Abstract: Described herein is the design and construction of a class of lipoprotein targeting protease inhibitors. Small peptides with protease inhibitor activity are conjugated to hydrophobic, lipoprotein targeting molecules using, for instance, amine reactive chemistry. Methods of use of the resultant lipoprotein targeting protease inhibitor (antiprotease) molecules are also described. Also described is the production and use of protease inhibitor enriched HDL particles, as well as A1AT-peptide-enriched HDL particles, and their use in various therapeutic contexts.

Abstract: Described herein is the design and construction of a class of lipoprotein targeting protease inhibitors. Small peptides with protease inhibitor activity are conjugated to hydrophobic, lipoprotein targeting molecules using, for instance, amine reactive chemistry. Methods of use of the resultant lipoprotein targeting protease inhibitor (antiprotease) molecules are also described. Also described is the production and use of protease inhibitor enriched HDL particles, as well as AlAT-peptide-enriched HDL particles, and their use in various therapeutic contexts.

Abstract: Described herein is the design and construction of a class of lipoprotein targeting protease inhibitors. Small peptides with protease inhibitor activity are conjugated to hydrophobic, lipoprotein targeting molecules using, for instance, amine reactive chemistry. Methods of use of the resultant lipoprotein targeting protease inhibitor (antiprotease) molecules are also described. Also described is the production and use of protease inhibitor enriched HDL particles, as well as A1AT-peptide-enriched HDL particles, and their use in various therapeutic contexts.

Abstract: A sensor for measuring displacement and time comprises a hollow body including a longitudinal axis. The hollow body comprises a wall including an inner surface and an outer surface, and a pathway defined by the inner surface. The sensor further comprises a solid body including an outer surface, the solid body configured to be received by the hollow body and travel through the pathway. The sensor further comprises a plurality of frangible wires, where each wire of the plurality of wires extends through a first opening in the wall, across the pathway, and through a second opening in the wall, and each wire is spaced apart by a distance in a direction generally parallel to the longitudinal axis of the hollow body.

Abstract: A sensor for measuring displacement and time comprises a hollow body including a longitudinal axis. The hollow body comprises a wall including an inner surface and an outer surface, and a pathway defined by the inner surface. The sensor further comprises a solid body including an outer surface, the solid body configured to be received by the hollow body and travel through the pathway. The sensor further comprises a plurality of frangible wires, where each wire of the plurality of wires extends through a first opening in the wall, across the pathway, and through a second opening in the wall, and each wire is spaced apart by a distance in a direction generally parallel to the longitudinal axis of the hollow body.

Abstract: Described herein is the design and construction of a class of lipoprotein targeting protease inhibitors. Small peptides with protease inhibitor activity are conjugated to hydrophobic, lipoprotein targeting molecules using, for instance, amine reactive chemistry. Methods of use of the resultant lipoprotein targeting protease inhibitor (antiprotease) molecules are also described. Also described is the production and use of protease inhibitor enriched HDL particles, as well as A1AT-peptide-enriched HDL particles, and their use in various therapeutic contexts.

Abstract: A modular cart for use with an anthropomorphic test device, an assembly including an anthropomorphic test device and a method of placing an anthropomorphic test device on a modular cart. The cart includes a wheeled base with a pair of upstanding posts that together with members that can be interchangeably secured to one of the posts in order to form one of a storage position or a ready-to-test position. In this way, when an anthropomorphic test device is placed on the cart between these members, the members and the posts cooperate with one another to have the anthropomorphic test device be in a generally seating position that can accommodate both storage and testing without having to reposition the anthropomorphic test device.

Abstract: A modular cart for use with an anthropomorphic test device, an assembly including an anthropomorphic test device and a method of placing an anthropomorphic test device on a modular cart. The cart includes a wheeled base with a pair of upstanding posts that together with members that can be interchangeably secured to one of the posts in order to form one of a storage position or a ready-to-test position. In this way, when an anthropomorphic test device is placed on the cart between these members, the members and the posts cooperate with one another to have the anthropomorphic test device be in a generally seating position that can accommodate both storage and testing without having to reposition the anthropomorphic test device.

Abstract: Described herein is the design and construction of a class of lipoprotein targeting protease inhibitors. Small peptides with protease inhibitor activity are conjugated to hydrophobic, lipoprotein targeting molecules using, for instance, amine reactive chemistry. Methods of use of the resultant lipoprotein targeting protease inhibitor (antiprotease) molecules are also described. Also described is the production and use of protease inhibitor enriched HDL particles, as well as A1AT-peptide-enriched HDL particles, and their use in various therapeutic contexts.