Abstract: Described are anti-doppel antibody-drug conjugates, compositions comprising them, and related methods of treating doppel-associated diseases and conditions, including cancer.

Abstract: Described herein are doppel-targeting molecules (e.g., antibodies) useful for inhibiting pathological angiogenesis and treating diseases and conditions associated with pathological angiogenesis, such as tumors, cancers, atherosclerosis, tuberculosis, asthma, pulmonary arterial hypertension (PAH), neoplasms and neoplasm-related conditions, and for detecting doppel expression in a subject. Related compositions and methods also are described.

Abstract: The present invention relates to a monoclonal antibody binding specifically to YKL-40. A high expression level of YKL-40 is associated with the proliferation and metastasis of cancer and a monoclonal antibody against YKL-40 exhibits an effect of inhibiting the proliferation and metastasis of cancer. Thus, the monoclonal antibody of the present disclosure can be advantageously used for diagnosing, preventing or treating cancer.

Abstract: Described herein are doppel-targeting molecules (e.g., antibodies) useful for inhibiting pathological angiogenesis and treating diseases and conditions associated with pathological angiogenesis, such as tumors, cancers, atherosclerosis, tuberculosis, asthma, pulmonary arterial hypertension (PAH), neoplasms and neoplasm-related conditions, and for detecting doppel expression in a subject. Related compositions and methods also are described.

Abstract: The present invention provides biaryl- or heterocyclic biaryl-substituted cyclohexene derivative compounds, isomers thereof, or pharmaceutically acceptable salts. The compounds of the invention show a CETP inhibitory effect that increases HDL-cholesterol levels and reduces LDL-cholesterol levels. Pharmaceutical compositions comprising the compounds are useful for the prevention or treatment of dyslipidemia or dyslipidemia-related diseases.

Abstract: The present invention provides biaryl- or heterocyclic biaryl-substituted cyclohexene derivative compounds, isomers thereof, or pharmaceutically acceptable salts. The compounds of the invention show a CETP inhibitory effect that increases HDL-cholesterol levels and reduces LDL-cholesterol levels. Pharmaceutical compositions comprising the compounds are useful for the prevention or treatment of dyslipidemia or dyslipidemia-related diseases.

Abstract: The present invention provides biaryl- or heterocyclic biaryl-substituted cyclohexene derivative compounds, isomers thereof, or pharmaceutically acceptable salts. The compounds of the invention show a CETP inhibitory effect that increases HDL-cholesterol levels and reduces LDL-cholesterol levels. Pharmaceutical compositions comprising the compounds are useful for the prevention or treatment of dyslipidemia or dyslipidemia-related diseases.

Abstract: A display apparatus, a power supply apparatus and a power supply method thereof are provided. The display apparatus includes: a signal processor which processes an image signal; a display unit which displays thereon an image corresponding to the processed image signal; and a power supply unit which receives an input of AC power and supplies operating power to the display unit. The power supply unit includes a discharging circuit unit which discharges a remaining voltage of the power supply unit if the input of the AC power is suspended, and does not discharge the voltage if the AC power is input. Accordingly, a remaining voltage from a power supply unit is effectively removed if an input of AC power is suspended, and power consumption does not occur if the AC power is input.

Abstract: A display apparatus and a power supplying method are provided. The display apparatus includes a signal receiver which receives a video signal; a signal processor which processes the video signal; a display unit which displays an image based on a video signal processed by the signal processor; and a power supply which converts an alternating current (AC) voltage into a direct current (DC) voltage and supplies an operation voltage to the display unit, the power supply including: a power factor correction (PFC) unit which adjusts the DC voltage and corrects a power factor of the power supply; a detector which detects a plurality of voltages in the power supply and outputs a common detection signal indicating whether at least one of the plurality of voltages is abnormal; and a controller which receives the common detection signal, and controls the PFC unit based on the common detection signal.

Abstract: An image forming apparatus includes a plurality of optical scanning units to scan light modulated according to an image signal, a plurality of photoconductive drums to form a plurality of electrostatic latent images by the light scanned from the plurality of optical scanning units, a plurality of developing units to develop the plurality of electrostatic latent images formed on the plurality of photoconductive drums into a plurality of toner images, an intermediate transfer unit to transfer the plurality of toner images developed by the plurality of developing units, a plurality of first transfer rollers installed in the intermediate transfer unit to correspond to the plurality of photoconductive drums, respectively, and to apply transfer voltages that is used to transfer the plurality of toner images onto the intermediate transfer unit, a second transfer roller to transfer the plurality of toner images formed on the intermediate transfer unit onto a paper, and a fixing unit to fix the plurality of toner imag

Abstract: A display apparatus, a power supply apparatus and a power supply method thereof are provided. The display apparatus includes: a signal processor which processes an image signal; a display unit which displays thereon an image corresponding to the processed image signal; and a power supply unit which receives an input of AC power and supplies operating power to the display unit. The power supply unit includes a discharging circuit unit which discharges a remaining voltage of the power supply unit if the input of the AC power is suspended, and does not discharge the voltage if the AC power is input. Accordingly, a remaining voltage from a power supply unit is effectively removed if an input of AC power is suspended, and power consumption does not occur if the AC power is input.

