Abstract: Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally, provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Abstract: Embodiments of the present disclosure provided herein include methods, computer readable mediums, apparatus, and systems for facilitating diagnosis and repair of one or more performance states associated with a computing device.

Abstract: Embodiments of the present disclosure provide for predicted operational support data object selection and provision functionality. Predicted operational support data object(s) may be selected and provided to address particular malfunction classification(s) affecting networked device(s) on a dynamic home communications network. Some embodiments include identifying, in real-time, a device identification data set associated with a networked device set communicable with the dynamic home communications network; retrieving a device activity data set associated with the networked device set; applying a malfunction classification data model to the device activity data set to select the predicted operational support data object from the device operational support management repository; and outputting the predicted operational support data object to a client device in communication with the dynamic home communications network.

Abstract: A system, method, and computer program product for identifying location-specific faults are provided. Some embodiments may include receiving first device status data associated with a first computing device and the first device status data may comprise first location-indicative data indicative of a location. Some embodiments may include comparing the first device status data with second device status data associated with one or more second computing devices and the second device status data may comprise second location-indicative data indicative of the location. In some embodiments, based on the comparison of the first device status data and the second device status data, determining that the first computing device is affected by one or more of a device-specific fault or a location-specific fault. Some embodiments may include causing information regarding the device-specific fault or the location-specific fault to be displayed via a graphical user interface.

Abstract: Embodiments of the present disclosure provided herein include methods, computer readable mediums, apparatus, and systems for facilitating diagnosis and repair of one or more performance states associated with a computing device.

Abstract: A power meter for a bicycle includes a body having a torque input section and a torque output section, the body configured to transmit power between the torque input section and the torque output section. The power meter also includes a printed circuit board (“PCB”) having a substrate and at least one strain measurement device which may be attached to the PCB. The power meter may be integrally constructed with a chainring construction.

Abstract: A power meter for a bicycle includes a body having a torque input section and a torque output section, the body configured to transmit power between the torque input section and the torque output section. The power meter also includes a printed circuit board (“PCB”) having a substrate and at least one strain measurement device which may be attached to the PCB. The power meter may be integrally constructed with a chainring construction.

Abstract: A chainring structure may include a torque output section comprising a plurality of sprockets having two axially bounding sprockets defining an inner-most and outer-most sprocket and a torque input section configured to attach to a crank assembly. The chainring structure may also include a power meter chamber disposed radially between the torque input section and the torque output section, the power meter chamber including a base surface of a strain measurement section. The power meter may be disposed in the power meter chamber and have at least one strain measurement device attached to the base surface. The torque output section, torque input section, and power meter chamber may be formed as a unitary single piece and configured to dispose the base surface axially between the axially bounding sprockets of the plurality of sprockets.

Abstract: A power meter for a bicycle includes a body having a torque input section and a torque output section, the body configured to transmit power between the torque input section and the torque output section. The power meter also includes a printed circuit board (“PCB”) having a substrate and at least one strain measurement device which may be attached to the PCB. The power meter may be integrally constructed with a chainring construction.

Abstract: A bicycle shifter configured to be adjustable to accommodate a variety of sized hands. The shifter includes a housing, a cable spool for pulling and releasing a control cable, pull and cable release lever mechanisms and a clamp for mounting the shifter to a handlebar. The cable pull lever mechanism includes a cable pull lever and a driver element operatively connected to the cable spool. The release mechanism includes a cable release lever. The cable pull lever is attachable to the driver element at various orientations to vary the position of the cable pull lever relative to the cable release lever. The clamp is attachable to the shifter housing at different positions to vary the pull and cable release levers relative to the handgrip element on the handlebar.

Abstract: A method for providing environmental monitoring of an item with an electronic system includes the steps of operating the electronic system in a deep-sleep mode at a minimal level of power consumption by disabling operation of nonessential portions of the electronic system; activating the electronic system at a monitoring rate to sense an environmental parameter to which the item is subjected; sensing a value of the environmental parameter to which the item is subjected; comparing the sensed environmental parameter with the value of the environmental parameter just previously sensed to derive a rate of change of the environmental parameter; adjusting the monitoring rate to track the rate of change of the environmental parameter; storing the value of the sensed environmental parameter; and returning the electronic system to the deep-sleep mode.

Abstract: An apparatus provides environmental monitoring of an item and includes an RFID tag, and a passive switch for sensing an environmental parameter to which the item is subjected, and coupled to the RFID tag so that a measurement of the sensed environmental parameter can be stored, the RFID tag for providing remote readout of the sensed environmental parameter. A method provides environmental monitoring of an item and includes the steps of sensing an environmental parameter to which the item is subjected with activation of a passive switch, storing a measurement of the sensed environmental parameter upon the event of activation of the passive switch, and providing remote readout of the measurement of the sensed environmental parameter with an RFID tag.

