Patents by Inventor Scott Tweedie

Scott Tweedie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARING DIPHENYLUREIDO-DIHALOKYNURENIC ACIDS AND TOSYLATE ADDITION SALTS THEREOF
    Publication number: 20220162168
    Abstract: A method of preparing 5,7-dihalo-1,4-dihydro-4-oxoquinoline-2-carboxylic acid tosylate addition salts is provided, which involves direct conversion of esters of Formula V as described herein to acids of Formula VIII as described herein. Tosylate addition salts of Formula IX as described herein are then prepared from the acids of Formula VIII.
    Type: Application
    Filed: February 11, 2022
    Publication date: May 26, 2022
    Inventors: Ananya Sengupta, Sergiy KRASUTSKY, Scott TWEEDIE, Gurusankar RAMAMOORTHY
  • Continuous flow carboxylation reaction
    Patent number: 10899715
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: January 26, 2021
    Assignee: NOVARTIS AG
    Inventors: Scott Tweedie, Sripathy Venkatraman, James Zeller
  • Process for preparing 1,4-dihydro-4-oxoquinoline-2-carboxylates and 4-aminoquinoline compounds therefrom
    Patent number: 10875831
    Abstract: A method for preparing an alkyl 5,7-dihalo-1,4-dihydro-4-oxoquinoline-2-carboxylate ester is described herein. The method comprises cyclizing a compound of Formula III with Eaton's reagent in heated continuous flow reactor to form a compound of Formula IV wherein in Formula III and Formula IV, each X independently is a halogen atom; and each R independently is C1 to C4 alkyl. Optionally, a cosolvent such as dichloromethane can be included with the Eaton's reagent. A method of preparing a diphenylureido-dihalokynurenic acid alkyl ester of Formula VI from the compound of Formula IV also is described.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: December 29, 2020
    Assignee: Lohocla Research Corporation
    Inventors: Sergiy Krasutsky, Scott Tweedie, Gurusankar Ramamoorthy
  • CONTINUOUS FLOW CARBOXYLATION REACTION
    Publication number: 20190300485
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Application
    Filed: April 9, 2019
    Publication date: October 3, 2019
    Applicant: SARCODE BIOSCIENCE INC.
    Inventors: Scott Tweedie, Sripathy Venkatraman, James Zeller
  • Continuous flow carboxylation reaction
    Patent number: 10273212
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: April 30, 2019
    Assignee: SARCODE BIOSCIENCE INC.
    Inventors: Scott Tweedie, Sripathy Venkatraman, James Zeller
  • CONTINUOUS FLOW CARBOXYLATION REACTION
    Publication number: 20180118689
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Application
    Filed: June 28, 2017
    Publication date: May 3, 2018
    Applicant: SARCODE BIOSCIENCE INC.
    Inventors: Scott Tweedie, Sripathy Venkatraman, James Zeller
  • Continuous flow carboxylation reaction
    Patent number: 9725413
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: August 8, 2017
    Inventors: Scott Tweedie, Sripathy Venkatraman, James Zeller
  • CONTINUOUS FLOW CARBOXYLATION REACTION
    Publication number: 20160090361
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Application
    Filed: September 25, 2015
    Publication date: March 31, 2016
    Inventors: Scott Tweedie, Sripathy Venkatraman, Shuhong Liu, James Zeller, Elisabeth Brot, Michael Hamlin, Mary Newman, Mark McLaws, John Rosenberg, David Lathbury