Patents by Inventor Sean Chow

Sean Chow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11065115
    Abstract: Prosthetic heart valves are described. Prosthetic heart valves can include radially expandable and compressible inner and outer metal frames. The inner frame can be disposed within a lumen of the outer frame and can be coupled to the outer frame. An outflow end of the inner frame can be coupled to and/or located at an outflow end of the outer frame. An end portion of the inner frame can be spaced radially inwardly from an inner surface of the outer frame, such that a radial gap exists between the inner surface of the outer frame and an outer surface of the inner frame. Prosthetic heart valves can further include a plurality of leaflets disposed within and supported by the inner frame, such as by commissure posts of the inner frame.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: July 20, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Netanel Benichou, Stanton J. Rowe, Sean Chow
  • Patent number: 11026781
    Abstract: Anchor devices and methods can be used to secure a prosthetic valve to a native valve annulus. The anchor device can be a separate expandable element from the prosthetic valve that is first advanced to the annulus and deployed, after which an expandable prosthetic valve is advanced to within the annulus and deployed. The combination of the two elements can apply a clamping force to the valve leaflets which holds the prosthetic valve in place. The anchor device can have a lower or ventricular portion and an upper or atrial portion. The anchor device can include one or more leaflet clamping portions. One, two, or more upstanding vertical posts between the clamping portions can extend upward at the valve commissures and support the upper portion, which can include one or more structures for leak prevention.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: June 8, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Dustin P. Armer, Sean Chow, Jenny Nguyen, Emil Karapetian, Tri D. Tran
  • Patent number: 11013600
    Abstract: A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.
    Type: Grant
    Filed: January 21, 2019
    Date of Patent: May 25, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Evan T. Schwartz, Sean Chow, Sandip Vasant Pawar, Darshin S. Patel, Chambory Chhe, Arpit Laddha, Ngoc Huong Thi Nguyen, Waina Michelle Chu, Yuanlong Du, Michael Bukin, Boaz Manash, Sara Haivatov, Tamir S. Levi
  • Publication number: 20210085458
    Abstract: A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion. The shaft is configured such that a fluid can flow through the lumen and the openings. The inner balloon has end portions and a center portion disposed between the end portions. The inner balloon is mounted on the distal end portion of the shaft and is in fluid communication with the openings of the shaft. When the inner balloon is inflated with the fluid, the end portions expand farther radially outwardly than the center portion. The outer balloon is mounted to the shaft and disposed over the inner balloon. The outer balloon is configured to fully expand after the inner balloon at least partially expands.
    Type: Application
    Filed: December 3, 2020
    Publication date: March 25, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Ronaldo C. Cayabyab, David J. Evans, Sean Chow, Christopher Chia, Tamir S. Levi
  • Publication number: 20210001090
    Abstract: In one representative embodiment, a steerable catheter device comprises a shaft comprising a proximal portion and a distal portion, and first and second pull wires having respective proximal portions and respective distal portions. The proximal portions of the first and second pull wires extend through the proximal portion of the shaft in close proximity to each other. The distal portions of the first and second pull wires extend through the distal portion of the shaft in close proximity to each other over a first distance defining a primary flexing section, diverge away from each other over a second distance, and then extend parallel to each other at angularly spaced locations over a third distance defining a secondary flexing section.
    Type: Application
    Filed: September 21, 2020
    Publication date: January 7, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Sean Chow, Ronaldo C. Cayabyab
  • Patent number: 10856977
    Abstract: A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion. The shaft is configured such that a fluid can flow through the lumen and the openings. The inner balloon has end portions and a center portion disposed between the end portions. The inner balloon is mounted on the distal end portion of the shaft and is in fluid communication with the openings of the shaft. When the inner balloon is inflated with the fluid, the end portions expand farther radially outwardly than the center portion. The outer balloon is mounted to the shaft and disposed over the inner balloon. The outer balloon is configured to fully expand after the inner balloon at least partially expands.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: December 8, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Ronaldo C. Cayabyab, David J. Evans, Sean Chow, Christopher Chia, Tamir S. Levi
  • Publication number: 20200368018
    Abstract: Prosthetic heart valves are described. Prosthetic heart valves can include radially expandable and compressible inner and outer metal frames. The inner frame can be disposed within a lumen of the outer frame and can be coupled to the outer frame. An outflow end of the inner frame can be coupled to and/or located at an outflow end of the outer frame. An end portion of the inner frame can be spaced radially inwardly from an inner surface of the outer frame, such that a radial gap exists between the inner surface of the outer frame and an outer surface of the inner frame. Prosthetic heart valves can further include a plurality of leaflets disposed within and supported by the inner frame, such as by commissure posts of the inner frame.
