Patents by Inventor Scott W. Martin
Scott W. Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11866430Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, and R4 are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK ?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: GrantFiled: June 26, 2019Date of Patent: January 9, 2024Assignee: Bristol-Myers Squibb CompanyInventors: Louis S. Chupak, Min Ding, Robert G. Gentles, Yazhong Huang, Scott W. Martin, Ivar M. Mcdonald, Stephen E. Mercer, Richard E. Olson, Upender Velaparthi, Michael Wichroski, Xiaofan Zheng
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Patent number: 11713316Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, R4, R5, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: GrantFiled: February 1, 2021Date of Patent: August 1, 2023Assignee: Bristol-Myers Squibb CompanyInventors: Upender Velaparthi, Louis S. Chupak, Chetan Padmakar Darne, Min Ding, Robert G. Gentles, Yazhong Huang, Manjunatha Narayana Rao Kamble, Scott W. Martin, Raju Mannoori, Ivar M. McDonald, Richard E. Olson, Hasibur Rahaman, Prasada Rao Jalagam, Saumya Roy, Gopikishan Tonukunuru, Sivasudar Velaiah, Jayakumar Sankara Warrier, Xiaofan Zheng, John S. Tokarski, Bireshwar Dasgupta, Kotha Rathnakar Reddy, Thiruvenkadam Raja
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Publication number: 20230089255Abstract: Provided are inhibitors of diacylglycerol kinases (DGK) and methods for treating diseases that would benefit from the stimulation of the immune system, such as cancer and infections diseases, comprising administering a DGK inhibitor in combination with an antagonist of the PD 1/PD-L 1 axis and/or an antagonist of CTLA4.Type: ApplicationFiled: December 18, 2020Publication date: March 23, 2023Inventors: Susan WEE, Joseph L. BENC, Xinyu WANG, Upender VELAPARTHI, Louis S. CHUPAK, Chatan P. DARNE, Min DING, Robert G. GENTLES, Yazhong HUANG, Scott W. MARTIN, Ivar M. MCDONALD, Richard E. OLSON, Xiaofan ZHENG, John S. TOKARSKI, Bireshwar DASGUPTA, Manjunatha Narayana Rao KAMBLE, Raju MANNOORI, Haslbur RAHAMAN, Prasada Rao JALAGAM, Saumya ROY, Gopikishan TONUKUNURU, Sivasudar VELAIAH, Jayakumar Sankara WARRIER, Kotha Rathnakar REDDY, Thiruvenkadam RAJA, Denise GRUNENFELDER, Michael WICHROSKI
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Publication number: 20220324859Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, R4, R5, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: ApplicationFiled: February 1, 2021Publication date: October 13, 2022Inventors: Upender Velaparthi, Louis S. Chupak, Chetan Padmakar Darne, Min Ding, Robert G. Gentles, Yazhong Huang, Manjunatha Narayana Rao Kamble, Scott W. Martin, Raju Mannoori, Ivar M. McDonald, Richard E. Olson, Hasibur Rahaman, Prasada Rao Jalagam, Saumya Roy, Gopikishan Tonukunuru, Sivasudar Velaiah, Jayakumar Sankara Warrier, Xiaofan Zheng, John S. Tokarski, Bireshwar Dasgupta, Kotha Rathnakar Reddy, Thiruvenkadam Raja
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Publication number: 20210277004Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, and R4 are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK ?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: ApplicationFiled: June 26, 2019Publication date: September 9, 2021Inventors: Louis S. Chupak, Min Ding, Robert G. Gentles, Yazhong Huang, Scott W. Martin, Ivar M. Mcdonald, Stephen E. Mercer, Richard E. Olson, Upender Velaparthi, Michael Wichroski, Xiaofan Zheng
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Publication number: 20210188845Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR6 or N; Y is CR3 or N; R1, R2, R3, R4, R5, R6, R7, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: ApplicationFiled: December 22, 2020Publication date: June 24, 2021Inventors: Robert G. Gentles, Upender Velaparthi, Min Ding, Richard E. Olson, Scott W. Martin, Saumya Roy, Prasada Rao Jalagam, Jayakumar Sankara Warrier, Louis S. Chupak, Denise Christine Grunenfelder
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Patent number: 10954238Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, R4, R5, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: GrantFiled: April 8, 2020Date of Patent: March 23, 2021Assignee: Bristol-Myers Squibb CompanyInventors: Upender Velaparthi, Louis S. Chupak, Chetan Padmakar Darne, Min Ding, Robert G. Gentles, Yazhong Huang, Manjunatha Narayana Rao Kamble, Scott W. Martin, Raju Mannoori, Ivar M. McDonald, Richard E. Olson, Hasibur Rahaman, Prasada Rao Jalagam, Saumya Roy, Gopikishan Tonukunuru, Sivasudar Velaiah, Jayakumar Sankara Warrier, Xiaofan Zheng, John S. Tokarski, Bireshwar Dasgupta, Kotha Rathnakar Reddy, Thiruvenkadam Raja
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Patent number: 10669272Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, R4, R5, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: GrantFiled: June 26, 2019Date of Patent: June 2, 2020Assignee: Bristol-Myers Squibb CompanyInventors: Upender Velaparthi, Louis S. Chupak, Chetan Padmakar Darne, Min Ding, Robert G. Gentles, Yazhong Huang, Manjunatha Narayana Rao Kamble, Scott W. Martin, Raju Mannoori, Ivar M. McDonald, Richard E. Olson, Hasibur Rahaman, Prasada Rao Jalagam, Saumya Roy, Gopikishan Tonukunuru, Sivasudar Velaiah, Jayakumar Sankara Warrier, Xiaofan Zheng, John S. Tokarski, Bireshwar Dasgupta, Kotha Rathnakar Reddy, Thiruvenkadam Raja
