Abstract: In some embodiments, the disclosure relates generally to compositions, comprising a single reaction mixture containing a plurality of different populations of discrete supports, and a plurality of different populations of target nucleic acids. The single reaction mixture can contain a first population of beads; a second population of beads; a first population of target nucleic acids, where at least two different target nucleic acids in the first population of target nucleic acids can bind to a bead in the first population of beads; and a second population of target nucleic acids, where at least two different target nucleic acids in the second population of target nucleic acids can bind to a bead in the second population of beads. The single reaction mixture can be employed to monoclonally amplify the first target nucleic acids on the first beads, and monoclonally amplify the second target nucleic acids on the second beads.

Abstract: Disclosed in an orthopedic implant that comprises a spacer portion having a superior portion and an inferior portion, and a staple portion. The staple portion is integral with the spacer portion and comprises a crown portion and first and second leg portions, the first and second leg portions having distal end that converge from the crown portion and that are composed of a material that has superelastic properties at body temperatures, whereby the first and second leg portions are configured to impart a compressive biasing force when the implant is installed with the legs under tension.

Abstract: A rod belt, in particular for rod belt conveyors of agricultural machines, the rod belt having a running direction and comprising: tensile stress-resistant, elastic and continuous belts running in parallel to one another; transverse rods arranged perpendicular to the running direction and parallel to one another in a pre-determined rod spacing, each transverse rod having mounting sections with which the transverse rods rests on the belts, wherein the transverse rods are fastened to the belts by attachment means, passing through the mounting sections of the transverse rods and the belts; and protective forge covers attached to the belts, each forge cover having a mounting profile and a flexible protection profile.

Abstract: A surgical fastener applying device for releasable connection to an end effector is provided. The surgical fastener applying device includes an elongated body portion having an outer tube and an inner shaft assembly. The inner shaft assembly defines a non-circular bore in a distal end thereof. The inner shaft assembly is longitudinally movable through the outer tube. The outer tube and the inner shaft assembly define corresponding openings extending radially therethrough. The surgical fastener applying device includes a detent movable within the openings of the elongated body portion. The detent floats between the end effector and the elongated body portion to enable selective connection between the end effector and the elongated body portion.

Abstract: A removable light for a towed vehicle includes a housing with a low profile shape, an anchor, a safety tether strap, and lens protection features.

Abstract: A joint connects a first portion of a tool to a second portion of the tool. The joint comprises a first elongated portion, a second elongated portion, and a hub. The first elongated portion is configured to couple to the first portion of the tool and includes a first joint end. The second elongated portion is configured to couple to the second portion of the tool and includes a second joint end with a plurality of cavities formed therein. The hub is positioned between the first joint end and the second joint end and is shiftable between a locked position and an unlocked position. The hub includes a projection that is operable to extend into one of the cavities when in the locked position and shift out of the cavities when in the unlocked position.

Abstract: A removable light for a towed vehicle includes a housing with a low profile shape, an anchor, a safety tether strap, and lens protection features.

Abstract: A joint connects a first portion of a tool to a second portion of the tool. The joint comprises a first elongated portion, a second elongated portion, and a hub. The first elongated portion is configured to couple to the first portion of the tool and includes a first joint end. The second elongated portion is configured to couple to the second portion of the tool and includes a second joint end with a plurality of cavities formed therein. The hub is positioned between the first joint end and the second joint end and is shiftable between a locked position and an unlocked position. The hub includes a projection that is operable to extend into one of the cavities when in the locked position and shift out of the cavities when in the unlocked position.

Abstract: A connector assembly for providing electrical connection from an electrical device ground wire to a vehicle chassis ground comprises a wire connector, a cable, and a surface connector. The wire connector is configured to receive the electrical device ground wire. The cable is electrically connected to the ground wire. The surface connector is coupled to the cable and configured to attach to a vehicle chassis. The surface connector includes a conductive disc, an outer insulating ring, and an inner insulating ring. The conductive disc is electrically connected to the cable and includes a central opening configured to receive a fastener which attaches the surface connector to the chassis. The inner insulating ring, a portion of the lower surface of the conductive disc, and the outer insulating ring form a hermetically sealed chamber with the chassis when the surface connector is attached to the chassis.

Abstract: Chainsaws are provided. A chainsaw includes a housing, a motor, a bar fixedly coupled to the housing and configured to form a cutting track, a cutting implement configured to move along the cutting track and drivable by the motor, and a tensioning system configured to adjust tension in the cutting implement.

Abstract: A connector assembly for providing electrical connection from an electrical device ground wire to a vehicle chassis ground comprises a wire connector, a cable, and a surface connector. The wire connector is configured to receive the electrical device ground wire. The cable is electrically connected to the ground wire. The surface connector is coupled to the cable and configured to attach to a vehicle chassis. The surface connector includes a conductive disc, an outer insulating ring, and an inner insulating ring. The conductive disc is electrically connected to the cable and includes a central opening configured to receive a fastener which attaches the surface connector to the chassis. The inner insulating ring, a portion of the lower surface of the conductive disc, and the outer insulating ring form a hermetically sealed chamber with the chassis when the surface connector is attached to the chassis.

