Abstract: The specification relates to compounds of Formula (1): and to pharmaceutically acceptable salts thereof, to processes and intermediates used for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of cancer.

Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.

Abstract: A patient containment system for securing a patient to a patient transport apparatus, comprising a first lower strap and a second lower strap. Each of the first lower strap and the second lower strap have a thigh region, a waist region, and a connection region arranged between the thigh region and the waist region. A first connector is coupled to the connection region of the first lower strap. A second connector is coupled to the connection region of the second lower strap, and is configured to releasably attach to the first connector to at least partially limit movement of the first lower strap relative to the second lower strap. The connection region defines a connection width, and the thigh region defines a thigh width larger than the connection width.

Abstract: A patient transport apparatus operable by a user for transporting a patient along stairs. A seat section is coupled to a support structure. A track having a belt is attached to the support structure and is arranged for selective operation between: a retracted position, and a deployed position to engage stairs. A drive system with a motor is disposed in rotational communication with the belt to control movement along stairs in the deployed position. A user interface us arranged for engagement to selectively adjust operation of the drive system between: an active state for controlling movement of the belt with the motor, and an inactive state. A braking controller is configured to sense movement of the belt in the inactive state, and to control the motor to limit movement of the belt in the inactive state to effect corresponding limited movement of the patient transport apparatus along stairs.

Abstract: Increases to the sensitivity of a probe magnet sensor are implemented for a camera lens. Probe magnet sensors may be located on carrier of a surface of an actuator coil to reduce the distance between the probe magnet sensor and a probe magnet mounted on an optics component that includes the camera lens. A probe magnet may be located within the camera so that the flux region of the probe magnet does not overlap with a flux region of a drive magnet for an actuator of the camera.

Abstract: An especially robust compound and its derivative metal complexes that are approximately one hundred-fold superior in catalytic performance to the previously invented TAML analogs is provided having the formula (I) wherein Y1, Y2, Y3 and Y4 are oxidation resistant groups which are the same or different and which form 5- or 6-membered rings with a metal, M, when bound to D; at least one Y incorporates a group that is significantly more stable towards nucleophilic attack than the organic amides of TAML activators; D is a metal complexing donor atom, preferably N; each X is a position for addition of a labile Lewis acidic substituent such as (i) H, deuterium, (ii) Li, Na, K, alkali metals, (iii) alkaline earth metals, transition metals, rare earth metals, which may be bound to one or more than one D, (iv) or is unoccupied with the resulting negative charge being balanced by a nonbonded counter-action; at least one Y may contain a site that is labile to acid dissociation, providing a mechanism for shortening compl

Abstract: A method, computer system, and a computer program product for dynamic internet of things (IoT) device grouping is provided. After an initial location of an IoT device is set, a current location of the IoT device is later determined. Thereafter, the determined current location is compared to the initial location. Responsive to determining that the current location does not match the initial location based on the comparing, a new IoT device group is assigned to the IoT device.

Abstract: A method, computer system, and a computer program product for dynamic internet of things (IoT) device grouping is provided. After an initial location of an IoT device is set, a current location of the IoT device is later determined. Thereafter, the determined current location is compared to the initial location. Responsive to determining that the current location does not match the initial location based on the comparing, a new IoT device group is assigned to the IoT device.

Abstract: Increases to the sensitivity of a probe magnet sensor are implemented for a camera lens. Probe magnet sensors may be located on carrier of a surface of an actuator coil to reduce the distance between the probe magnet sensor and a probe magnet mounted on an optics component that includes the camera lens. A probe magnet may be located within the camera so that the flux region of the probe magnet does not overlap with a flux region of a drive magnet for an actuator of the camera.

Abstract: Increases to the sensitivity of a probe magnet sensor are implemented for a camera lens. Probe magnet sensors may be located on carrier of a surface of an actuator coil to reduce the distance between the probe magnet sensor and a probe magnet mounted on an optics component that includes the camera lens. A probe magnet may be located within the camera so that the flux region of the probe magnet does not overlap with a flux region of a drive magnet for an actuator of the camera.

Abstract: A suspension spring may suspend an optical component for a camera or other device that implements the optical component to focus light being captured by an image sensor. The suspension spring may move along with the optical component that it suspends as a result of manual or automated focus changes that change the position of the optical component along an optical axis. The suspension spring may make contact with surfaces of other components or materials in the cameras or other systems. Those surfaces of the suspension spring that can make contact may be blunted to prevent the generation of loose particles that can interfere with the image sensor.

