Patents by Inventor Sehoon Keum

Sehoon Keum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic mouse whose genome comprises a homozygous disruption of its ?1G gene, a method of preparing the same and use thereof
    Patent number: 7626076
    Abstract: The disclosure concerns a method for resistance of epilepsy by suppressing the function of alpha 1G protein of T-type calcium channels, use of suppressor of alpha 1G protein for prevention or treatment for epilepsy, knockout mice resisting epilepsy by disrupting alpha 1G subunit of T-type calcium channel, and preparation method thereof. The ?1G-knockout transgenic mouse can be used for investigating the relationship between diseases particularly neuropathy or psychopathy and the function of ?1G T-type calcium channel via various behavioral tests since ?1G subunit is mainly expression in central nervous system (CNS) and pheripheral nervous system (PNS). Further, the ?1G-knockout transgenic mouse can be used for screening antileptic agents.
    Type: Grant
    Filed: November 23, 2007
    Date of Patent: December 1, 2009
    Assignee: Orient Bio., Inc.
    Inventors: Hee-Sup Shin, Daesoo Kim, Sehoon Keum, Inseon Song
  • Transgenic mouse whose genome comprises a homozygous disruption of its alpha1G gene, a method of preparing the same and use thereof
    Publication number: 20080201787
    Abstract: The disclosure concerns a method for resistance of epilepsy by suppressing the function of alpha 1G protein of T-type calcium channels, use of suppressor of alpha 1G protein for prevention or treatment for epilepsy, knockout mice resisting epilepsy by disrupting alpha 1G subunit of T-type calcium channel, and preparation method thereof. The ?1G-knockout transgenic mouse can be used for investigating the relationship between diseases particularly neuropathy or psychopathy and the function of ?1G T-type calcium channel via various behavioral tests since ?1G subunit is mainly expression in central nervous system (CNS) and pheripheral nervous system (PNS). Further, the ?1G-knockout transgenic mouse can be used for screening antileptic agents.
    Type: Application
    Filed: November 23, 2007
    Publication date: August 21, 2008
    Inventors: Hee-Sup Shin, Daesoo Kim, Sehoon Keum, Inseon Song
  • Method of resistance of epilepsy by suppressing the function of alpha 1g protein
    Publication number: 20060025397
    Abstract: The disclosure concerns a method for resistance of epilepsy by suppressing the function of alpha 1 G protein of T-type calcium channels, use of suppressor of alpha 1 G protein for prevention or treatment for epilepsy, knockout mice resisting epilepsy by disrupting alpha 1 G subunit of T-type calcium channel, and preparation method thereof. In addition, suppressing alpha 1 G protein of T-type calcium channels does not occur epilepsy, and alpha 1 G-deficient mice are useful to study of mechanism related to epilepsy.
    Type: Application
    Filed: January 18, 2002
    Publication date: February 2, 2006
    Inventors: Hee-Sup Shin, Daesoo Kim, Sehoon Keum, Inseon Song