Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.

Abstract: In one example, a semiconductor device can comprise a substrate, a device stack, first and second internal interconnects, and an encapsulant. The substrate can comprise a first and second substrate sides opposite each other, a substrate outer sidewall between the first substrate side and the second substrate side, and a substrate inner sidewall defining a cavity between the first substrate side and the second substrate side. The device stack can be in the cavity and can comprise a first electronic device, and a second electronic device stacked on the first electronic device. The first internal interconnect can be coupled to the substrate and the device stack. The encapsulant can cover the substrate inner sidewall and the device stack and can fill the cavity. Other examples and related methods are disclosed herein.

Abstract: A display device according to an embodiment includes a substrate including an emission area and a non-emission area, a plurality of light emitting elements disposed on the substrate, a first electrode and a second electrode disposed to be spaced apart from each other and electrically connected to plurality of the light emitting elements, a cover layer disposed on the first electrode and the second electrode, and a color conversion layer disposed on the cover layer. The cover layer includes a plurality of sub-insulating layers each including a first layer and a second layer sequentially stacked. The first layer and the second layer have different refractive indices.

Abstract: A display device including: an insulating reflective layer on a substrate; and a light emitting element on the insulating reflective layer, wherein the insulating reflective layer includes a first layer and a second layer on the first layer, the first layer includes a first area of a shared layer that is at least a portion of the insulating reflective layer, the second layer includes a second area of the shared layer, the first layer includes a first distributed Bragg reflector configured to reflect light in a first wavelength band, and the second layer includes a second distributed Bragg reflector configured to reflect light in a second wavelength band.

Abstract: A display device including: a first electrode on a substrate, a second electrode spaced from the first electrode in a second direction, an optical layer on the first electrode and the second electrode, the optical layer including a first layer and a second layer, the second layer including a different material and having a different thickness from the first layer, and a plurality of light emitting elements on the optical layer, the first electrode, and the second electrode, wherein the optical layer includes a plurality of pair layers, each of the plurality of pair layers including the first layer and the second layer, and the first layer and the second layer are alternately stacked.

Abstract: The present invention relates to a composition for regulating circadian rhythms, a composition for diagnosing circadian rhythm disorders and a diagnostic kit, wherein the composition for regulating circadian rhythms comprises NQ peptides, C12orf39 genes, NQ peptides cDNA and the like, which relate to circadian regulation in vertebrates as main components.

Abstract: The present invention relates to a composition for regulating circadian rhythms, a composition for diagnosing circadian rhythm disorders and a diagnostic kit, wherein the composition for regulating circadian rhythms comprises NQ peptides, C12orf39 genes, NQ peptides cDNA and the like, which relate to circadian regulation in vertebrates as main components.