Abstract: Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2, L, W1, W2, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and/or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.

Abstract: The present disclosure relates to compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

Abstract: Method and apparatus for aligning one end of an optical fiber in the emitting well of an LED employs an elongated rod having a flat milled halfway through the mid-section thereof for forming a recess and first and second channels extending between the recess and an associated end of the rod to the depth of the recess. The two channels are located in front of the bottom of the recess and are oriented at 90.degree. with respect to each other in an end view. The channels also overlap along the center line of the rod and are dimensioned for loosely-releasably receiving and supporting a length of fiber in a straight line while the one end thereof is aligned with the emitting surface of the LED.