Patents by Inventor Scott R. Johnstone

Scott R. Johnstone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR INHIBITING NEOINTIMAL FORMATION
    Publication number: 20220380408
    Abstract: Provided are peptides that based on the amino acid sequences LDPAKDCGDQKYAY (SEQ ID NO: 1) and LDPSKDCGDPKYAY (SEQ ID NO: 2), optionally wherein the peptide includes an N-terminal stearate modification. Also provided are method for using the disclosed peptides for inhibiting neointima formation in mammals, methods for inhibiting division and/or proliferation of vascular smooth muscle cells, and uses of the disclosed peptides for treating cardiovascular diseases and/or disorder associated with undesirable vascular SMC proliferation, which in some embodiments can re-late to inhibiting neointima formation in a mammal.
    Type: Application
    Filed: July 27, 2020
    Publication date: December 1, 2022
    Applicant: University of Virginia Patent Foundation
    Inventors: Scott R. Johnstone, Brant E. Isakson