Patents by Inventor Scott Newland
Scott Newland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12098434Abstract: Provided herein is a method for detecting the presence of a COVID-19 virus in a human sample or an environmental sample having one or more viral and bacterial pathogens. Samples processed to obtain total nucleic acids. The nucleic acids are used as a template in a reverse transcription-amplification reaction to obtain cDNA, which is used in a PCR amplification reaction to obtain fluorescent COVID-19 virus specific amplicons. These amplicons are detected by microarray hybridization near the lowest limit of detection. Also provided is a method for detecting in addition to the COVID-19 virus, the presence of respiratory disease-causing pathogens including viruses, bacteria and fungus in a single assay using the above method.Type: GrantFiled: November 17, 2020Date of Patent: September 24, 2024Assignee: PathogenDx, Inc.Inventors: Michael Edward Hogan, Benjamin Alan Katchman, Frederick Henry Eggers, Cory Scott Newland
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Patent number: 11920188Abstract: Provided herein is a method for detecting the presence of clade variants in the COVID-19 virus in a human sample and/or an environmental sample. Samples are processed to obtain total RNA. The RNA is used as a template in a combined reverse transcription and amplification reaction to obtain fluorescent COVID-19 virus amplicons. These amplicons are hybridized on a microarray with nucleic acid probes having sequences that discriminate among the various clade variants. The microarray is imaged to detect the clade variant. Also provided is a method of distinguishing each clade variant from others by generating an intensity distribution profile from the image, which is unique to each of the clade variants.Type: GrantFiled: May 27, 2021Date of Patent: March 5, 2024Inventors: Frederick Henry Eggers, Benjamin Alan Katchman, Fushi Wen, Candy Mavis Rivas, Cory Scott Newland, Michael Edward Hogan
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Patent number: 11702709Abstract: Provided herein is a method for detecting the presence of clade variants in the COVID-19 virus in a human sample and/or an environmental sample. Samples are processed to obtain total RNA. The RNA is used as a template in a combined reverse transcription and amplification reaction to obtain fluorescent COVID-19 virus amplicons. These amplicons are hybridized on a microarray with nucleic acid probes having sequences that discriminate among the various clade variants. The microarray is imaged to detect the clade variant and each clade variant is distinguished from others by generating an intensity distribution profile from the image, which is unique to each of the clade variants.Type: GrantFiled: November 18, 2021Date of Patent: July 18, 2023Assignee: PathogenDx, Inc.Inventors: Frederick Henry Eggers, Benjamin Alan Katchman, Fushi Wen, Candy Mavis Rivas, Cory Scott Newland, Michael Edward Hogan
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Publication number: 20220364157Abstract: Provided herein is a method for detecting the presence of a COVID-19 virus in a human sample or an environmental sample having one or more viruses and bacterial pathogens. Samples are processed to obtain total nucleic acids. A combined reverse transcription and asymmetric PCR amplification reaction is performed to obtain fluorescent labeled COVID-19 virus specific amplicons. The amplicons are detected by microarray hybridization near the lowest limit of detection. Also provided is a method for detecting concurrently with COVID-19 virus, the presence of respiratory disease-causing pathogens including viruses, bacteria and fungus in a single assay using the above method.Type: ApplicationFiled: November 17, 2020Publication date: November 17, 2022Applicant: PathogenDx, Inc.Inventors: Michael Edward Hogan, Benjamin Alan Katchman, Frederick Henry Eggers, Cory Scott Newland
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Publication number: 20220267829Abstract: Provided herein is a method for detecting the presence of clade variants in the COVID-19 virus in a human sample and/or an environmental sample. Samples are processed to obtain total RNA. The RNA is used as a template in a combined reverse transcription and amplification reaction to obtain fluorescent COVID-19 virus amplicons. These amplicons are hybridized on a microarray with nucleic acid probes having sequences that discriminate among the various clade variants. The microarray is imaged to detect the clade variant and each clade variant is distinguished from others by generating an intensity distribution profile from the image, which is unique to each of the clade variants. Also provided are methods for detecting and genotyping SARS-CoV-2.Type: ApplicationFiled: February 22, 2022Publication date: August 25, 2022Applicant: PathogenDx, Inc.Inventors: Frederick Henry Eggers, Benjamin Alan Katchman, Fushi Wen, Candy Mavis Rivas, Cory Scott Newland, Michael Edward Hogan
