Abstract: Embodiments provide methods and systems wherein analyte concentration readings taken over a first period of time are collected and processed to determine one or more analyte concentration averages. The methods include collecting samples with a measurement system (e.g., a Blood Glucose Meter) over a first period of time, dividing the first period of time into smaller time increments, and calculating an average analyte concentration based on first sub-averages obtained from each of the smaller time increments. Systems for carrying out the analyte concentration averages are described, as are other aspects.