Abstract: A lay flat handle for a dog restraint includes an elastic strap and a handle strap. The elastic strap normally urges the handle strap into a lay flat position. A first end of the handle strap can be positioned under a first end of the elastic strap and a second end of the handle strap can be positioned under a second end of the elastic strap. The dog restraint can be a collar, a harness, or a leash. The lay flat handle can also be used in other applications.

Abstract: Disclosed are methods by which compounds/molecules capable of binding antigens, for example antibody type compounds/molecules, can be purified, extracted and/or selected. The methods may be used to purify, extract or select a specific type (or types) of binding agent from a mixed composition. The methods may be used to extract or purify specific binding agents from mixed compositions, which compositions comprise other agents capable of binding other antigens. The methods may find particular application as methods for the purification of blood group antigen antibodies.

Abstract: The present invention is based on the finding that red blood cell antigens can be exploited as a means to detect red blood cells/erythrocytes. Specifically, by identifying red blood cell antigens which are expressed by substantially all red blood cell types, it is possible to provide a method which achieves the reliable detection of red blood cells.

Abstract: The present invention provides novel methods for the detection of antibodies, in particular, blood group antibodies. The methods of this invention may be applied to pre-transfusion blood compatibility testing for the detection of incompatibility between donor units (comprising donor red blood cells (erythrocytes)) and a recipient.

Abstract: Disclosed are methods by which compounds/molecules capable of binding antigens, for example antibody type compounds/molecules, can be purified, extracted and/or selected. The methods may be used to purify, extract or select a specific type (or types) of binding agent from a mixed composition. The methods may be used to extract or purify specific binding agents from mixed compositions, which compositions comprise other agents capable of binding other antigens. The methods may find particular application as methods for the purification of blood group antigen antibodies.

Abstract: The present invention provides novel methods for the detection of antibodies, in particular, blood group antibodies. The methods of this invention may be applied to pre-transfusion blood compatibility testing for the detection of incompatibility between donor units (comprising donor red blood cells (erythrocytes)) and a recipient.

Abstract: The present invention is based on the finding that red blood cell antigens can be exploited as a means to detect red blood cells/erythrocytes. Specifically, by identifying red blood cell antigens which are expressed by substantially all red blood cell types, it is possible to provide a method which achieves the reliable detection of red blood cells.

Abstract: The present invention relates to methods of detecting specific cell surface antigens present in a sample of cells being tested and in particular blood group antigens, which methods do not employ the addition of extrinsic labels to detect said cell surface antigens. Typically detection is carried out using an intrinsic fluorescence capability of the cells being tested.

Abstract: An assay for the detection of antibodies to blood group antigens is provide and includes a solid substrate having immobilised thereon a fragment of cell membrane which presents a blood group antigen capable of binding to a blood group antibody. The cell fragments are preferably from red blood cells. The antigens may be immobilised in the form of an array of spots.

Abstract: The present invention relates to methods of detecting specific cell surface antigens present in a sample of cells being tested and in particular blood group antigens, which methods do not employ the addition of extrinsic labels to detect said cell surface antigens. Typically detection is carried out using an intrinsic fluorescence capability of the cells being tested.

Abstract: A valve assembly is provided including at least one pneumatic component and a pneumatic tube assembly fixedly coupled to the at least one pneumatic component. The pneumatic tube assembly includes a pneumatic tube and at least one tube retaining plate. The at least one tube retaining is fixedly coupled about the pneumatic tube by a weld or brazing process. The at least one tube retaining plate further includes a portion positioned in bonding engagement with a bonding surface of the at least one pneumatic component. A retaining bolt mechanically retains the at least one tube retaining plate to the bonding surface. The retaining bolt and the at least one tube retaining plate provide a bonding path between the pneumatic tube and the at least one pneumatic component.

Abstract: An apparatus is provided for a regulator valve comprising a duct, a valve element, a regulator unit, and a fluid pressure sensor. The duct has an inner surface that defines a flow passage. The valve element is movably disposed within the duct flow passage. The regulator unit is coupled to the valve element, and is further coupled to receive fluid at a feedback pressure magnitude. The regulator unit is configured to controllably position the valve element based at least in part on the feedback pressure magnitude, to thereby regulate fluid pressure downstream of the valve element to a regulated pressure magnitude that results in a static pressure magnitude at least proximate the duct inner surface. The fluid pressure sensor is disposed downstream of the valve element, and is configured to supply the fluid at the feedback pressure magnitude, with the feedback pressure magnitude being less than the static pressure magnitude.