Abstract: The present invention relates to a method for inducing cardiomyocyte differentiation using a combination and/or composition of factors. The present invention also includes the combination and/or composition of factors. For example, the factors comprise at least one p38-MAPK modulator, at least one immunomodulator, at least one Wnt modulator and/or at least one ROS modulator. In particular, the factors comprise at least one p38-MAPK inhibitor, at least one immunosuppressant, at least one Wnt modulator and/or at least one ROS activator.

Abstract: The present invention relates to the field of cell differentiation. In particular, the present invention relates to a method for preparing improved cardiomyocyte-like cells differentiated from at least one multipotent or pluripotent cell, comprising a step of contacting the cardiomyocyte-like cell(s) with at least one agent to promote and/or induce integrin subunit alpha-V (integrin ?v) activity, thereby modulating expression of at least one cardiac gene of said cardiomyocyte-like cells. It also relates to a method for screening for an agent capable of improving cardiomyocytes differentiated from at least one multipotent or pluripotent cell.

Abstract: According to one aspect of the invention, there is provided an electrocardiographic monitoring system including: a housing configured to be attached to a creature body part, the housing including: a plurality of electrodes confined within the boundary of the housing, the plurality of electrodes arranged a distance apart from each other and accessible from a same exterior surface of the housing; a signal processor configured to receive signals from any one or more of the plurality of electrodes and transmit signals to any one or more of the plurality of electrodes; and a transmitter configured to transmit signals from the signal processor.

Abstract: There is presently provided a device for detecting an analyte particle in a sample. The device comprises a chamber having an interior surface upon which is located an electrode array. The electrode array comprises pairs of electrodes, each pair having an inner electrode and an outer electrode that substantially surrounds the inner electrode. Each pair of electrodes is coated with a capture molecule that recognises and binds the analyte particle that is to be identified and quantified. The device uses a combination of dielectrophoresis and impedance measurements to capture and measure analyte particles from a sample.