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Publication number: 20220267867Abstract: Provided herein is a method for detecting the presence of clade variants in the COVID-19 virus in a human sample and/or an environmental sample. Samples are processed to obtain total RNA. The RNA is used as a template in a combined reverse transcription and amplification reaction to obtain fluorescent COVID-19 virus amplicons. These amplicons are hybridized on a microarray with nucleic acid probes having sequences that discriminate among the various clade variants. The microarray is imaged to detect the clade variant and each clade variant is distinguished from others by generating an intensity distribution profile from the image, which is unique to each of the clade variants.Type: ApplicationFiled: November 18, 2021Publication date: August 25, 2022Applicant: PathogenDx, Inc.Inventors: Frederick Henry Eggers, Benjamin Alan Katchman, Fushi Wen, Candy Mavis Rivas, Cory Scott Newland, Michael Edward Hogan
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Publication number: 20220251635Abstract: Provided herein is a method for detecting the presence of clade variants in the COVID-19 virus in a human sample and/or an environmental sample. Samples are processed to obtain total RNA. The RNA is used as a template in a combined reverse transcription and amplification reaction to obtain fluorescent COVID-19 virus amplicons. These amplicons are hybridized on a microarray with nucleic acid probes having sequences that discriminate among the various clade variants. The microarray is imaged to detect the clade variant. Also provided is a method of distinguishing each clade variant from others by generating an intensity distribution profile from the image, which is unique to each of the clade variants.Type: ApplicationFiled: May 27, 2021Publication date: August 11, 2022Applicant: PathogenDx, Inc.Inventors: Frederick Henry Eggers, Benjamin Alan Katchman, Fushi Wen, Candy Mavis Rivas, Cory Scott Newland, Michael Edward Hogan
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Publication number: 20220195539Abstract: Provided herein is a method for detecting the presence of a COVID-19 virus in a human sample or an environmental sample having one or more viral and bacterial pathogens. Samples processed to obtain total nucleic acids. The nucleic acids are used as a template in a reverse transcription-amplification reaction to obtain cDNA, which is used in a PCR amplification reaction to obtain fluorescent COVID-19 virus specific amplicons. These amplicons are detected by microarray hybridization near the lowest limit of detection. Also provided is a method for detecting in addition to the COVID-19 virus, the presence of respiratory disease-causing pathogens including viruses, bacteria and fungus in a single assay using the above method.Type: ApplicationFiled: November 17, 2020Publication date: June 23, 2022Applicant: PathogenDx, Inc.Inventors: Michael Edward Hogan, Benjamin Alan Katchman, Frederick Henry Eggers, Cory Scott Newland
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Publication number: 20050216765Abstract: A cryptographic device may include a cryptographic module and a communications module removably coupled thereto. The cryptographic module may include a first housing, a user network interface carried by the first housing, a cryptographic processor carried by the first housing and coupled to the user network interface, and a first connector carried by the first housing and coupled to the cryptographic processor. Furthermore, the communications module may include a second housing, a second connector carried by the second housing and being removably mateable with the first connector of the cryptographic module, and a network communications interface carried by the second housing and coupled to the second connector.Type: ApplicationFiled: March 23, 2004Publication date: September 29, 2005Applicant: Harris Corporation, Corporation of State of DelawareInventors: Eric Petkus, Bruce Yancy, Russell Dellmo, Gregory Hyland, Scott Newland, David Bolick, Lawrence Waldo, Daniel Bricher