Abstract: The inventive coating may be employed to deliver a pharmaceutical agent to a selected body area that is involved within the insertion or application of a medical device. Such medical devices may include silicone based urinary catheters and other medical implants as well as other silicone based devices having deformable portions which could benefit from the release of a pharmaceutical agent from its surface. The coating allows the introduction of the pharmacological additive having a release rate that is within acceptable pharmacokinetic criteria. The release rate is adjusted by utilizing different salt forms of the additive and adjusting the concentration of urethane and RTV silicone. The coating incorporates additive compounds such as anti-microbial, anti-fungals and other organic compounds. Methods are also provided for the manufacture of the subject coating and for the application of the same to surfaces of medical devices.

Abstract: The inventive coating may be employed to deliver a pharmaceutical agent to a selected body area that is involved within the insertion or application of a medical device. Such medical devices may include silicone based urinary catheters and other medical implants as well as other silicone based devices having deformable portions which could benefit from the release of a pharmaceutical agent from its surface. The coating allows the introduction of the pharmacological additive having a release rate that is within acceptable pharmacokinetic criteria. The release rate is adjusted by utilizing different salt forms of the additive and adjusting the concentration of urethane and RTV silicone. The coating incorporates additive compounds such as anti-microbial, anti-fungals and other organic compounds. Methods are also provided for the manufacture of the subject coating and for the application of the same to surfaces of medical devices.

Abstract: A wound dressing comprises a vapor permeable plastic film coated on one side with an adhesive about the periphery of a wound contacting window in the central portion of the dressing. A pair of release liners covers the adhesive coating and include tabs so that the release liners can be peeled from the adhesive coating. Strips are provided adjacent to and at opposite lateral sides of the wound contacting window to change abruptly the resistance to peeling of the release liners from the adhesive coated film. Accordingly, when the user feels this change in resistance, he or she knows that the wound contacting window and a small portion of the adhesive about the periphery thereof is uncovered which allows the dressing to be anchored about the patient's wound with the release liners partially in place and the wound contacting window exposed. This minimizes the tendency of the film to wrinkle and/or to fold on itself such that the adhesive adheres to itself.

Abstract: A wound dressing comprises a vapor permeable plastic film coated on one side with an adhesive about the periphery of a wound contacting window in the central portion of the dressing. A pair of release liners covers the adhesive coating and include tabs so that the release liners can be peeled from the adhesive coating. Means are provided adjacent to and at opposite lateral sides of the wound contacting window to change abruptly the resistance to peeling of the release liners from the adhesive coated film. Accordingly, when the user feels this change in resistance, he or she knows that the wound contacting window and a small portion of the adhesive about the periphery thereof is uncovered which allows the dressing to be anchored about the patient's wound with the release liners partially in place and the wound contacting window exposed. This minimizes the tendency of the film to wrinkle and/or to fold on itself such that the adhesive adheres to itself.