Abstract: Provided are a nucleic acid nanostructure including: a substrate; a nucleic acid quadruplex immobilized on the substrate to be vertical with respect to the substrate; a metal ion present in a unit lattice of the nucleic acid quadruplex, the unit lattice being made up of eight nucleobases; and a nanoparticle bound to an end of the nucleic acid quadruplex, and a method of manufacturing the same. According to the method, a nucleic acid nanostructure having an array of nanoparticles can be manufactured. The nucleic acid nanostructure can be applied as a sensor nanostructure for sensors such as gas sensors, chemical sensors, and biosensors. In particular, a nucleic acid nanostructure in which metal nanoparticles, e.g., gold or silver, are introduced can be useful as a device having local surface plasmon characteristics.

Abstract: Provided are a programmable mask for promptly fabricating a biomolecule or polymer array having high density, an apparatus for fabricating a biomolecule or polymer array including the mask, and a method of fabricating a biomolecule or polymer array using the programmable mask.

Abstract: Provided are a biomolecule detection device, a mobile phone for biomolecule detection, and a biomolecule detection method. The biomolecule detection device includes an electrophoresis unit comprising an electrophoretic gel filtering erythrocytes and leukocytes in blood and transferring proteins and DNAs in the blood, and at least one type of a probe biomolecule, immobilized in the electrophoretic gel, reacting with a target biomolecule; a conversion unit converting a result of a reaction between the target biomolecule and the probe biomolecule to an electrical signal; and a lead-out unit receiving, converting, and transmitting the electrical signal.

Abstract: A plasma apparatus is disclosed. The plasma apparatus includes an internal electrode having a hollow section for receiving precursor gas and oxygen gas therein, an external electrode accommodating the internal electrode therein while forming a gap therebetween in such a manner that inert gas and oxygen gas are introduced into the gap. The plasma apparatus also includes a power source for applying a DC voltage or a radio frequency (RF) AC voltage to the internal and external electrodes in order to generate plasma between the internal and external electrodes.

Abstract: A method for fabricating a multimode optical fiber preform having a longitudinal uniformity is provided. The method of fabricating includes performing a plurality of radial deposition passes using a thermal source while inserting raw materials into a glass tube. A reference chemical core shape index is set to determine a refractive index profile of a preform section. A core shape index distribution of each longitudinal deposition pass varying in a longitudinal direction of the glass tube is set such that an error of a reference chemical core shape index distribution in the longitudinal direction of the preform defined by the reference chemical core shape index is compensated for and such that a uniform chemical core shape index is obtained in the longitudinal direction. Deposition is performed while an amount of raw materials corresponding to a preset chemical core shape index is inserted in each longitudinal deposition pass of each radial deposition pass.

Abstract: A CMOS image sensor and fabricating method thereof are provided, in which a microlens is additionally formed on a planarizing layer prior to a color filter forming step and by which transmission efficiency of light incident on a photodiode enhances performance of the image sensor. The CMOS image sensor includes a plurality of photodiodes on a semiconductor substrate to be uniformly spaced apart from each other, an insulating interlayer on the semiconductor substrate including the photodiodes, a protective layer on the insulating interlayer, a plurality of first microlenses on the protective layer to correspond to the photodiodes, respectively, a first planarizing layer over the substrate including the first microlenses, a color filter layer on the first planarizing layer, a second planarizing layer over the substrate including the color filter layer, and a plurality of second microlenses on the second planarizing layer to correspond to the first microlenses, respectively.

Abstract: A row decoder circuit of a NAND flash memory and method of supplying an operating voltage using the same. To prevent an operating voltage (e.g., a program voltage, a pass voltage, or a read voltage) from being abnormally transferred to a gate of a memory cell because a pumping voltage is applied to a gate of a high-voltage pass transistor of the row decoder circuit in a level lower than a target voltage, the pumping voltage is first applied to the gate of the high-voltage pass transistor (i.e., precharging the gate of the high-voltage pass transistor) and next the operating voltage is applied to a drain of the high voltage pass transistor. Thus, the pumping voltage becomes higher than the target voltage due to a self-boosting effect through the structure of transistor, enabling the operating voltage to be normally transferred to the gate of the memory cell.

