Abstract: Disclosed herein are products, methods, and uses for treating, ameliorating, delaying the progression of, and/or preventing a muscular dystrophy or a cancer including, but not limited to, facioscapulohumeral muscular dystrophy (FSHD) or a cancer associated with DUX4 expression or overexpression. More particularly, disclosed herein are RNA interference-based products, methods, and uses for inhibiting or downregulating the expression of double homeobox 4 (DUX4). Even more particularly, the disclosure provides microRNA (miRNA) for inhibiting or downregulating the expression of DUX4 and methods of using said miRNA to inhibit or downregulate DUX4 expression in cells and/or in cells of a subject having a muscular dystrophy or a cancer including, but not limited to, FSHD or a cancer associated with DUX4 expression or overexpression.

Abstract: Methods and associated systems that allow a plurality of real-time multimedia applications to operate concurrently within a computer system with constrained primary memory. In particular, the methods and systems of the present invention allow for a plurality of real-time multimedia applications to operate concurrently while adapting to changing memory constraints imposed by the dynamic allocation and release of primary memory in a shared primary memory space.

Abstract: Methods and associated systems that allow a plurality of real-time multimedia applications to operate concurrently within a computer system with constrained primary memory. In particular, the methods and systems of the present invention allow for a plurality of real-time multimedia applications to operate concurrently while adapting to changing memory constraints imposed by the dynamic allocation and release of primary memory in a shared primary memory space.