Abstract: A surgical fastener applying device for releasable connection to an end effector is provided. The surgical fastener applying device includes an elongated body portion having an outer tube and an inner shaft assembly. The inner shaft assembly defines a non-circular bore in a distal end thereof. The inner shaft assembly is longitudinally movable through the outer tube. The outer tube and the inner shaft assembly define corresponding openings extending radially therethrough. The surgical fastener applying device includes a detent movable within the openings of the elongated body portion. The detent floats between the end effector and the elongated body portion to enable selective connection between the end effector and the elongated body portion.

Abstract: A surgical fastener applying device for releasable connection to an end effector is provided. The surgical fastener applying device includes an elongated body portion having an outer tube and an inner shaft assembly. The inner shaft assembly defines a non-circular bore in a distal end thereof. The inner shaft assembly is longitudinally movable through the outer tube. The outer tube and the inner shaft assembly define corresponding openings extending radially therethrough. The surgical fastener applying device includes a detent movable within the openings of the elongated body portion. The detent floats between the end effector and the elongated body portion to enable selective connection between the end effector and the elongated body portion.

Abstract: The present invention relates to a construct including a porous core, a cargo, and a spacer disposed between the core and the cargo. In some examples, the construct further includes an outer layer composed of a lipid, a polymer, or a combination thereof. Methods of making and employing such constructs are also described herein.

Abstract: Systems, tools, and screws for reducing a bone fracture are disclosed. In embodiments, the system comprises: a screw, a driver, a sleeve comprising a longitudinal bore configured to enable insertion of the driver through the sleeve, a locking mechanism configurable into a first state that locks the sleeve to the driver and a second state that unlocks the sleeve from the driver, and a retaining sleeve coupled to a first end of the driver and configured to couple to the screw. In the first state, the sleeve applies a compressive force while distal threads of the screw are driven into the bone while retaining proximal threads of the screw in the sleeve. After a desired compression is achieved, the locking mechanism is configured to the second state, allowing the proximal threads of the screw to be driven into the bone while maintaining application of the compressive force to the bone.

Abstract: A deployment device and an associated surgical fastener as well as their methods of use are disclosed. In one embodiment, the deployment device includes a restraining mechanism constructed and arranged to temporarily limiting movement of a surgical fastener back span. The surgical fastener includes two legs extending in a distal direction from opposing ends of the back span. The legs are in a first closed position with a first shape. The deployment device also includes a spreader configured and arranged to engage the legs of the surgical fastener in the first closed position. When the spreader is moved in a distal direction relative to the back span, the spreader spreads the legs of the surgical fastener from the first closed position to a second open position as the back span is limited from distally moving by the restraining mechanism.

Abstract: Systems, tools, and screws for reducing a bone fracture are disclosed. In embodiments, the system comprises: a screw, a driver, a sleeve comprising a longitudinal bore configured to enable insertion of the driver through the sleeve, a locking mechanism configurable into a first state that locks the sleeve to the driver and a second state that unlocks the sleeve from the driver, and a retaining sleeve coupled to a first end of the driver and configured to couple to the screw. In the first state, the sleeve applies a compressive force while distal threads of the screw are driven into the bone while retaining proximal threads of the screw in the sleeve. After a desired compression is achieved, the locking mechanism is configured to the second state, allowing the proximal threads of the screw to be driven into the bone while maintaining application of the compressive force to the bone.

Abstract: A method of determining 3D coordinates of a reference point comprises positioning a targeting device comprising an elongated rigid rod having an end point and first and second scanning targets affixed to the rod, the targeting device positioned such that the end point contacts the reference point; scanning the targeting device; determining, using the scan data, (i) 3D coordinates of the center point of the first target and (ii) 3D coordinates of the center point of the second target; and calculating 3D coordinates of the end point based on (i) the 3D coordinates of the center point of the first target, (ii) the 3D coordinates of the center point of the second target, (iii) a distance between the center point of the first target and the end point, and (iv) a distance between the center point of the second target and the end point.

Abstract: A deployment device and an associated surgical fastener as well as their methods of use are disclosed. In one embodiment, the deployment device includes a restraining mechanism constructed and arranged to temporarily limiting movement of a surgical fastener back span. The surgical fastener includes two legs extending in a distal direction from opposing ends of the back span. The legs are in a first closed position with a first shape. The deployment device also includes a spreader configured and arranged to engage the legs of the surgical fastener in the first closed position. When the spreader is moved in a distal direction relative to the back span, the spreader spreads the legs of the surgical fastener from the first closed position to a second open position as the back span is limited from distally moving by the restraining mechanism.

Abstract: A deployment device and an associated surgical fastener as well as their methods of use are disclosed. In one embodiment, the deployment device includes a restraining mechanism constructed and arranged to temporarily limiting movement of a surgical fastener back span. The surgical fastener includes two legs extending in a distal direction from opposing ends of the back span. The legs are in a first closed position with a first shape. The deployment device also includes a spreader configured and arranged to engage the legs of the surgical fastener in the first closed position. When the spreader is moved in a distal direction relative to the back span, the spreader spreads the legs of the surgical fastener from the first closed position to a second open position as the back span is limited from distally moving by the restraining mechanism.