Abstract: The present invention relates to a programmable mask used in a photolithography process for fabricating a biomolecule array and a method of fabricating a biomolecule array using the same and, more particularly, to a programmable mask which can increase a contrast ratio of transmittance versus shielding of light incident to a liquid crystal which constitutes each pixel by irradiating parallel ultraviolet (“UV”) light generated from an external parallel light exposure device to a certain cell and using a vertically aligned liquid crystal panel or an LC panel having no spacer, and a method of fabricating a biomolecule array using the same.

Abstract: A humanized antibody of the present invention shows similar antigen-binding affinity to a mouse monoclonal antibody and significantly low immunogenecity. Therefore, the humanized antibody of the present invention can be effectively used for treating chronic hepatitis B and preventing HBV infection of a patient received liver transplantation and vertical transmission from a mother infected with HBV to a fetus.

Abstract: A plastic optical fiber and a method for producing the same is disclosed. The plastic optical fiber is formed as a fiber of core-cladding structure. A protective layer or shield layer may be provided on the outer surface of the optical fiber of core-cladding structure for improving thermal resistance of the optical fiber and protecting the optical fiber from air and moisture. The plastic optical fiber uses fluorinated plastic, which contains a rare earth component as a core material, and a cladding material, which does not comprise a rare earth component but essentially consists of a polymer chain, which essentially consists of bonded —[CF2]n— monomers and has a refractive index lower than that of the core material. The optical fiber is produced by a melting-drawing technique.

Abstract: Provided is a micro-fluidic heating system, which comprises a micro-fluidic control element for providing a chamber, a flow path and a valve, and a main body for heating the inside of the chamber in contact with the micro-fluidic control element, wherein the micro-fluidic control element consists of an upper substrate for providing the chamber, the flow path and the valve, and a lower substrate as a thin film bonded to the upper substrate, and the main body consists of a membrane in which heating means and suction holes are formed, and support member for supporting the membrane, and the heating means is partially in contact with the lower substrate of the chamber to heat the inside of the chamber, so that thermal transfer efficiency becomes maximized and temperature of each chamber may be independently controlled in the case of configuration having chambers arranged in array.

Abstract: Provided are a plastic microfabricated structure, and a microfabricated thermal device, a microfabricated reactor, a microfabricated reactor array and a micro array using the same, which may be applied to a bio chip, and the present invention may fabricate the plastic microfabricated structure for providing a heating region by means of insulating plastic, which has a thin thickness, flatness enough to allow a photolithography process to be performed, thermal isolation in its some or total area, and a small thermal mass, and on top of the heating region of the plastic microfabricated structure, a heater, a temperature sensor for sensing a temperature, an electrode, and an electrode pad are formed to thereby fabricate the microfabricated heating device, whereby element may be readily fabricated at a low cost, and the heating region is formed of a plastic thin layer, so that uniform temperature control is possible even with a low power, and various samples may be thermally treated at a fast speed to obtain their

Abstract: An object of the present invention is to provide a method that is capable of forming easily a fine pattern corresponding to a high integration density device, without using a new exposure apparatus. The object of the present invention as noted above is accomplished by etching a second insulating layer to expose a portion of an underlying first insulating layer; forming a third insulating layer on the entire surface of the substrate; etching the third insulating layer and the first insulating layer using the second insulating layer as an etch barrier, to define a pattern region; forming a material layer on the entire surface of the substrate so as to fill the pattern region; and planarizing the material layer and/or substrate so as to expose the first insulating layer, to form a pattern.

Abstract: Provided is a microfluidic control device and method for controlling the microfluid, and a fine amount of fluid is controlled even with natural fluid flow and solution injection, wherein a pressure barrier of a capillary is removed by a surface tension change resulted from the solution injection to thereby obtain transport, interflow, mixing, and time delay of the microfluid, and to detail this, solution is injected to meet the boundary surface of the stopped fluid when the fluid is stopped by the stop valve, so that a function of the stop valve is removed to obtain the transport, interflow, and mixing of the fluid, and the method for controlling the microfluid may be applied to the microfluidic control device for biochemical reaction, and it uses only the capillary force change resulted from solution injection to thereby have its structure simplified.