Abstract: The present invention provides compositions and methods for improving the quality of life for a subject, particularly a child, diagnosed with autism spectrum disorder (ASD). In preferred embodiments, a supplement composition comprising natural or naturally-derived ingredients is delivered to a subject in the form of a chocolate bar or other candy alongside administration of an antiviral medication. Advantageously, the composition and methods can improve the immune health of the subject, along with other signs and symptoms associated with ASD, infections and other immunocompromising conditions.

Abstract: The subject invention provides microbe-based products, as well as their use to improve oil production and refining efficiency by, for example, remediating the disposable layers in oil tanks and other oil storage units. In preferred embodiments, the microbe-based products comprise biochemical-producing yeast and growth by-products thereof, such as, e.g., biosurfactants. The subject invention can be used to remediate rag layer and/or other dissolved solid layers that form in water-oil emulsions. Furthermore, the subject invention can be used for remediating solid impurities, such as sand, scale, rust and clay, in produced water, flow-back, brine, and/or fracking fluids.

Abstract: The subject invention provides topical therapeutic compositions and methods of their use for enhanced healing of wounds, including burns, and scars of the skin. Specifically, in one embodiment, the subject invention provides materials and methods for reducing the healing time of skin wounds and for reducing the appearance of scars. The subject invention utilizes topical compositions comprising microbial growth by-products and, optionally, a topically-acceptable carrier. In specific embodiments, the microbial growth by-products are biosurfactants.

Abstract: The subject invention provides microbe-based products, as well as their use, for enhancing aquaculture. In particular, the subject invention provides materials and methods for producing healthy and high quality farmed fish by applying yeast and/or bio surfactant-based compositions to a fish farm. In one embodiment, the subject invention improves the environment in which the fish are farmed. In another embodiment, the subject invention provides a highly nutritious fish feed, as well as methods of feeding fish at low cost.

Abstract: The subject invention provides yeast-based products, as well as their use to improve industrial production and performance by, for example, efficiently cleaning contaminating and/or fouling substances such as FOG, biofilm, paraffin, and/or asphaltenes from industrial equipment.

Abstract: Systems and apparatuses for producing microbe-based compositions that can be used in the oil and gas industry, environmental cleanup, as well as for other applications are provided. More specifically, apparatuses comprising two vessels for use in large-scale production of sophorolipids are provided. An apparatus can include a fermentation vessel and a collector vessel connected directly to the fermentation vessel.

Abstract: The subject invention provides microbe-based products, as well as their use to improve oil well production and increase the value of heavy crude oil. Specifically, the subject invention provides cultivated yeast products, which can be applied to oil and/or oil and gas production equipment to improve production and increase the economic value of heavy crude oil by, for example, upgrading heavy oils and/or converting heavy hydrocarbon substances, such as asphalts, asphaltenes, tars, bitumens and/or petcokes into lighter hydrocarbon substances.

Abstract: Compositions and methods are provided for enhancing plant immunity, health, growth and yields using a combination of microbes and/or their growth by-products. Specifically, the subject invention enhances plant health, growth and/or yields using a combination of a Trichoderma spp. fungus and a Bacillus spp. bacterium. Specifically, in one embodiment, the subject invention utilizes Trichoderma harzianum and Bacillus amyloliquefaciens.

Abstract: The present invention provides environmentally-friendly compositions and methods for degrading polymers used in fracking operations to enhance the recovery of oil and gas. Specifically, the compositions and methods utilized microorganisms and/or their growth by-products to degrade polymers, such as PGA, PLA and PAM, used in fracking wells.

Abstract: The invention provides materials and method for attracting and controlling plant-pathogenic nematodes. In specific embodiments, compositions are provided comprising Valerian root, which draws the nematodes away from plants, and/or a microbe-based composition comprising nematicidal microorganisms and/or their growth by-products, which control the nematodes upon contact. The compositions can be applied to a plants environment, including soil, to attract and control nematodes, and to reduce and/or prevent plant damage caused by nematodes.

