Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: In various embodiments nanoparticle drug delivery vehicles are provided herein for the effective delivery of a GSK3 inhibitor. In certain embodiments the drug delivery vehicle comprises a nanoparticle comprising one or more cavities disposed within the nanoparticle and an outside surface where the one or more cavities are in fluid communication the outside surface of the nanoparticle; a GSK3 inhibitor disposed within said one or more cavities; and a lipid bilayer disposed on the surface of said nanoparticle where said lipid bilayer fully encapsulates said nanoparticle.

Abstract: Processing a payment transaction from a payer (operating a payer computing system) to a payee (operating a merchant computing system) by a secure computing system. The secure computing system outputs a financial account registration request form to the payer computing system (e.g., within a window or frame that is displayed within an ecommerce webpage provided by the merchant computing system) for the payer to provide sensitive financial account information, securely stores the sensitive financial account information, maintains compliance with an information security standard (e.g., a Payment Card Industry Data Security Standard), and provides a non-sensitive electronic data token representing the sensitive financial account information to the merchant computing system.

Abstract: In various embodiments immunogenic nanoparticles are provided that are capable of raising an immune response directed against one or more viral proteins and/or protein fragments. In certain embodiments the immunogenic nanoparticles raise an immune response directed against a virus (e.g., SARS-CoV-2 (2019-nCoV), SARS-CoV-2, and MERS-CoV, and the like). In certain embodiments the immunogenic nanoparticles comprise a nanoparticle formed from one or more biocompatible polymer(s), one or more viral proteins or fragments thereof encapsulated within or attached to the biocompatible polymer(s) where the viral protein or fragment thereof comprises an antigen to which an immune response is to be induced by administration of the immunogenic nanoparticle to a mammal and where the immunogenic nanoparticle further comprises an adjuvant (e.g., a STING agonist).

Abstract: Processing a payment from a payer to a payee (operating a first computing system), by a second computing system, by receiving an electronically-generated payment transaction instruction (identifying the payer, specifying the amount of the payment, and specifying a communications link for the second computing system to obtain financial account information from the payer) from the first computing system, obtaining the financial account information from the payer via the specified communications link, generating an electronic data token representing the financial account information, outputting the electronic data token for transmittal to the first computing system (where the first computing system does not receive the financial account information and the second computing system does not provide the electronic data token to the payer), obtaining the amount from the payer using the financial account information, and forwarding at least a portion of the amount to the payee.

Abstract: An engine oil lubrication system includes an oil flow control baffle disposed in the sump of the oil pan. The baffle may be detachably mountable in the sump of the oil pan. The baffle may be configured to prevent oil returning to the sump from the engine from short-circuiting and flowing directly to the oil pump intake. The baffle creates a circuitous flow path which forces mixing of the returning oil before being drawn into the oil pump intake nozzle via increasing resonance time of the oil in the sump to enhance cooling. The present disclosure further provides a modular engine mounting system which extends the number of engines and vehicle chassis which can utilize a single oil pan to mount to the chassis. Interchangeable mounting flanges are provided having different bolting patterns compatible with the different chassis.

Abstract: A system comprising a hosting service configured to perform: providing, to a trusted entity on a central processing unit, a command for a launch of a virtual machine (VM); assigning, to the VM, at least a portion of memory for the guest operating system; submitting, to the trusted entity, a request to measure an address space of the VM to provide a measurement digest of the address space of the guest operating system; including, in a configuration object, a policy provided by the user for the service logic, wherein the policy defines one or more rules for the service logic, wherein the one or more rules include at least one rule for which containers may run in the guest operating system; hashing the policy to provide a hash digest of the policy; submitting, to the trusted entity, the hash digest of the policy; and completing the launch of the VM.

Abstract: An engine oil lubrication system includes an oil flow control baffle disposed in the sump of the oil pan. The baffle may be detachably mountable in the sump of the oil pan. The baffle may be configured to prevent oil returning to the sump from the engine from short-circuiting and flowing directly to the oil pump intake. The baffle creates a circuitous flow path which forces mixing of the returning oil before being drawn into the oil pump intake nozzle via increasing resonance time of the oil in the sump to enhance cooling. The present disclosure further provides a modular engine mounting system which extends the number of engines and vehicle chassis which can utilize a single oil pan to mount to the chassis. Interchangeable mounting flanges are provided having different bolting patterns compatible with the different chassis.

Abstract: An engine oil lubrication system includes an oil flow control baffle disposed in the sump of the oil pan. The baffle may be detachably mountable in the sump of the oil pan. The baffle may be configured to prevent oil returning to the sump from the engine from short-circuiting and flowing directly to the oil pump intake. The baffle creates a circuitous flow path which forces mixing of the returning oil before being drawn into the oil pump intake nozzle via increasing resonance time of the oil in the sump to enhance cooling. The present disclosure further provides a modular engine mounting system which extends the number of engines and vehicle chassis which can utilize a single oil pan to mount to the chassis. Interchangeable mounting flanges are provided having different bolting patterns compatible with the different chassis.