Abstract: A literature on demand (LOD) distribution system comprises a secure server hosting a LOD database and a vendor's electronic data processing device on which a LOD application is loaded. The vendor's electronic data processing device is configured to execute the LOD application to perform operations including: storing a local LOD database containing a portion or all of the LOD items stored in the LOD database at the secure server; selecting an LOD item stored in the local LOD database; displaying the selected LOD item or causing the selected LOD item to be displayed by a viewer application executing on the electronic data processing device; constructing an email including a hyperlink for downloading or streaming the selected LOD item from the LOD database of the secure server; and sending the constructed email to a recipient or causing the constructed email to be sent to the recipient by an email application executing on the electronic data processing device.

Abstract: A mounting device is shown for mounting components to a bicycle handlebar having a handlebar axis. The mounting device includes a mounting bracket mountable to the handlebar about the handlebar axis. The mounting bracket includes a first clamp portion and a second clamp portion hingedly connected to the first clamp portion to interiorly receive the handlebar. An interior channel is defined by spaced sidewalls and formed in a portion of the circumferential length of one of the first and second clamp portions, and a hole is formed through the clamp portion and opens to the channel.

Abstract: A mounting device for mounting first and second bicycle control components to a bicycle handlebar having a handlebar axis. The mounting device generally includes first and second mounting brackets. The first mounting bracket is adjustably mounted to the handlebar about the handlebar axis. One of the first and second bicycle control components is attached to the first mounting bracket. The second mounting bracket is adjustably attached to the first mounting bracket. The other of the first and second bicycle control components is attached to the second mounting bracket. The second mounting bracket is displaced between alternative attachment positions on the first mounting bracket. The first mounting bracket is rotated between alternative mounting positions on the handlebar.

Abstract: A mounting device for mounting first and second bicycle control components to a bicycle handlebar having a handlebar axis. The mounting device generally includes first and second mounting brackets. The first mounting bracket is adjustably mounted to the handlebar about the handlebar axis. One of the first and second bicycle control components is attached to the first mounting bracket. The second mounting bracket is adjustably attached to the first mounting bracket. The other of the first and second bicycle control components is attached to the second mounting bracket. The second mounting bracket is displaced between alternative attachment positions on the first mounting bracket. The first mounting bracket is rotated between alternative mounting positions on the handlebar.

Abstract: A mounting device is shown for mounting components to a bicycle handlebar having a handlebar axis. The mounting device includes a mounting bracket mountable to the handlebar about the handlebar axis. The mounting bracket includes a first clamp portion and a second clamp portion hingedly connected to the first clamp portion to interiorly receive the handlebar. An interior channel is defined by spaced sidewalls and formed in a portion of the circumferential length of one of the first and second clamp portions, and a hole is formed through the clamp portion and opens to the channel.

Abstract: An apparatus provides environmental monitoring of an item and includes an RFID tag, and a passive switch for sensing an environmental parameter to which the item is subjected, and coupled to the RFID tag so that a measurement of the sensed environmental parameter can be stored, the RFID tag for providing remote readout of the sensed environmental parameter. A method provides environmental monitoring of an item and includes the steps of sensing an environmental parameter to which the item is subjected with activation of a passive switch, storing a measurement of the sensed environmental parameter upon the event of activation of the passive switch, and providing remote readout of the measurement of the sensed environmental parameter with an RFID tag.

Abstract: A trigger shifter for operating a bicycle gear change device that includes a housing mountable to handlebar, a cable spool for pulling and releasing a control cable connected to the gear change device, a pull lever mechanism and a release lever mechanism. The pull lever mechanism includes a pull lever rotatable about a first axis defining a first plane of motion perpendicular to the first axis. The release lever mechanism includes a release lever rotatable about a second axis defining a second plane of motion perpendicular to the second axis. The first and second planes of motion form an angle therebetween in the range of 20 to 70 degrees.

Abstract: The invention relates to a trigger shifter with virtually no takeup distance during the takeup process. In its original position, the takeup pawl is located in the immediate vicinity of the transport tooth set, such that the takeup pawl and takeup lever do not need to cover a takeup distance. In the release process, the takeup pawl, which is in the ready position to engage, is moved out of the region of the transport tooth set by means of a connecting link, preferably a shackle spring, and subsequently the retaining pawl is disengaged so that so that the cable coil can be rotated by the prestressed cable pull without any obstacles. In addition to its function of controlling the takeup pawl, the shackle spring can also provide initial tension in the retaining direction to the sliding element with the retaining pawl.