Abstract: A device configured to receive and insulate a blood bag. The device includes a first side wall and a second side wall coupled to the first side wall and forms a cavity configured to receive the blood bag. The device is in contact with the blood bag over a majority of the surface area of the blood bag. The device also includes a plurality of individual pockets filled with air having a pocket density (e.g., the number of pockets per square centimeter) in a range of about 0.005-50 pockets per square centimeter. The device also includes a defined area absent the pockets with the defined area configured to cover at least a portion of a label on the blood bag such that the label remains human readable.