Abstract: The disclosure concerns a method of treating a disorder characterised by chondrocyte hypertrophy e.g. osteoarthritis, and a composition for use in such a method. The disclosure also concerns a method of producing a miniaturised model of endochondral ossification, and a miniaturised model of endochondral ossification producible by such method. The disclosure further provides a method of screening for compositions for use in treating a disorder characterised by chondrocyte hypertrophy, and a composition identified by such method.

Abstract: A winglet for attachment to a wing portion of an aircraft is disclosed having a winglet tip and a winglet root opposite from the winglet tip. The winglet has an opening for receiving therethrough a connector for connecting the winglet to a wing portion in use. The winglet has a retainer internal of the winglet for use in retaining the connector relative to the winglet. The retainer has a hole that extends along an axis that passes through the opening for receiving therethrough a portion of the connector when the connector is located through the opening. The retainer includes a body for reacting against a retention component with which the connector engages in use.

Abstract: A winglet for attachment to a wing portion of an aircraft is disclosed having a winglet tip and a winglet root opposite from the winglet tip. The winglet has an opening for receiving therethrough a connector for connecting the winglet to a wing portion in use. The winglet has a retainer internal of the winglet for use in retaining the connector relative to the winglet. The retainer has a hole that extends along an axis that passes through the opening for receiving therethrough a portion of the connector when the connector is located through the opening. The retainer includes a body for reacting against a retention component with which the connector engages in use.

Abstract: An illuminated safety vest assembly includes a vest that is worn on a user. A plurality of reflecting strips is each coupled to the vest. Each of the reflecting strips is comprised of a light reflecting material to reflect light thereby enhancing visibility of the user when the user wears the vest in a darkened environment. A plurality of light emitters is each of the light emitter is integrated into the vest. The light emitters emit light outwardly from the vest when the light emitters are turned on thereby enhancing visibility of the user. A switch is slidably coupled to the vest and the switch is electrically coupled to each of the plurality of light emitters for turning the plurality of light emitters on and off. A plurality of conductors is each electrically coupled between the switch and a respective one of the plurality of light emitters.

Abstract: Systems and methods for operating a Point Of Sale (“POS”) system. The methods comprise: performing operations by the POS system to machine learn at least information about a condition of an article to be purchased using at least one of imaging, sensing, and short range communications; determining by the POS system if the article is accepted for purchase based at least on the machine learned information about the condition of the article; and completing a purchase transaction by the POS system if a determination is made that the article is accepted for purchase. The POS system may also perform operations to deactivate a security tag coupled to the article or actuate a detachment mechanism of the security tag, if the article was successfully purchased during the purchase transaction.

Abstract: A winglet for attachment to a wing portion of an aircraft comprises a winglet tip and a winglet root opposite from the winglet tip. The winglet has an opening for receiving therethrough a connector for connecting the winglet to a wing portion in use. The winglet has a retainer internal of the winglet for use in retaining the connector relative to the winglet. The retainer has a hole that extends along an axis that passes through the opening for receiving therethrough a portion of the connector when the connector is located through the opening. The retainer comprising a body for reacting against a retention component with which the connector engages in use.

Abstract: Systems and methods for operating a Point Of Sale (“POS”) system. The methods comprise: performing operations by the POS system to machine learn at least information about a condition of an article to be purchased using at least one of imaging, sensing, and short range communications; determining by the POS system if the article is accepted for purchase based at least on the machine learned information about the condition of the article; and completing a purchase transaction by the POS system if a determination is made that the article is accepted for purchase. The POS system may also perform operations to deactivate a security tag coupled to the article or actuate a detachment mechanism of the security tag, if the article was successfully purchased during the purchase transaction.

Abstract: A winglet for attachment to a wing portion of an aircraft is disclosed having a winglet tip and a winglet root opposite from the winglet tip. The winglet has an opening for receiving therethrough a connector for connecting the winglet to a wing portion in use. The winglet has a retainer internal of the winglet for use in retaining the connector relative to the winglet. The retainer has a hole that extends along an axis that passes through the opening for receiving therethrough a portion of the connector when the connector is located through the opening. The retainer includes a body for reacting against a retention component with which the connector engages in use.

Abstract: A winglet for attachment to a wing portion of an aircraft is disclosed having a winglet tip and a winglet root opposite from the winglet tip. The winglet has an opening for receiving therethrough a connector for connecting the winglet to a wing portion in use. The winglet has a retainer internal of the winglet for use in retaining the connector relative to the winglet. The retainer has a hole that extends along an axis that passes through the opening for receiving therethrough a portion of the connector when the connector is located through the opening. The retainer includes a body for reacting against a retention component with which the connector engages in use.

