Abstract: Provided herein are engineered hMPV F proteins. In some aspects, the engineered F proteins exhibit enhanced conformational stability and/or antigenicity. Methods are also provided for use of the engineered F proteins as diagnostics, in screening platforms, and/or in vaccine compositions.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that modify digital images via scene-based editing using image understanding facilitated by artificial intelligence. For example, in one or more embodiments the disclosed systems utilize generative machine learning models to create modified digital images portraying human subjects. In particular, the disclosed systems generate modified digital images by performing infill modifications to complete a digital image or human inpainting for portions of a digital image that portrays a human. Moreover, in some embodiments, the disclosed systems perform reposing of subjects portrayed within a digital image to generate modified digital images. In addition, the disclosed systems in some embodiments perform facial expression transfer and facial expression animations to generate modified digital images or animations.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that modify digital images via multi-layered scene completion techniques facilitated by artificial intelligence. For instance, in some embodiments, the disclosed systems receive a digital image portraying a first object and a second object against a background, where the first object occludes a portion of the second object. Additionally, the disclosed systems pre-process the digital image to generate a first content fill for the portion of the second object occluded by the first object and a second content fill for a portion of the background occluded by the second object. After pre-processing, the disclosed systems detect one or more user interactions to move or delete the first object from the digital image. The disclosed systems further modify the digital image by moving or deleting the first object and exposing the first content fill for the portion of the second object.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that modify digital images via scene-based editing using image understanding facilitated by artificial intelligence. For example, in one or more embodiments the disclosed systems utilize generative machine learning models to create modified digital images portraying human subjects. In particular, the disclosed systems generate modified digital images by performing infill modifications to complete a digital image or human inpainting for portions of a digital image that portrays a human. Moreover, in some embodiments, the disclosed systems perform reposing of subjects portrayed within a digital image to generate modified digital images. In addition, the disclosed systems in some embodiments perform facial expression transfer and facial expression animations to generate modified digital images or animations.

Abstract: The invention relates to imidazopyridines of Formula (I) and pharmaceutically acceptable salts thereof, wherein R0 to R5 are as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The benzimidazoles of Formula (I) are ITK inhibitors and are therefore potentially useful in the treatment of a wide range of disorders including, atopic dermatitis.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for panoptically guiding digital image inpainting utilizing a panoptic inpainting neural network. In some embodiments, the disclosed systems utilize a panoptic inpainting neural network to generate an inpainted digital image according to panoptic segmentation map that defines pixel regions corresponding to different panoptic labels. In some cases, the disclosed systems train a neural network utilizing a semantic discriminator that facilitates generation of digital images that are realistic while also conforming to a semantic segmentation. The disclosed systems generate and provide a panoptic inpainting interface to facilitate user interaction for inpainting digital images. In certain embodiments, the disclosed systems iteratively update an inpainted digital image based on changes to a panoptic segmentation map.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for panoptically guiding digital image inpainting utilizing a panoptic inpainting neural network. In some embodiments, the disclosed systems utilize a panoptic inpainting neural network to generate an inpainted digital image according to panoptic segmentation map that defines pixel regions corresponding to different panoptic labels. In some cases, the disclosed systems train a neural network utilizing a semantic discriminator that facilitates generation of digital images that are realistic while also conforming to a semantic segmentation. The disclosed systems generate and provide a panoptic inpainting interface to facilitate user interaction for inpainting digital images. In certain embodiments, the disclosed systems iteratively update an inpainted digital image based on changes to a panoptic segmentation map.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for panoptically guiding digital image inpainting utilizing a panoptic inpainting neural network. In some embodiments, the disclosed systems utilize a panoptic inpainting neural network to generate an inpainted digital image according to panoptic segmentation map that defines pixel regions corresponding to different panoptic labels. In some cases, the disclosed systems train a neural network utilizing a semantic discriminator that facilitates generation of digital images that are realistic while also conforming to a semantic segmentation. The disclosed systems generate and provide a panoptic inpainting interface to facilitate user interaction for inpainting digital images. In certain embodiments, the disclosed systems iteratively update an inpainted digital image based on changes to a panoptic segmentation map.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for panoptically guiding digital image inpainting utilizing a panoptic inpainting neural network. In some embodiments, the disclosed systems utilize a panoptic inpainting neural network to generate an inpainted digital image according to panoptic segmentation map that defines pixel regions corresponding to different panoptic labels. In some cases, the disclosed systems train a neural network utilizing a semantic discriminator that facilitates generation of digital images that are realistic while also conforming to a semantic segmentation. The disclosed systems generate and provide a panoptic inpainting interface to facilitate user interaction for inpainting digital images. In certain embodiments, the disclosed systems iteratively update an inpainted digital image based on changes to a panoptic segmentation map.

Abstract: Techniques and systems are provided for training a machine learning model using different datasets to perform one or more tasks. The machine learning model can include a first sub-module configured to perform a first task and a second sub-module configured to perform a second task. The first sub-module can be selected for training using a first training dataset based on a format of the first training dataset. The first sub-module can then be trained using the first training dataset to perform the first task. The second sub-module can be selected for training using a second training dataset based on a format of the second training dataset. The second sub-module can then be trained using the second training dataset to perform the second task.