Abstract: A display apparatus and a power supplying method are provided. The display apparatus includes a signal receiver which receives a video signal; a signal processor which processes the video signal; a display unit which displays an image based on a video signal processed by the signal processor; and a power supply which converts an alternating current (AC) voltage into a direct current (DC) voltage and supplies an operation voltage to the display unit, the power supply including: a power factor correction (PFC) unit which adjusts the DC voltage and corrects a power factor of the power supply; a detector which detects a plurality of voltages in the power supply and outputs a common detection signal indicating whether at least one of the plurality of voltages is abnormal; and a controller which receives the common detection signal, and controls the PFC unit based on the common detection signal.

Abstract: An image forming apparatus includes a plurality of optical scanning units to scan light modulated according to an image signal, a plurality of photoconductive drums to form a plurality of electrostatic latent images by the light scanned from the plurality of optical scanning units, a plurality of developing units to develop the plurality of electrostatic latent images formed on the plurality of photoconductive drums into a plurality of toner images, an intermediate transfer unit to transfer the plurality of toner images developed by the plurality of developing units, a plurality of first transfer rollers installed in the intermediate transfer unit to correspond to the plurality of photoconductive drums, respectively, and to apply transfer voltages that is used to transfer the plurality of toner images onto the intermediate transfer unit, a second transfer roller to transfer the plurality of toner images formed on the intermediate transfer unit onto a paper, and a fixing unit to fix the plurality of toner imag

Abstract: An image forming apparatus includes at least one supporting roller, a movable belt supported by the supporting roller, and a shifting restricting unit to prevent the movable belt from shifting to any one side along an axial direction of the supporting roller. The shifting restricting unit includes a guide rail formed between the movable belt and the supporting roller to guide movement of one end of the movable belt, and a belt pressurizing member formed at the other end of the movable belt to generate tension on the movable belt to compensate for a shifting force on the guide rail side by the guide rail.

Abstract: An image forming apparatus includes a moving unit which includes a conveyer belt to move a recording medium, an attraction unit which is disposed at a front head in a moving direction of the recording medium and attracts the recording medium to the conveyer belt, a plurality of transferring units including a photosensitive material and a transfer roller to perform a transferring process of the recording medium according to a plurality of colors, a power supply to supply power to form an electric field in the transferring unit and the attraction unit to perform transfer and attraction of the recording medium, and a controller to control the power supply to supply the power to the plurality of transferring units corresponding to resistance values of second transferring units among the plurality of transferring units, the second transferring units disposed apart from a first transferring unit that is located closest to the attraction unit with respect to the moving direction of the recording medium.

Abstract: A standby power supply apparatus is provided in which a supply voltage of the standby power source, supplied before electronic apparatuses such as TVs or video players are switched on, is reduced by half to sharply reduce the consumption of the standby electric power. According to the standby power supply apparatus, it is possible to reduce by half the electric power loss due to switching the standby power converter controlling the standby electric power of the power supply apparatus on and off. Additionally, the standby electric power can be sharply reduced without an additional increase in manufacturing costs of the power supply apparatus.

Abstract: A transfer unit of an image forming apparatus includes at least one support roller; a transfer belt driven and supported by the support roller; and a meander preventing unit to prevent the transfer belt from leaning to one side with respect to an axial direction of the support roller. The meander preventing unit includes a guide rail disposed between one side of the belt and the support roller supporting the belt to guide the belt running; and a belt pressing member disposed on the opposite side of the belt to compensate for the belt leaning caused by the guide rail.

Abstract: An image forming apparatus includes a moving unit which includes a conveyer belt to move a recording medium, an attraction unit which is disposed at a front head in a moving direction of the recording medium and attracts the recording medium to the conveyer belt, a plurality of transferring units including a photosensitive material and a transfer roller to perform a transferring process of the recording medium according to a plurality of colors, a power supply to supply power to form an electric field in the transferring unit and the attraction unit to perform transfer and attraction of the recording medium, and a controller to control the power supply to supply the power to the plurality of transferring units corresponding to resistance values of second transferring units among the plurality of transferring units, the second transferring units disposed apart from a first transferring unit that is located closest to the attraction unit with respect to the moving direction of the recording medium.

Abstract: A standby power supply apparatus is provided in which a supply voltage of the standby power source, supplied before electronic apparatuses such as TVs or video players are switched on, is reduced by half to sharply reduce the consumption of the standby electric power. According to the standby power supply apparatus, it is possible to reduce by half the electric power loss due to switching the standby power converter controlling the standby electric power of the power supply apparatus on and off. Additionally, the standby electric power can be sharply reduced without an additional increase in manufacturing costs of the power supply apparatus.

Abstract: An image forming apparatus includes at least one supporting roller, a movable belt supported by the supporting roller, and a shifting restricting unit to prevent the movable belt from shifting to any one side along an axial direction of the supporting roller. The shifting restricting unit includes a guide rail formed between the movable belt and the supporting roller to guide movement of one end of the movable belt, and a belt pressurizing member formed at the other end of the movable belt to generate tension on the movable belt to compensate for a shifting force on the guide rail side by the guide rail.