Abstract: Processes for recovering paraxylene from at least two feedstreams containing xylene isomers. The process includes directing to a paraxylene recovery zone comprising at least one crystallization zone, a paraxylene-lean feedstream having a paraxylene to total xylene isomer ratio of 0.50 or less, and also directing to the paraxylene recovery zone, a paraxylene-rich feedstream having a paraxylene to total xylene isomer ratio of greater than 0.50. A paraxylene-containing product stream is recovered from the paraxylene recovery zone having a paraxylene to total xylene isomer ratio greater than that of the paraxylene-rich feedstream. The process provides improvements in paraxylene recovery efficiency and/or cost effectiveness.

Abstract: A winglet for attachment to a wing portion of an aircraft comprises a winglet tip and a winglet root opposite from the winglet tip. The winglet has an opening for receiving therethrough a connector for connecting the winglet to a wing portion in use. The winglet has a retainer internal of the winglet for use in retaining the connector relative to the winglet. The retainer has a hole that extends along an axis that passes through the opening for receiving therethrough a portion of the connector when the connector is located through the opening. The retainer comprising a body for reacting against a retention component with which the connector engages in use.

Abstract: Visual landmarks are used to organize diagrams. Elements of a diagram can be arranged in accordance with configurable defined properties of visual landmarks to provide some degree of layout structure within the diagram. Users can customize visual landmarks to cause the visual landmarks to exhibit desired behavior.

Abstract: Wafer carrier washing and drying apparatus and method, especially useful for the semiconducting industry.

Abstract: The present invention relates to methods and compositions for osteogenic differentiation of human periosteum derived cells, in particular using a growth medium containing a specific combination of growth factors and formulations thereof. The invention also relates to the differentiated cells and cell populations, as well as further products comprising such cells and uses thereof in bone therapy.

Abstract: Visual landmarks are used to organize diagrams. Elements of a diagram can be arranged in accordance with configurable defined properties of visual landmarks to provide some degree of layout structure within the diagram. Users can customize visual landmarks to cause the visual landmarks to exhibit desired behavior.

Abstract: The present invention extends to methods, systems, and computer program products for using visual landmarks to organize diagrams. Embodiments of the invention facilitate using visual landmarks to organize elements within a diagram. Elements of a diagram can be arranged in accordance with configurable defined properties of visual landmarks to provide some degree of layout structure within the diagram. Accordingly, embodiments of the invention provide a user experience that provides some structure but retains the flexibility of free form editing. Users can customize visual landmarks to cause the visual landmarks to exhibit desired behavior.

Abstract: An apparatus and method of uniformly heating, rheologically softening, and thermoplastically forming metallic glasses rapidly into a net shape using a rapid capacitor discharge forming (RCDF) tool in combination with an electromagnetic force generated by the interaction of the applied current with a transverse magnetic field. The RCDF method utilizes the discharge of electrical energy stored in a capacitor to uniformly and rapidly heat a sample or charge of metallic glass alloy to a predetermined “process temperature” between the glass transition temperature of the amorphous metal and the equilibrium melting point of the alloy in a time scale of several milliseconds or less, at which point the interaction between the electric field and the magnetic field generates a force capable of shaping the heated sample into a high quality amorphous bulk article via any number of techniques including, for example, injection molding, dynamic forging, stamp forging, and blow molding in a time scale of less than one second.

Abstract: Disclosed is a physical therapy support, comprising a planar structure having a first and second end and an upper and lower surface that reduces friction between the lower body of a patient and a hospital bed. The device is positioned between a patient's hips and the underlying bed sheets, whereby the patient is elevated and separated from the sheets to allow freedom of movement and increased support when engaging in hip and lower body movements for recovery and physical therapy sessions. The shape of the device includes a first rounded end and a second flat end to form a triangular shape having tapering longitudinal sides. The cross section comprises a thin, rigid and uniform material having a low friction upper surface and a high friction lower surface. A slot penetration along the one of the tapering sides allows for handling of the device and for transporting between patients.

Abstract: An apparatus and method of uniformly heating, rheologically softening, and thermoplastically forming metallic glasses rapidly into a net shape using a rapid capacitor discharge forming (RCDF) tool in combination with an electromagnetic force generated by the interaction of the applied current with a transverse magnetic field. The RCDF method utilizes the discharge of electrical energy stored in a capacitor to uniformly and rapidly heat a sample or charge of metallic glass alloy to a predetermined “process temperature” between the glass transition temperature of the amorphous metal and the equilibrium melting point of the alloy in a time scale of several milliseconds or less, at which point the interaction between the electric field and the magnetic field generates a force capable of shaping the heated sample into a high quality amorphous bulk article via any number of techniques including, for example, injection molding, dynamic forging, stamp forging, and blow molding in a time scale of less than one second.