Patents by Inventor Scott Throner

Scott Throner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PURINE DERIVATIVES AS ANTICANCER AGENTS
    Publication number: 20240059689
    Abstract: Compounds are provided according to Formula (I) and pharmaceutically acceptable salts, hydrates, solvates, prodrugs, tautomers and stereoisomers, as well as pharmaceutical compositions, wherein Ring B, Ring A, RA, Rb, Rc, Rc?, R1, R2, R6, m and n are as defined herein. The compounds disclosed herein are contemplated to be useful for the prevention and treatment of a variety of conditions.
    Type: Application
    Filed: September 15, 2023
    Publication date: February 22, 2024
    Inventors: Scott Throner, Daniel Jönsson
  • CYCLOPROPYL AMIDE DERIVATIVES
    Publication number: 20150216861
    Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Application
    Filed: April 13, 2015
    Publication date: August 6, 2015
    Inventors: James Arnold, Andrew Todd Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
  • Cyclopropyl amide derivatives
    Patent number: 9029381
    Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: May 12, 2015
    Assignee: Astrazeneca AB
    Inventors: James Arnold, Todd Andrew Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
  • Metabotropic glutamate receptor isoxazole ligands and their use as potentiators—286
    Patent number: 8148372
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: April 3, 2012
    Assignee: AstraZeneca AB
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M Hunter, Scott Throner
  • Cyclopropyl Amide Derivatives '978
    Publication number: 20120065193
    Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Application
    Filed: November 21, 2011
    Publication date: March 15, 2012
    Inventors: James Arnold, Andrew Todd Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
  • Cyclopropyl amide derivatives
    Patent number: 8063215
    Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Grant
    Filed: August 21, 2008
    Date of Patent: November 22, 2011
    Assignee: AstraZeneca AB
    Inventors: James Arnold, Todd Andrew Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
  • Metabotropic glutamate receptor isoxazole ligands and their use as potentiators
    Patent number: 7888353
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: February 15, 2011
    Assignee: AstraZeneca AB
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M Hunter, Scott Throner
  • METABOTROPIC GLUTAMATE RECEPTOR ISOXAZOLE LIGANDS AND THEIR USE AS POTENTIATORS
    Publication number: 20100324044
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: August 26, 2010
    Publication date: December 23, 2010
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M Hunter, Scott Throner
  • Metabotropic Glutamate Receptor Isoxazole Ligands and Their Use as Potentiators - 286
    Publication number: 20100317662
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: August 20, 2010
    Publication date: December 16, 2010
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M. Hunter, Scott Throner
  • Metabotropic glutamate receptor isoxazole ligands and their use as potentiators 286
    Patent number: 7790760
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: September 7, 2010
    Assignee: AstraZeneca AB
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M. Hunter, Scott Throner
  • Metabotropic glutamate receptor isoxazole ligands and their use as potentiators—286
    Patent number: 7781434
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: August 24, 2010
    Assignee: AstraZeneca AB
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M Hunter, Scott Throner
  • Metabotropic Glutamate Receptor Isoxazole Ligands and Their Use as Potentiators - 286
    Publication number: 20100022545
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: October 8, 2009
    Publication date: January 28, 2010
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M. Hunter, Scott Throner
  • Metabotropic Glutamate Receptor Isoxazole Ligands and Their Use as Potentiators 286
    Publication number: 20090306158
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: June 3, 2009
    Publication date: December 10, 2009
    Applicant: AstraZeneca AB
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M. Hunter, Scott Throner
  • Substituted Amino-Compounds and Uses Thereof
    Publication number: 20090221579
    Abstract: This invention relates to novel compounds having the structural formula Ia or formula Ib: Ia Ib and their pharmaceutically acceptable salts, tautomers or in vivo hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of A? related pathologies such as cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.
    Type: Application
    Filed: October 14, 2005
    Publication date: September 3, 2009
    Inventors: Jeffrey Scott Albert, Don Andisik, James Arnold, Dean Brown, Owen Callaghan, James Campbell, Robin Arthur Ellis Carr, Gianni Chessari, Miles Stuart Congreve, Phil Edwards, James R. Empfield, Martyn Frederickson, Gerard M. Koether, Jennifer Krumrine, Russ Mauger, Christopher William Murray, Sahil Patel, Mark Sylvester, Scott Throner
  • Cyclopropyl Amide Derivatives 978
    Publication number: 20090076020
    Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Application
    Filed: August 21, 2008
    Publication date: March 19, 2009
    Applicant: ASTRAZENECA AB
    Inventors: James Arnold, Todd Andrew Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
  • Substituted Amino-Pyrimidones and Uses Thereof
    Publication number: 20090062282
    Abstract: This invention relates to novel compounds having the structural formula Ia or formula Ib below: (Ia, Ib), and their pharmaceutically acceptable salts, tautomers or in vivo hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of A? related pathologies such as cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.
    Type: Application
    Filed: October 14, 2005
    Publication date: March 5, 2009
    Applicant: AstraZeneca AB
    Inventors: Jeffrey Scott Albert, Don Andisik, James Arnold, Dean Brown, Owen Callaghan, James Campbell, Robin Arthur Ellis Carr, Gianni Chessari, Miles Stuart Congreve, Phil Edwards, James R. Empfield, Martyn Frederickson, Gerard M. Koether, Jennifer Krumrine, Russ Mauger, Christopher William Murray, Sahil Patel, Mark Sylvester, Scott Throner
  • 5-Substituted Imidazoles
    Publication number: 20080188518
    Abstract: Compounds of formula I: wherein A and R1 are as defined in the specification, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially in the treatment or prophylaxis of psychotic and intellectual impairment disorders.
    Type: Application
    Filed: November 15, 2004
    Publication date: August 7, 2008
    Applicant: ASTRA ZENECA AB
    Inventors: James Empfield, Eifion Phillips, Scott Throner
  • 4-substituted imidazoles
    Patent number: 7384954
    Abstract: Compounds of formula I: wherein A and R1 are as defined in the specification, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially in the treatment or prophylaxis of psychotic and intellectual impairment disorders.
    Type: Grant
    Filed: November 15, 2004
    Date of Patent: June 10, 2008
    Assignee: AstraZeneca AB
    Inventors: James R. Empfield, Eifion Phillips, Scott Throner
  • 4-Substituted imidazoles
    Publication number: 20070105896
    Abstract: Compounds of formula I: wherein A and R1 are as defined in the specification, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially in the treatment or prophylaxis of psychotic and intellectual impairment disorders.
    Type: Application
    Filed: November 15, 2004
    Publication date: May 10, 2007
    Applicant: AstraZeneca AB
    Inventors: James Empfield, Eifion Phillips, Scott Throner