Abstract: Provided herein are methods, systems, and devices for detecting and/or identifying one or more specific microorganisms in a culture sample. Indicator particles, such as surface enhanced Raman spectroscopy (SERS)-active nanoparticles, each having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest, can form a complex with specific microorganisms in the culture sample. Further, agitating magnetic capture particles also having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest can be used to capture the microorganism-indicator particle complex and concentrate the complex in a localized area of an assay vessel for subsequent detection and identification. The complex can be dispersed, pelleted, and redispersed so that the culture sample can be retested a number of times during incubation so as to allow for real-time monitoring of the culture sample.

Abstract: An injection system including a wearable component (e.g., a patch) adapted to be worn by a user, and a medication delivery component (e.g., injection device) configured to cooperate with the wearable component to deliver medication to the user. The wearable component can provide a target area to the user for targeting the medication delivery component during use, and further serve to prepare the injection site to minimize the potential for injection site reactions. Both the wearable component and the medication delivery component can include electronics and/or other devices for detecting and/or communication information regarding usage of the injection system including dose amount, frequency, time, etc. The system can be configured to communicate such information to a third party, such as a health care professional.

Abstract: Injection devices with ergonomic enhancements are disclosed. Generally, the injection devices include large oversized grips, including flanges at the base end of the device for enhanced stability. Push-type and squeeze-type devices are described, as well as manual injectors and auto-injectors. Such injection devices are useful for delivering a fluid (e.g. medication) to a patient.

Abstract: An article of manufacture embodiment comprises a sample cartridge including a sample substrate, and an enclosure including a sample ingress port. The enclosure mates with the sample cartridge to define a sample container containing the sample substrate which is accessible in the sample container via the sample ingress port. The sample cartridge including the sample substrate is removable from the sample container. A sampling method embodiment comprises disposing a sample on a sample substrate in a sample container and removing a sample cartridge including the sample substrate from the sample container. An article of manufacture embodiment comprises a sample substrate, a sample container containing the sample substrate and including a sample ingress port providing access to the sample substrate in the sample container, and a sample cartridge including the sample substrate. The sample cartridge including the sample substrate is removable as a unit from the sample container.

Abstract: The invention provides contact lens packages in which removal of the lens is facilitated by providing a means for elevating the lens when the package is opened.

Abstract: The invention provides contact lens packages in which removal of the lens is facilitated by elevating the lens when the package is opened.

Abstract: The invention provides contact lens packages in which removal of the lens is facilitated by providing a means for elevating the lens when the package is opened.

Abstract: An ophthalmic lens package comprises a shell having an internal cavity accessible through an opening in the shell and a drainage member that divides the internal chamber into an upper chamber and a lower chamber. The drainage member is permeable to aqueous liquids and is arranged to allow drainage of liquid from the upper chamber to the lower chamber. This arrangement of the ophthalmic lens package allows the consumer to retrieve the lens from the upper chamber without handling any significant amount of saline solution.

Abstract: An assembly mountable to an injector, such as an injection pen, to hide the needle of the injector from view. The assembly includes a retractable cover that is slidably mounted on a base sleeve that is releaseably connected to the injector. A spring between the cover and the base sleeve biases the cover toward a forward position at which it surrounds and hides the axially fixed needle from view.