Patents by Inventor Scott L. Nyberg

Scott L. Nyberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioartificial liver
    Patent number: 10792410
    Abstract: This document provides bioartificial liver (BAL) devices. Methods for making and using BAL devices also are provided.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: October 6, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Scott L. Nyberg, Stephen M. Corner, Bruce Amiot
  • Bioartificial Liver
    Publication number: 20190184086
    Abstract: This document provides bioartificial liver (BAL) devices. Methods for making and using BAL devices also are provided.
    Type: Application
    Filed: October 25, 2018
    Publication date: June 20, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Scott L. Nyberg, Stephen M. Corner, Bruce Amiot
  • Bioartificial liver
    Patent number: 10130748
    Abstract: This document provides bioartificial liver (BAL) devices. Methods for making and using BAL devices also are provided.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: November 20, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Scott L. Nyberg, Stephen M. Corner, Bruce Amiot
  • Bioartificial liver system
    Patent number: 9650609
    Abstract: A bioartificial liver system is described that incorporates a cell reservoir and hepatocyte spheroids to both increase the number of and longevity of cells in the system. Additional methods are also described for forming spheroid aggregates from isolated hepatocytes.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: May 16, 2017
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Scott L. Nyberg
  • BIOARTIFICIAL LIVER SYSTEM
    Publication number: 20140295548
    Abstract: A bioartificial liver system is described that incorporates a cell reservoir and hepatocyte spheroids to both increase the number of and longevity of cells in the system. Additional methods are also described for forming spheroid aggregates from isolated hepatocytes.
    Type: Application
    Filed: June 17, 2014
    Publication date: October 2, 2014
    Inventor: Scott L. Nyberg
  • Method for treating blood or plasma using hepatocyte spheroids
    Patent number: 8785117
    Abstract: A bioartificial liver system is described that incorporates a cell reservoir and hepatocyte spheroids to both increase the number of and longevity of cells in the system. Additional methods are also described for forming spheroid aggregates from isolated hepatocytes.
    Type: Grant
    Filed: November 21, 2006
    Date of Patent: July 22, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Scott L Nyberg
  • BIOARTIFICIAL LIVER
    Publication number: 20120009086
    Abstract: This document provides bioartificial liver (BAL) devices. Methods for making and using BAL devices also are provided.
    Type: Application
    Filed: March 12, 2010
    Publication date: January 12, 2012
    Inventors: Scott L. Nyberg, Stephen M. Corner, Bruce Amiot
  • BIOARTIFICIAL LIVER SYSTEM
    Publication number: 20080166808
    Abstract: A bioartificial liver system is described that incorporates a cell reservoir and hepatocyte spheroids to both increase the number of and longevity of cells in the system. Additional methods are also described for forming spheroid aggregates from isolated hepatocytes.
    Type: Application
    Filed: November 21, 2006
    Publication date: July 10, 2008
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Scott L. Nyberg
  • Bioartificial liver system
    Patent number: 7160719
    Abstract: A bioartificial liver system is described that incorporates a cell reservoir and hepatocyte spheroids to both increase the number of and longevity of cells in the system. Additional methods are also described for forming spheroid aggregates from isolated hepatocytes.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: January 9, 2007
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Scott L. Nyberg
  • Bioartificial liver system
    Publication number: 20030228685
    Abstract: A bioartificial liver system is described that incorporates a cell reservoir and hepatocyte spheroids to both increase the number of and longevity of cells in the system. Additional methods are also described for forming spheroid aggregates from isolated hepatocytes.
    Type: Application
    Filed: June 7, 2002
    Publication date: December 11, 2003
    Inventor: Scott L. Nyberg
  • Bioreactor device with application as a bioartificial liver
    Patent number: 5605835
    Abstract: A bioreactor apparatus comprising two chambers, a feed and waste chamber and a cell chamber separated by a selectively permeable membrane. Within the cell chamber, a biocompatible three-dimensional matrix entraps animal cells or genetic modifications thereof. Due to the presence of this biocompatible matrix, the cell chamber generally has a gel phase, i.e., the biocompatible matrix and cells, and a liquid phase containing a concentrated solution of the cell product to be harvested. Thus, the bioreactor of this invention uses only two chambers to achieve three distinct zones within the apparatus. A bioartificial liver is based on a bioreactor of the type having two fluid paths separated by a permeable medium. The bioreactor can be of either hollow fiber or flat-bed configuration. In the configuration using hollow fibers, the two fluid paths correspond to the cavity surrounding the hollow fibers (the extracapillary space), and to the lumens of the hollow fibers themselves.
    Type: Grant
    Filed: January 20, 1995
    Date of Patent: February 25, 1997
    Assignee: Regents of the University of Minnesota
    Inventors: Wei-Shou Hu, Frank B. Cerra, Scott L. Nyberg, Matthew T. Scholz, Russell A. Shatford