Patents by Inventor Sean C. Proll

Sean C. Proll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Manipulation of Cytokine Levels Using CD83 Gene Products
    Publication number: 20110144309
    Abstract: The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.
    Type: Application
    Filed: November 8, 2010
    Publication date: June 16, 2011
    Applicant: Celltech R&D, Inc.
    Inventors: Fred Ramsdell, Sean C. Proll, Karen Staehling-Hampton, Mark W. Appleby, Leon Fernando Garcia-Martinez
  • Manipulation of cytokine levels using CD83 gene products
    Patent number: 7850968
    Abstract: The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: December 14, 2010
    Assignee: Celltech R&D Limited
    Inventors: Fred Ramsdell, Sean C Proll, Karen Staehling-Hampton, Mark W. Appleby, Leon Fernando Garcia-Martinez
  • Manipulation of Cytokine Levels Using CD83 Gene Products
    Publication number: 20100081797
    Abstract: The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.
    Type: Application
    Filed: October 2, 2009
    Publication date: April 1, 2010
    Applicant: CELLTECH R&D, INC.
    Inventors: Fred Ramsdell, Sean C. Proll, Karen Staehling-Hampton, Mark W. Appleby, Leon Fernando Garcia-Martinez
  • Manipulation of cytokine levels using CD83 gene products
    Patent number: 7618629
    Abstract: The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.
    Type: Grant
    Filed: November 21, 2002
    Date of Patent: November 17, 2009
    Assignee: Celltech R&D, Inc.
    Inventors: Fred Ramsdell, Sean C. Proll, Karen Staehling-Hampton, Mark W. Appleby, Leon Fernando Garcia-Martinez