Abstract: A method and system estimate the risk of malignancy of a given region of interest using noninvasive MRI techniques. The determination of risk is based on the morphology and kinetic enhancement of a region of interest. In addition, the method and system use the type of the enhancement curve to determine the level of risk associated with a given region of interest. The region of interest can be a lesion, tumor, or other unknown. The imaging can be done with the aid of a contrast agent. Regions meeting component concentration criteria, time-change dynamic criteria and the like are distinctly colored and displayed on a single image. Different colors can be shown locally to identify predetermined levels of risk, and/or associated with predetermined compositions such as contrast agents, or to show the presence of silicone.

Abstract: An MRI process and system image a volume of a sample in a magnetic field established by a biasing field magnet and an array of gradient magnet fields using a pulse sequence to obtain a response that is decoded into an image or images. A set of successive images is collected while the contrast associated with lesions and tumors is enhanced with a contrast agent. A non-spoiled reference image is acquired before the application of the contrast agent. The reference image is non-spoiled in that the pulse sequence for collecting a portion of the volume image is not randomized in phase in a manner that would reset the phase effects of a previous pulse sequence. At least one other one of the successive images collected using phase spoiling pulse sequences. The non-spoiled image data is registered with and subtracted from the successive images to enhance the appearance of selected compositions in the output image, such as the contrast agent and/or water to highlight lesions and cysts, or silicone from an implant, etc.