Abstract: The present invention relates to novel mesylate salt of N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidine-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide, a novel crystalline form thereof, and a process for preparing the same. More specifically, the present invention relates to mesylate salt of N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidine-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide, which is excellent in stability, solubility, and bioavailability when it is administered not only alone but also in combination with other drugs and which has a high purity, a crystalline form thereof, and a process for preparing the same.

Abstract: The present invention relates to a 6-(isooxazolidin-2-yl)-N-phenylpyrimidin-4-amine derivative, and a pharmaceutical composition for preventing or treating cancer comprising the compound as an effective component. The compound exhibits high inhibitory activity against an epidermal growth factor receptor (EGFR) variant, or wild-type or variants of one or more of ERBB2 and ERBB4, and thus may be usefully used in the treatment of cancers in which same are expressed. In particular, the compound exhibits excellent inhibitory activity on proliferation of lung cancer cell lines, and thus can be usefully used in the treatment of lung cancer.

Abstract: Methods of fabricating semiconductor devices comprise forming first active patterns vertically spaced apart on a first active fin of a substrate and second active patterns vertically spaced apart on a second active fin of the substrate that has a first region on which the first active fin is formed and a second region on which the second active fin is formed, forming a first electrode layer on the first and second active fins and the first and second active patterns, forming a first mask pattern overlapping the first electrode layer on the first region, forming a second mask pattern overlapping the first electrode layer on the second region, and using the second mask pattern as an etching mask to etch the first mask pattern and the first electrode layer on the first region to form a first electrode pattern on the second region.

Abstract: According to one aspect of the present invention, a virtual reality control system for providing a chemical accident response training content includes a sensor detecting a light signal, a display displaying an image, at least one controller controlling the display, and a simulator displayed as a valve in the image, wherein the controller is configured to acquire first position data related to the user and second position data related to the simulator based on the light signal, acquire first virtual position data indicating a character corresponding to the user and acquire second virtual position data indicating the valve, and display the character and the valve on the display and display a gas within a predetermined distance from the valve, wherein at least a portion of the gas is not displayed when the character moves while at least a portion of the character is in contact with the valve.

Abstract: According to one aspect of the present disclosure, a virtual reality control system includes at least one controller configured to control at least one of the first display and the second display, the controller is configured to acquire first position data related to the first user and second position data related to the second user, and output an image including a first area and a second area to the first display on the basis of the first position data, if the first user has a first authority, the second user has a second authority and the first authority is a higher authority than the second authority, the first image is output to the first display when the first position data is located in the first area, and a notification image is output to the second display when the second position data is located in the first area.

Abstract: According to one aspect of the present disclosure, a virtual reality control system includes at least one controller configured to control at least one of the first display and the second display, the controller is configured to acquire first position data related to the first user and second position data related to the second user, and output an image including a first area and a second area to the first display on the basis of the first position data, if the first user has a first authority, the second user has a second authority and the first authority is a higher authority than the second authority, the first image is output to the first display when the first position data is located in the first area, and a notification image is output to the second display when the second position data is located in the first area.

Abstract: According to one aspect of the present invention, a virtual reality control system for providing a chemical accident response training content includes a sensor detecting a light signal, a display displaying an image, at least one controller controlling the display, and a simulator displayed as a valve in the image, wherein the controller is configured to acquire first position data related to the user and second position data related to the simulator based on the light signal, acquire first virtual position data indicating a character corresponding to the user and acquire second virtual position data indicating the valve, and display the character and the valve on the display and display a gas within a predetermined distance from the valve, wherein at least a portion of the gas is not displayed when the character moves while at least a portion of the character is in contact with the valve.