    Type: Application
    Filed: August 13, 2020
    Publication date: November 26, 2020
    Applicant: Edwards Lifesciences Corporation
    Inventors: Netanel Benichou, Stanton J. Rowe, Sean Chow
  • Patent number: 10792467
    Abstract: In one representative embodiment, a steerable catheter device comprises a shaft comprising a proximal portion, a distal portion, and a pull-wire lumen that extends at least partially through the proximal and distal portions. A pull wire extends through the pull-wire lumen and has a proximal end portion and a distal end portion, wherein the distal end portion of pull wire is fixed to the distal end portion of the shaft. An adjustment mechanism is operatively connected to the proximal end portion of the pull wire and configured to increase and decrease tension in the pull wire to adjust the curvature of the distal portion of the shaft. An axially non-compressible pull-wire sleeve extends co-axially through the pull-wire lumen and over the pull wire.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: October 6, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Sean Chow, Ronaldo C. Cayabyab
  • Patent number: 10786353
    Abstract: Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: September 29, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Netanel Benichou, Stanton J. Rowe, Sean Chow
  • Publication number: 20200085573
    Abstract: Anchor devices and methods used to secure a prosthetic valve to a native valve annulus are described. The anchor device can be a separate expandable element from the prosthetic valve that is first advanced to the annulus and deployed, after which an expandable prosthetic valve is advanced to within the annulus and deployed. The combination of the two elements can apply a clamping force to the valve leaflets which holds the prosthetic valve in place. The anchor device can have a lower or ventricular portion and an upper or atrial portion. The anchor device can include one or more leaflet clamping portions. One, two, or more upstanding vertical posts between the clamping portions can extend upward at the valve commissures and support the upper portion, which can include one or more structures for leak prevention.
    Type: Application
    Filed: November 21, 2019
    Publication date: March 19, 2020
    Inventors: Dustin P. Armer, Sean Chow, Jenny Nguyen, Emil Karapetian, Tri D. Tran
  • Publication number: 20190209322
    Abstract: Disclosed herein are devices for improving coaption of the mitral valve leaflets to reduce or eliminate mitral valve regurgitation. The devices may be used to perform mitral valve annuloplasty, or to serve as a docking station for a transcatheter prosthetic heart valve. The various embodiments of devices are configured for percutaneous and, in some cases, transvascular delivery. Delivery systems useful for routing the devices to the mitral valve are also disclosed, including catheters, balloons and/or mechanical expansion systems. The devices themselves include at least one tissue penetrating member. Methods of delivery include partially embedding the devices in the mitral valve annulus via at least one tissue penetrating member. Tissue penetrating members may be embedded into the tissue in a simultaneous or a nearly simultaneous fashion. Upon embedding, the devices employ various expansion and/or contraction features to adjust the mitral valve diameter.
    Type: Application
    Filed: March 19, 2019
    Publication date: July 11, 2019
    Inventors: David M. Taylor, Tri D. Tran, Sean Chow, David L. Hauser, Pui Tong Ho, Alexander H. Cooper
  • Publication number: 20190192296
    Abstract: A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.
    Type: Application
    Filed: January 21, 2019
    Publication date: June 27, 2019
    Inventors: Evan T. Schwartz, Sean Chow, Sandip Vasant Pawar, Darshin S. Patel, Chambory Chhe, Arpit Laddha, Ngoc Huong Thi Nguyen, Waina Michelle Chu, Yuanlong Du, Michael Bukin, Boaz Manash, Sara Haivatov, Tamir S. Levi
  • Patent number: 10278819
    Abstract: Disclosed herein are devices for improving coaption of the mitral valve leaflets to reduce or eliminate mitral valve regurgitation. The devices may be used to perform mitral valve annuloplasty, or to serve as a docking station for a transcatheter prosthetic heart valve. The various embodiments of devices are configured for percutaneous and, in some cases, transvascular delivery. Delivery systems useful for routing the devices to the mitral valve are also disclosed, including catheters, balloons and/or mechanical expansion systems. The devices themselves include at least one tissue penetrating member. Methods of delivery include partially embedding the devices in the mitral valve annulus via at least one tissue penetrating member. Tissue penetrating members may be embedded into the tissue in a simultaneous or a nearly simultaneous fashion. Upon embedding, the devices employ various expansion and/or contraction features to adjust the mitral valve diameter.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: May 7, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: David M. Taylor, Tri D. Tran, Sean Chow, David L. Hauser, Pui Tong Ho, Alexander H. Cooper
  • Publication number: 20190009061
    Abstract: In one representative embodiment, a steerable catheter device comprises a shaft comprising a proximal portion, a distal portion, and a pull-wire lumen that extends at least partially through the proximal and distal portions. A pull wire extends through the pull-wire lumen and has a proximal end portion and a distal end portion, wherein the distal end portion of pull wire is fixed to the distal end portion of the shaft. An adjustment mechanism is operatively connected to the proximal end portion of the pull wire and configured to increase and decrease tension in the pull wire to adjust the curvature of the distal portion of the shaft. An axially non-compressible pull-wire sleeve extends co-axially through the pull-wire lumen and over the pull wire.
