Abstract: A system for infrared analysis of a target surface region of a subject includes a reservoir containing a medium at a predetermined temperature and a conduit defining a channel for transmitting the medium from the reservoir to the target surface region. The conduit may have a first end that is attached to an outlet of the reservoir and a second end that is flexibly conformable to a shape corresponding to a perimeter of the target surface region. The system may further include an infrared camera(s) operable to capture infrared image data of the target surface region and one or more processors operable to produce a representation of the captured infrared image data at a plurality of timings relative to the transmission of the medium from the reservoir to the target surface region. Adjunctive reflective surfaces may ensure that IR signals from target geometric surfaces can be captured for analysis.

Abstract: Methods and applicator apparatus are disclosed for brachytherapy treatment of tissue surrounding a cavity in a patient, particularly a resection cavity. In treatment regimes requiring recovery time between successive radiation treatments, applicators of the invention are retained under the skin, with the skin allowed to at least partially heal, and are re-accessed later for one or more subsequent treatments. To reduce patient discomfort an anesthetic agent can be infused through the applicator to patient tissue, for insertion, balloon inflation or removal of the applicator.

Abstract: Methods and applicator apparatus are disclosed for brachytherapy treatment of tissue surrounding a cavity in a patient, particularly a resection cavity. In treatment regimes requiring recovery time between successive radiation treatments, applicators of the invention are retained under the skin, with the skin allowed to at least partially heal, and are re-accessed later for one or more subsequent treatments. To reduce patient discomfort an anesthetic agent can be infused through the applicator to patient tissue, for insertion, balloon inflation or removal of the applicator.