Patents by Inventor Scott Pluskey

Scott Pluskey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Activated mutants of SH2-domain-containing protein tyrosine phosphatases and methods of use thereof
    Patent number: 6156551
    Abstract: The invention relates to novel mutant SH2 domain containing protein tyrosine phosphatases wherein the phosphatase is partially or constitutively active; and whose ability to regulate biological processes are different from the wildtype protein tyrosine phosphatases. The invention also relates to methods of use of the novel mutants, for example, in in vitro assays to screen for binding partners and inhibitors of protein tyrosine phosphatases and in the treatment of protein tyrosine phosphatase mediated diseases or conditions.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: December 5, 2000
    Assignees: Beth Israel Deaconess Medical Center, Joslin Diabetes Center
    Inventors: Benjamin G. Neel, Alana M. O'Reilly, Steven Shoelson, Scott Pluskey