Abstract: A system for assessing stroke conditions includes a wearable stimulator and a sensor device configured to obtain physiological data from a patient. The sensor device can include electrodes configured to detect electrical signals corresponding to brain activity. A computing device communicatively coupled to the wearable stimulator and the sensor device is configured to receive the physiological data and analyze the physiological data to provide a patient stroke assessment.

Abstract: The present invention relates to a system for delivering medical services in a mobile setting that includes a frame assembly, where said frame assembly is mounted to an enclosed portable compartment. The frame assembly forms an examination and therapy area for administering a multitude therapy modalities. The therapy area includes a plurality of tables convertibly and plurality of cabinets integrated into the frame assembly. A grouping of training equipment removably engages with the frame assembly related to various therapy techniques. The enclosed portable compartment may be an interior of a van or an interior of a portable pod.

Abstract: A measurement system and methods for collecting measurement data for features of ceramic matrix composite (CMC) components are provided. In one aspect, the system and methods provided herein can be utilized to collect measurement data for a cooling hole of a CMC component. The measurement system includes a sensor system that includes a chromatic confocal sensor and a charged coupled device. The chromatic confocal sensor emits stacked cones of light each having an associated wavelength. The stacked cones are moved over a target surface of the CMC component and the charged coupled device measures one or more characteristics associated with the reflected light. The characteristics are then used by a computing device to generate a measurement data file representative of the geometric profile of the cooling hole. A rotary table system can position the CMC component to present the cooling hole at different orientations.

Abstract: A measurement system and methods for collecting measurement data for features of ceramic matrix composite (CMC) components are provided. In one aspect, the system and methods provided herein can be utilized to collect measurement data for a cooling hole of a CMC component. The measurement system includes a sensor system that includes a chromatic confocal sensor and a charged coupled device. The chromatic confocal sensor emits stacked cones of light each having an associated wavelength. The stacked cones are moved over a target surface of the CMC component and the charged coupled device measures one or more characteristics associated with the reflected light. The characteristics are then used by a computing device to generate a measurement data file representative of the geometric profile of the cooling hole. A rotary table system can position the CMC component to present the cooling hole at different orientations.

Abstract: Processing a payment from a payer to a payee (operating a first computing system), by a second computing system, by receiving an electronically-generated payment transaction instruction (identifying the payer, specifying the amount of the payment, and specifying a communications link for the second computing system to obtain financial account information from the payer) from the first computing system, obtaining the financial account information from the payer via the specified communications link, generating an electronic data token representing the financial account information, outputting the electronic data token for transmittal to the first computing system (where the first computing system does not receive the financial account information and the second computing system does not provide the electronic data token to the payer), obtaining the amount from the payer using the financial account information, and forwarding at least a portion of the amount to the payee.

Abstract: Methods for sharing mini-games over a game cloud system include receiving a request from a first user to access a user account managed by the game cloud system. Access to the user account is provided, in response to the request. Providing access includes presenting a user interface with a plurality of mini-games available to the user account for user interaction, on a client device of the first user. The plurality of mini-games includes mini-games that have been shared and mini-games that have not been shared with other users. The method further includes detecting selection of a particular mini-game at the user interface. In response to detecting selection, an option to share the particular mini-game with other users, is provided. The option allows the first user to post the particular mini-game to a social stream of the other users.

Abstract: A steam turbine inlet assembly and method of constructing the same are disclosed. In an embodiment, an annular ring is provided, along with a body affixed to a distal face of the annular ring and extending distally therefrom. The body portion has a curved entrance geometry at the proximal end adjacent the annular ring, and transitions to a substantially polygonal exit geometry at a distal end.

Abstract: A session to enroll customers to make payments has two stages, a first stage completed on the telephone or on a merchant or debt collector website, and a second stage completed via a communications link such as a telephone or Internet link. The customer enrollment record is linked to financial account information received from the customer in the second stage and stored on a second, secure server. A token linked to the securely stored financial account information is returned to the merchant and then used by the merchant to initiate payments on that financial account. The merchant's personnel and customer record system do not store or have access to the underlying financial account information.

Abstract: Methods for sharing mini-games over a game cloud system include receiving a request from a first user to access a user account managed by the game cloud system. Access to the user account is provided, in response to the request. Providing access includes presenting a user interface with a plurality of mini-games available to the user account for user interaction, on a client device of the first user. The plurality of mini-games includes mini-games that have been shared and mini-games that have not been shared with other users. The method further includes detecting selection of a particular mini-game at the user interface. In response to detecting selection, an option to share the particular mini-game with other users, is provided. The option allows the first user to post the particular mini-game to a social stream of the other users.