deisseroth, Elizabeth R. Aden, Viviana Gradinaru, Scott L. Delp
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Patent number: 10960207Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes, Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: GrantFiled: February 14, 2020Date of Patent: March 30, 2021Assignee: CALA HEALTH, INC.Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Patent number: 10905879Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: GrantFiled: February 3, 2020Date of Patent: February 2, 2021Assignee: Cala Health, Inc.Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Richard Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Publication number: 20200254251Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: ApplicationFiled: February 3, 2020Publication date: August 13, 2020Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Richard Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Publication number: 20200179687Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes, Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: ApplicationFiled: February 14, 2020Publication date: June 11, 2020Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Publication number: 20200121942Abstract: The present disclosure provides compositions and methods for controlling pain. The present disclosure provides methods for identifying agents that control pain.Type: ApplicationFiled: April 18, 2019Publication date: April 23, 2020Inventors: Shrivats Mohan Iyer, Scott L. Delp, Kathryn L. Montgomery, Karl A. Deisseroth, Christopher Towne
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Publication number: 20200100659Abstract: Biological tissue such as skeletal and cardiac muscle can be imaged by using an objective-based probe in the tissue and scanning at a sufficiently fast rate to mitigate motion artifacts due to physiological motion. According to one example embodiment, such a probe is part of a system that is capable of reverse-direction high-resolution imaging without needing to stain or otherwise introduce a foreign element used to generate or otherwise increase the sensed light. The probe can include a light generator for generating light pulses that are directed towards structures located within the thick tissue. The system can additionally include aspects that lessen adverse image-quality degradation. Further, the system can additionally be constructed as a hand-held device.Type: ApplicationFiled: September 27, 2019Publication date: April 2, 2020Inventors: Gabriel Nestor Sanchez, Scott L. Delp, Mark J. Schnitzer, Michael E. Llewellyn
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Patent number: 10583309Abstract: A variety of methods, devices, systems and arrangements are implemented for stimulation of the peripheral nervous system. Consistent with one embodiment of the present invention, method is implemented in which light-responsive channels or pumps are engineered in a set of motor units that includes motor units of differing physical volumes. Optical stimuli are also provided to the light-responsive channels or pumps at an optical intensity that is a function of the size of motor units to be recruited. In certain implementations, the intensity of the optical stimuli is increased so as to recruit increasingly larger motor units.Type: GrantFiled: November 14, 2016Date of Patent: March 10, 2020Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Karl A. Deisseroth, Scott L. Delp, Michael E. Llewellyn, Christine A. McLeavey Payne
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Patent number: 10561839Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: GrantFiled: January 14, 2019Date of Patent: February 18, 2020Assignee: Cala Health, Inc.Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Patent number: 10549093Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: GrantFiled: January 8, 2019Date of Patent: February 4, 2020Assignee: Cala Health, Inc.Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Patent number: 10499797Abstract: Biological tissue such as skeletal and cardiac muscle can be imaged by using an objective-based probe in the tissue and scanning at a sufficiently fast rate to mitigate motion artifacts due to physiological motion. According to one example embodiment, such a probe is part of a system that is capable of reverse-direction high-resolution imaging without needing to stain or otherwise introduce a foreign element used to generate or otherwise increase the sensed light. The probe can include a light generator for generating light pulses that are directed towards structures located within the thick tissue. The system can additionally include aspects that lessen adverse image-quality degradation. Further, the system can additionally be constructed as a hand-held device.Type: GrantFiled: November 18, 2014Date of Patent: December 10, 2019Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Gabriel Nestor Sanchez, Scott L. Delp, Mark J. Schnitzer, Michael E. Llewellyn
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Patent number: 10307609Abstract: The present disclosure provides compositions and methods for controlling pain. The present disclosure provides methods for identifying agents that control pain.Type: GrantFiled: August 13, 2014Date of Patent: June 4, 2019Assignees: The Board of Trustees of the Leland Stanford Junior University, Circuit Therapeutics, Inc.Inventors: Shrivats Mohan Iyer, Scott L. Delp, Kathryn L. Montgomery, Karl A. Deisseroth, Christopher Towne
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Publication number: 20190143111Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: ApplicationFiled: January 8, 2019Publication date: May 16, 2019Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Publication number: 20190143113Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: ApplicationFiled: January 14, 2019Publication date: May 16, 2019Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein
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Publication number: 20190083573Abstract: The present disclosure provides a method for modulating pain in a subject comprising activating an exogenous receptor expressed in a target neuron with an effective amount of an agent that specifically activates the exogenous receptor. The present disclosure provides a method for modulating the activity of a neuron comprising activating an exogenous receptor expressed in the neuron by contacting the neuron with an agent that specifically activates the exogenous receptor. The present disclosure provides a method of screening to identify compounds that modulate pain.Type: ApplicationFiled: January 25, 2017Publication date: March 21, 2019Inventors: Shrivats Mohan Iyer, Scott L. Delp
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Patent number: 10179238Abstract: A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.Type: GrantFiled: September 29, 2017Date of Patent: January 15, 2019Assignee: Cala Health, Inc.Inventors: Serena HanYing Wong, Kathryn H. Rosenbluth, Samuel Hamner, Paula Chidester, Scott L. Delp, Terence D. Sanger, David Klein