Abstract: A system and method for creating, managing, and displaying 3D digital collectibles comprising a virtual, three dimensional, n-sided structure including a digital media file or set of digital media files representing an event rendered on a representation of at least a first surface thereof, and data relating to the event rendered on at least a second surface thereof and other content on one or more other surfaces, where the digital media file may be video clip of the event that can be played automatically via a media player associated with the display.

Abstract: Provided herein are engineered hMPV F proteins. In some aspects, the engineered F proteins exhibit enhanced conformational stability and/or antigenicity. Methods are also provided for use of the engineered F proteins as diagnostics, in screening platforms, and/or in vaccine compositions.

Abstract: A system includes a logic device configured to cause the system to perform operations. The operations include requesting, from a peripheral device coupled to a host device, a device descriptor of the peripheral device, receiving, from the peripheral device, the device descriptor including at least two configurations. A first configuration includes an audio communications protocol having a plurality of selectable audio bit-rates and a second configuration including a plurality of selectable audio bit-rates and burst-rates. The operations further include selecting, from the first configuration and the second configuration based, at least in part, on a configuration of the host device, wherein the host device is configured to select the second configuration when the host device is compatible with the second configuration and select the first configuration when the host device is not compatible with the second configuration.

Abstract: A combined type AC/DC power supply includes a first circuit module containing a first printed circuit board (PCB), an AC power input circuit being set on the first PCB, a first structural portion of a detachable bobbin being set on the first PCB, a primary side winding being wound around the first structural portion of the detachable bobbin and electrically connected to the first PCB and the AC power input circuit, a second circuit module containing a second PCB, a DC power output circuit being set on the second PCB, a second structural portion of the detachable bobbin being set on the second PCB with a secondary side winding being wound around and electrically connected to the second PCB and the DC power output circuit, wherein the AC and the DC power output circuit are structurally connected through the first and the second structural portion of the detachable bobbin.

Abstract: A rules based software user interface application and environment, comprising: a) a clinical quality measure library database schema, b) a clinical quality measure specification database schema, c) a rules library, d) a clinical business rule (CBR) editor, e) a key performance indicator (KPI) or clinical quality measure specification editor, f) a clinical quality runtime configuration module, g) a cost of care runtime configuration module and h) a runtime manager module and, in some embodiments, i) a measure testing module. In some embodiments, rules-based software applications comprise a component for delivery of clinical measure description libraries as a web or Internet application. In other embodiments, rules-based software applications comprise a component for measure testing which include a test data generator module which generates a test database with a known target measure result and an audit detail component for inspecting test results.

Abstract: A circuit for automatically resetting a central processing unit (CPU) is provided. The circuit includes a detector and a reset signal generator. The detector is electrically connected to the CPU for receiving a specified signal from the CPU, and the detector sends out a triggering signal when the specified signal is not received for a predetermined period of time. The reset signal generator is electrically connected to the detector for generating a reset signal in response to the triggering signal. A chipset with a reset completion indication function is also provided. The chipset includes a plurality of functional circuits and a calculating and recording device.

Abstract: A voltage level detector for use between a power supply apparatus and a functional circuit is provided. The voltage level detector includes a power input terminal, a voltage dividing circuit and a logic operation circuit. The power input terminal is used for receiving power of a first voltage. The voltage dividing circuit is used for dividing the first voltage into a second voltage having a level lower than that of the first voltage but greater than a threshold voltage. The logic operation circuit is integrated with the functional circuit and having a first and a second input ends thereof electrically connected to the power input terminal and the voltage dividing circuit, respectively. According to the voltage level detector of the present invention, a warning signal is asserted to the functional circuit when the second voltage level drops below the threshold voltage.

Abstract: A voltage level detector for use between a power supply apparatus and a functional circuit is provided. The voltage level detector includes a power input terminal, a voltage dividing circuit and a logic operation circuit. The power input terminal is used for receiving power of a first voltage. The voltage dividing circuit is used for dividing the first voltage into a second voltage having a level lower than that of the first voltage but greater than a threshold voltage. The logic operation circuit is integrated with the functional circuit and having a first and a second input ends thereof electrically connected to the power input terminal and the voltage dividing circuit, respectively. According to the voltage level detector of the present invention, a warning signal is asserted to the functional circuit when the second voltage level drops below the threshold voltage.

Abstract: A circuit for automatically resetting a central processing unit (CPU) is provided. The circuit includes a detector and a reset signal generator. The detector is electrically connected to the CPU for receiving a specified signal from the CPU, and the detector sends out a triggering signal when the specified signal is not received for a predetermined period of time. The reset signal generator is electrically connected to the detector for generating a reset signal in response to the triggering signal. A chipset with a reset completion indication function is also provided. The chipset includes a plurality of functional circuits and a calculating and recording device.

Abstract: A system that integrates the function of a computer input/output integrated circuit (IC) and a smart card reader. The integrated system includes a computer input/output IC and a reading device. The system is capable of eliminating interface problems resulting from non-standardized hardware in addition to a reduction in production cost and an improvement in working stability.