Abstract: An especially robust compound and its derivative metal complexes that are approximately one hundred-fold superior in catalytic performance to the previously invented TAML analogs is provided having the formula (I) wherein Y1, Y2, Y3 and Y4 are oxidation resistant groups which are the same or different and which form 5- or 6-membered rings with a metal, M, when bound to D; at least one Y incorporates a group that is significantly more stable towards nucleophilic attack than the organic amides of TAML activators; D is a metal complexing donor atom, preferably N; each X is a position for addition of a labile Lewis acidic substituent such as (i) H, denterium, (ii) Li, Na, K, alkali metals, (iii) alkaline earth metals, transition metals, rare earth metals, which may be bound to one or more than one D, (iv) or is unoccupied with the resulting negative charge being balanced by a nonhonded counter-action; at least one Y may contain a site that is labile to acid dissociation, providing a mechanism for shortening compl

Abstract: An especially robust compound and its derivative metal complexes that are approximately one hundred-fold superior in catalytic performance to the previously invented TAML analogs is provided having the formula: wherein Y1, Y2, Y3 and Y4 are oxidation resistant groups which are the same or different and which form 5- or 6-membered rings with a metal, M, when bound to D; at least one Y incorporates a group that is significantly more stable towards nucleophilic attack than the organic amides of TAML activators; D is a metal complexing donor atom, preferably N; each X is a position for addition of a labile Lewis acidic substituent such as (i) H, deuterium, (ii) Li, Na, K, alkali metals, (iii) alkaline earth metals, transition metals, rare earth metals, which may be bound to one or more than one D, (iv) or is unoccupied with the resulting negative charge being balanced by a nonbonded countercation; at least one Y may contain a site that is labile to acid dissociation, providing a mechanism for shortening co

Abstract: A low energy nitrogen removal wetland system is disclosed to provide high rates of nitrogen removal treatment for wastewater with low energy requirements. The wetland system uses down-flow rock-filled wetlands for nitrogen removal. The system has no aeration requirements, thus resulting in low energy consumption. The wetland system comprises a first column receiving drainage influent, a mid-level reservoir, a second column receiving drainage from the mid-level reservoir and a lower level reservoir receiving discharge from the second column. The first and the second columns are filled with media layers comprise rock media with ammonia adsorption capacity for ammonia removal. The wetland system operates in a flood and drain operation mode or a continuous flow mode.

Abstract: An aerated wetland system used for wastewater treatment is disclosed. The system includes a main frame with an entrance and an output opening. The wastewater is entered into the system with maximum velocity via the entrance and via a racetrack. The racetrack comprises an agitated flow pattern with a plurality of baffles along the longitudinal axis of the racetrack to deflect the wastewater and create turbulent flow into the wastewater. The racetrack further includes at least four intersecting sections. The at least two intersecting sections include washed soils and an aeration system and other two intersecting sections include washed soils and a plurality of wetland plants respectively, thereby subjecting the influent wastewater to anaerobic and aerobic conditions respectively, along the racetrack to effectively purify and treat volatile compounds in the influent wastewater. The outlet opening directs out effluent wastewater from the aerated wetland system via the effluent device.

Abstract: Increases to the sensitivity of a probe magnet sensor are implemented for a camera lens. Probe magnet sensors may be located on carrier of a surface of an actuator coil to reduce the distance between the probe magnet sensor and a probe magnet mounted on an optics component that includes the camera lens. A probe magnet may be located within the camera so that the flux region of the probe magnet does not overlap with a flux region of a drive magnet for an actuator of the camera.

Abstract: The invention relates to a solid filtering wastewater treatment device (100) comprising a first stage (101) with a freely drained fixed culture arranged directly above a second fixed water saturated culture stage (105), and a force aeration system (110) extending under the second stage. The invention also relates to a wastewater treatment method, as well as a process for sludge mineralization, implementing such a purification device.

Abstract: An aerated wetland system used for wastewater treatment is disclosed. The system includes a main frame with an entrance and an output opening. The wastewater is entered into the system with maximum velocity via the entrance and via a racetrack. The racetrack comprises an agitated flow pattern with a plurality of baffles along the longitudinal axis of the racetrack to deflect the wastewater and create turbulent flow into the wastewater. The racetrack further includes at least four intersecting sections. The at least two intersecting sections include washed soils and an aeration system and other two intersecting sections include washed soils and a plurality of wetland plants respectively, thereby subjecting the influent wastewater to anaerobic and aerobic conditions respectively, along the racetrack to effectively purify and treat volatile compounds in the influent wastewater. The outlet opening directs out effluent wastewater from the aerated wetland system via the effluent device.

Abstract: An especially robust compound and its derivative metal complexes that are approximately one hundred-fold superior in catalytic performance to the previously invented TAML analogs is provided having the formula: wherein Y1, Y2, Y3 and Y4 are oxidation resistant groups which are the same or different and which form 5- or 6-membered rings with a metal, M, when bound to D; at least one Y incorporates a group that is significantly more stable towards nucleophilic attack than the organic amides of TAML activators; D is a metal complexing donor atom, preferably N; each X is a position for addition of a labile Lewis acidic substituent such as (i) H, deuterium, (ii) Li, Na, K, alkali metals, (iii) alkaline earth metals, transition metals, rare earth metals, which may be bound to one or more than one D, (iv) or is unoccupied with the resulting negative charge being balanced by a nonbonded countercation; at least one Y may contain a site that is labile to acid dissociation, providing a mechanism for shortening co

Abstract: The invention relates to a solid filtering wastewater treatment device (100) comprising a first stage (101) with a freely drained fixed culture arranged directly above a second fixed water saturated culture stage (105), and a force aeration system (110) extending under the second stage. The invention also relates to a wastewater treatment method, as well as a process for sludge mineralization, implementing such a purification device.