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Publication number: 20200109140Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, R4, R5, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.Type: ApplicationFiled: June 26, 2019Publication date: April 9, 2020Inventors: Upender VELAPARTHI, Louis S. Chupak, Chetan Padmakar Darne, Min Ding, Robert G. Gentles, Yazhong Huang, Manjunatha Narayana Rao Kamble, Scott W. Martin, Raju Mannoori, Ivar M. McDonald, Richard E. Olson, Hasibur Rahaman, Prasada Rao Jalagam, Saumya Roy, Gopikishan Tonukunuru, Sivasudar Velaiah, Jayakumar Sankara Warrier, Xiaofan Zheng, John S. Tokarski, Bireshwar Dasgupta, Kotha Rathnakar Reddy, Thiruvenkadam Raja
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Patent number: 10291417Abstract: A method and system for providing distributed network access point installation and management. A network provider installs and/or operates a plurality of access points at locations of a retail entity. Each access point may provide services such as Internet access, and/or content such as audio, video, text, and/or graphics, among other types of services. A carrier, such as a telephone or cable company, may compensate the network service provider for installation and operation of the access points. The carrier may in turn charge its subscribers for network access at the retail entity locations. A plurality of different carriers may provide compensation and allow respective subscriber access. The network access points may be configured to allow each carrier to present a point of presence to its subscribers at the retail entity locations. The installed network may also provide service for retail entity back office functions.Type: GrantFiled: December 19, 2007Date of Patent: May 14, 2019Assignee: WAYPORT, INC.Inventors: David J. Vucina, Gregory G. Williams, James D. Keeler, Scott W. Martin, Todd L. Mathis
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Patent number: 9850225Abstract: The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.Type: GrantFiled: April 8, 2015Date of Patent: December 26, 2017Assignee: Bristol-Myers Squibb CompanyInventors: Louis S. Chupak, Min Ding, Scott W. Martin, Xiaofan Zheng, Piyasena Hewawasam, Timothy P. Connolly, Ningning Xu, Kap-Sun Yeung, Juliang Zhu, David R. Langley, Paul Michael Scola
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Publication number: 20150291549Abstract: The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.Type: ApplicationFiled: April 8, 2015Publication date: October 15, 2015Inventors: Louis S. Chupak, Min Ding, Scott W. Martin, Xiaofan Zheng, Piyasena Hewawasam, Timothy P. Connolly, Ningning Xu, Kap-Sun Yeung, Juliang Zhu, David R. Langley, Daniel J. Tenney, Paul Michael Scola
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Patent number: 8143243Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.Type: GrantFiled: February 11, 2009Date of Patent: March 27, 2012Assignee: Bristol-Myers Squibb CompanyInventors: Scott W. Martin, Carl P. Bergstrom, Robert G. Gentles, Kap-Sun Yeung
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Patent number: 8133884Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.Type: GrantFiled: May 4, 2009Date of Patent: March 13, 2012Assignee: Bristol-Myers Squibb CompanyInventors: Scott W. Martin, Carl P. Bergstrom, Min Ding, Xiaofan Zheng, Robert G. Gentles
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Patent number: 7652004Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.Type: GrantFiled: July 28, 2008Date of Patent: January 26, 2010Assignee: Bristol-Myers Squibb CompanyInventors: Scott W. Martin, Carl P. Bergstrom, Robert G. Gentles, Kap-Sun Yeung
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Patent number: 7642251Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.Type: GrantFiled: August 1, 2008Date of Patent: January 5, 2010Assignee: Bristol-Myers Squibb CompanyInventors: Carl P. Bergstrom, Scott W. Martin
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Publication number: 20090280083Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.Type: ApplicationFiled: May 4, 2009Publication date: November 12, 2009Inventors: Scott W. Martin, Carl P. Bergstrom, Min Ding, Xiaofan Zheng, Robert G. Gentles
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Publication number: 20090275561Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.Type: ApplicationFiled: February 11, 2009Publication date: November 5, 2009Inventors: Scott W. Martin, Carl P. Bergstrom, Robert G. Gentles, Kap-Sun Yeung
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Patent number: 7521441Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.Type: GrantFiled: May 7, 2007Date of Patent: April 21, 2009Assignee: Bristol-Myers Squibb CompanyInventors: Robert G. Gentles, Piyasena Hewawasam, Min Ding, Carl P. Bergstrom, Scott W. Martin, Kap-Sun Yeung, Thomas W. Hudyma, Xiaofan Zheng, John A. Bender, John F. Kadow
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Publication number: 20090074715Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.Type: ApplicationFiled: July 28, 2008Publication date: March 19, 2009Inventors: Scott W. Martin, Carl P. Bergstrom, Robert G. Gentles, Kap-Sun Yeung