    Type: Application
    Filed: September 11, 2018
    Publication date: January 10, 2019
    Inventors: Tri D. Tran, Sean Chow, Ronaldo C. Cayabyab
  • Patent number: 10076638
    Abstract: In one representative embodiment, a steerable catheter device comprises a shaft comprising a proximal portion, a distal portion, and a pull-wire lumen that extends at least partially through the proximal and distal portions. A pull wire extends through the pull-wire lumen and has a proximal end portion and a distal end portion, wherein the distal end portion of pull wire is fixed to the distal end portion of the shaft. An adjustment mechanism is operatively connected to the proximal end portion of the pull wire and configured to increase and decrease tension in the pull wire to adjust the curvature of the distal portion of the shaft. An axially non-compressible pull-wire sleeve extends co-axially through the pull-wire lumen and over the pull wire.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: September 18, 2018
    Assignee: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Sean Chow, Ronaldo C. Cayabyab
  • Publication number: 20180177592
    Abstract: Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed.
    Type: Application
    Filed: February 21, 2018
    Publication date: June 28, 2018
    Inventors: Netanel Benichou, Stanton J. Rowe, Sean Chow
  • Patent number: 9901446
    Abstract: Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: February 27, 2018
    Assignee: Edwards Lifesciences Corporation
    Inventors: Netanel Benichou, Stanton J. Rowe, Sean Chow
  • Publication number: 20180036124
    Abstract: A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion. The shaft is configured such that a fluid can flow through the lumen and the openings. The inner balloon has end portions and a center portion disposed between the end portions. The inner balloon is mounted on the distal end portion of the shaft and is in fluid communication with the openings of the shaft. When the inner balloon is inflated with the fluid, the end portions expand farther radially outwardly than the center portion. The outer balloon is mounted to the shaft and disposed over the inner balloon. The outer balloon is configured to fully expand after the inner balloon at least partially expands.
    Type: Application
    Filed: October 20, 2017
    Publication date: February 8, 2018
    Applicant: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Ronaldo C. Cayabyab, David J. Evans, Sean Chow, Christopher Chia, Tamir S. Levi
  • Patent number: 9795477
    Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: October 24, 2017
    Assignee: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Ronaldo C. Cayabyab, David J. Evans, Sean Chow, Christopher Chia
  • Publication number: 20160346084
    Abstract: Disclosed herein are devices for improving coaption of the mitral valve leaflets to reduce or eliminate mitral valve regurgitation. The devices may be used to perform mitral valve annuloplasty, or to serve as a docking station for a transcatheter prosthetic heart valve. The various embodiments of devices are configured for percutaneous and, in some cases, transvascular delivery. Delivery systems useful for routing the devices to the mitral valve are also disclosed, including catheters, balloons and/or mechanical expansion systems. The devices themselves include at least one tissue penetrating member. Methods of delivery include partially embedding the devices in the mitral valve annulus via at least one tissue penetrating member. Tissue penetrating members may be embedded into the tissue in a simultaneous or a nearly simultaneous fashion. Upon embedding, the devices employ various expansion and/or contraction features to adjust the mitral valve diameter.
    Type: Application
    Filed: May 27, 2016
    Publication date: December 1, 2016
    Applicant: Edwards Lifesciences Corporation
    Inventors: David M. Taylor, Tri D. Tran, Sean Chow, David L. Hauser, Pui Tong Ho, Alexander H. Cooper