Abstract: Methods of respiration compensation including detecting a position of a catheter proximate a target within a patient, performing a local registration to update a displayed relative position and orientation of the catheter and the target in a three-dimensional model, detecting movement of a plurality of sensors, determining a respiration waveform from the detected movement of the plurality of sensors, and indicating on a user-interface a period during which advancement of a biopsy or therapy tool from the catheter is most likely to intersect the target, wherein the period corresponds to a portion of the respiration waveform during which the movement of the plurality of sensors is within a desired range.

Abstract: A system and method for luminal navigation of a catheter including a sensor and a computing device. The computing device executing steps of receiving magnetic resonance signals from a magnetic resonance image (MRI) scanner and to generate an MRI image data set, generating a three-dimensional (3D) model from the MRI image data set, generating a pathway through the 3D model to a target, determining a location of the sensor within the patient, displaying a location of a portion of the catheter in the 3D model, updating the displayed location of the portion of the catheter, receiving second magnetic resonance signals and generate a second MRI image data set, receiving an indication of a distal end of the catheter in the second MRI image data set, and updating a relative position of a distal end of the catheter and the target in the 3D model.

Abstract: Methods of respiration compensation including detecting a position of a catheter proximate a target within a patient, performing a local registration to update a displayed relative position and orientation of the catheter and the target in a three-dimensional model, detecting movement of a plurality of sensors, determining a respiration waveform from the detected movement of the plurality of sensors, and indicating on a user-interface a period during which advancement of a biopsy or therapy tool from the catheter is most likely to intersect the target, wherein the period corresponds to a portion of the respiration waveform during which the movement of the plurality of sensors is within a desired range.

Abstract: A method of monitoring a physiologic condition includes suspending, via trans-tracheal implantation, a dual pressure sensor for exposure to a bidirectional airflow within the trachea. A respiratory parameter is measured via the dual pressure sensor based on an airflow-induced pressure differential sensed by the dual pressure sensor, and a physiologic condition is determined via the measured respiratory parameter.

Abstract: A method of monitoring a physiologic condition includes suspending, via trans-tracheal implantation, a dual pressure sensor for exposure to a bidirectional airflow within the trachea. A respiratory parameter is measured via the dual pressure sensor based on an airflow-induced pressure differential sensed by the dual pressure sensor, and a physiologic condition is determined via the measured respiratory parameter.