Patents by Inventor Scott R. Manales

Scott R. Manales has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting chemical interactions between naturally occurring biological analyte molecules that are non-identical binding partners
    Patent number: 6436647
    Abstract: A method of using micromechanical devices as sensors for detecting chemical interactions between naturally occurring bio-polymers which are non-identical binding partners is provided. The method is useful whether the reactions occur through electrostatic forces or other forces. Induced stress, heat, or change in mass is detected where a binding partner is placed on a cantilever for possible reaction with an analyte molecules (i.e., a non-identical binding partner). The method is particularly useful in determining DNA hybridization but may be useful in detecting interaction in any chemical assay.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: August 20, 2002
    Assignee: Affymetrix, Inc.
    Inventors: Calvin F. Quate, Mark O. Trulson, Scott R. Manales, Jonathan E. Forman
  • Method for detecting chemical interactions between naturally occurring bio-polymers which are non-identical binding partners
    Patent number: 6203983
    Abstract: A method of using micromechanical devices as sensors for detecting chemical interactions between naturally occurring bio-polymers which are non-identical binding partners is provided. The method is useful whether the reactions occur through electrostatic forces or other forces. Induced stress, heat, or change in mass is detected where a binding partner is placed on a cantilever for possible reaction with an analyte molecules (i.e., a non-identical binding partner). The method is particularly useful in determining DNA hybridization but may be useful in detecting interaction in any chemical assay.
    Type: Grant
    Filed: June 16, 1998
    Date of Patent: March 20, 2001
    Assignee: Affymetrix, Inc.
    Inventors: Calvin F. Quate, Mark O. Trulson, Scott R. Manales, Jonathan E. Forman