Abstract: A system and method are provided for assessing a radiation therapy plan to be implemented on a particular radiation therapy system that includes a multi-leaf collimator (MLC). The method includes receiving a radiation therapy plan and calculating at least one metric indicating transmission characteristics of a beam delivered using the particular radiation therapy system to perform the radiation therapy plan using a model of the MLC having a plurality of zones, wherein each zone is classified based on the transmission characteristics. The method also includes evaluating the at least one metric against a tolerance for variation between the radiation therapy plan and an implementation of the radiation therapy plan on the particular radiation therapy system and generating an alert indicating that the at least one metric is outside the tolerance.

Abstract: A radiation therapy planning system (10) includes an isodose line unit (36), a region of interest unit (52), and an optimization unit (58). The isodose line unit (36) receives isodose lines planned for a volume of a subject. The region of interest unit (52) defines at least one isodose region of interest based on the received isodose lines. The optimization unit (58) generates an optimized radiation therapy plan based on the at least one defined isodose region of interest and at least one dose objective for the defined region of interest.

Abstract: A system for visualizing and modifying the thickness of a compensator for radiation therapy in the context of a desired target and dose coverage thereof includes planar slice image generation module, a visualization unit and an adjustment module. The planar slice image generation module generates a series of planar slice images from a patient image data set disposed with one axis parallel to a radiation beam and one axis perpendicular to the radiation beam. The visualization unit graphically depicts a compensator thickness profile, a target of interest, and/or a dose representation on at least one of the series of planar slice images all in the same plane lying in a beam's longitudinal direction. The adjustment module receives user input of an adjustment of at least one compensator thickness value via a manipulation of the graphical depiction thereof.

Abstract: An imaging system (10) generates a layered reconstructed radiograph (LRR) (66) of a subject. The system (10) takes as input a three-dimensional (3D) or higher dimensional data set (68) of the object, e.g. data produced by an image scanner (12). At least one processor (32) is programmed to define a set of two-dimensional (2D) projection images and associated view windows (60, 62, 64) corresponding to a set of voxel value (tissue) types with corresponding voxel value specification (50); determine the contribution of each processed voxel along each of a plurality of rays (72) through the 3D data set (68) to one of the predetermined voxel value (tissue) types in accordance with each voxel value with respect to the voxel value selection specification (50); and concurrently generate a 2D projection image corresponding to each of the voxel value specifications and related image view windows (60, 62, 64) based on the processed voxel values satisfying the corresponding voxel value specification (50).

Abstract: A radiation therapy planning system (10) includes an isodose line unit (36), a region of interest unit (52), and an optimization unit (58). The isodose line unit (36) receives isodose lines planned for a volume of a subject. The region of interest unit (52) defines at least one isodose region of interest based on the received isodose lines. The optimization unit (58) generates an optimized radiation therapy plan based on the at least one defined isodose region of interest and at least one dose objective for the defined region of interest.

Abstract: A system (10) for visualizing and modifying the thickness of a compensator (26) for radiation therapy in the context of a desired target and dose coverage thereof includes planar slice image generation module (40), a visualization unit (42) and an adjustment module (44). The planar slice image generation module (40) generates a series of planar slice images (24) from a patient image data set (14) disposed with one axis parallel to a radiation beam and one axis perpendicular to the radiation beam (22). The visualization unit (42) graphically depicts a compensator thickness profile (26), a target of interest (28), and/or a dose representation on at least one of the series of planar slice images (24) all in the same plane lying in a beam's longitudinal direction. The adjustment module (44) receives user input of an adjustment of at least one compensator thickness value via a manipulation of the graphical depiction thereof.

Abstract: An imaging system (10) generates a layered reconstructed radiograph (LRR) (66) of a subject. The system (10) takes as input a three-dimensional (3D) or higher dimensional data set (68) of the object, e.g. data produced by an image scanner (12). At least one processor (32) is programmed to define a set of two-dimensional (2D) projection images and associated view windows (60, 62, 64) corresponding to a set of voxel value (tissue) types with corresponding voxel value specification (50); determine the contribution of each processed voxel along each of a plurality of rays (72) through the 3D data set (68) to one of the predetermined voxel value (tissue) types in accordance with each voxel value with respect to the voxel value selection specification (50); and concurrently generate a 2D projection image corresponding to each of the voxel value specifications and related image view windows (60, 62, 64) based on the processed voxel values satisfying the corresponding voxel value specification (50).