Abstract: The subject invention provides compositions and methods for preserving food products. Specifically, the subject compositions and methods can be used to prolong the consumable life of food products, as well as to reduce and/or prevent spoilage and/or contamination by microbial agents. Preferably, the compositions comprise a blend of one or more glycolipids and one or more lipopeptides. Even more preferably, the compositions comprise sophorolipids and surfactin, lichenysin or another lipopeptide biosurfactant.

Abstract: The invention provides environmentally-friendly compositions and methods for reducing the viscosity of crude oil using microorganisms and/or biosurfactants produced by microorganisms.

Abstract: The present invention provides materials and methods for treating symptoms of neurological conditions. More specifically, the subject invention provides compositions and methods of their use for treating one or more symptoms and/or comorbidities of a neurological condition such as an infection, a neurodevelopmental disease, and/or a neurodegenerative disease. In preferred embodiments, the composition is administered to the subject via nasal administration.

Abstract: The subject invention provides microbe-based products, as well as their use to improve oil well production and increase the value of heavy crude oil. Specifically, the subject invention provides cultivated yeast products, which can be applied to oil and/or oil and gas production equipment to improve production and increase the economic value of heavy crude oil by, for example, upgrading heavy oils and/or converting heavy hydrocarbon substances, such as asphalts, asphaltenes, tars, bitumens and/or petcokes into lighter hydrocarbon substances.

Abstract: The subject invention provides systems and methods for classifying a microbiome at a geographic site where agricultural activity is, or will be, conducted in order to improve and/or promote agricultural productivity at the site. The subject invention utilizes a large sample set of diverse DNA sequencing input data collected from soil, plant, water and/or air samples, as well as environmental information, to determine relationships between environmental factors and the identities, quantities and distributions of microbial species, taxonomies, and/or groupings thereof, at a chosen site. Machine learning and/or artificial intelligence classifier tools use this information to generate various output data, such as, for example, recommendations for customized soil and/or crop treatment compositions, irrigation practices, and/or other agricultural activity, to enhance plant health and crop productivity at the site.

Abstract: The subject invention provides multi-functional biochemical compositions, as well as their use in enhancing oil recovery from an oil-bearing subterranean formation. Advantageously, the compositions and methods of the subject invention are operationally-friendly, cost-effective, and environmentally-friendly. More specifically, in preferred embodiments, the subject invention provides a multi-functional composition for enhanced oil recovery (EOR) comprising one or more surfactants, one or more chelating agents, and one or more solvents.

Abstract: The subject invention provides improved methods for producing biosurfactants using bacteria not previously known to produce both glycolipids and lipopeptides. In particular, Bacillus amyloliquefaciens can be cultivated under specially-tailored conditions such that the bacteria produces both glycolipids resembling mannosylerythritol lipids (MEL), and lipopeptides. A bacterial culture composition is also provided, comprising bacterial cells, liquid growth medium and a high concentration of one or more growth by-products, such as MEL-like glycolipids and/or lipopeptides.

Abstract: Methods are provided for enhanced production of one or more microbial biopolymers, the methods comprising co-cultivating Stigmatella aurantiaca and Acinetobacter venetianus. In certain embodiments, the one or more biopolymers are emulsan. In certain embodiments, other microbial growth by-products are produced, such as biosurfactants. Microbe-based products produced according to the subject methods are also provided, as well as their uses in, for example, oil and gas recovery, agriculture, and health care.

Abstract: The subject invention relates to the production and use of entomopathogenic fungi for the control of arthropod pests. Specifically, the subject invention provides methods for producing Metarhizium anisopliae and Beauveria bassiana, as well as methods of their use, as biopesticidal compositions. Compositions are also provided for controlling arthropod pests, comprising one or more entomopathogenic fungi, a chitinase inducer, diatomaceous earth, and an anticoagulant.

Abstract: Methods are provided for cultivating fungi for scaled-up production of microbe-based products. Specifically, cultures of fungi, such as, e.g., Pisolithus tinctorius, are grown by aerobic submerged fermentation in liquid medium containing a particulate anchoring carrier to increase mycelial biomass.