Patents by Inventor Sean Grant Buchanan

Sean Grant Buchanan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Crystals and structures of spleen tyrosine kinase SYKKD

Publication number: 20040253178

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of SYKKD and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of SYKKD, and compounds and compositions that affect SYK activity.

Type: Application

Filed: December 17, 2003

Publication date: December 16, 2004

Inventors: Shane Atwell, Jorg Hendle, Sean Grant Buchanan, Ingeborg Feil, Marijane Russell, John Badger, Masaki Tomimoto, Michael J. Sauder
Crystals and structures of epidermal growth factor receptor kinase domain

Publication number: 20040248800

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of EGFRKD complexed with AMP-PNP and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of EGFRKD, and compounds and compositions that affect EGFR activity.

Type: Application

Filed: March 16, 2004

Publication date: December 9, 2004

Inventors: Shane Atwell, Sean Grant Buchanan
Crystals and structures of PAK4KD kinase PAK4KD

Publication number: 20030229453

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of PAK4KD kinase, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of PAK4KD, PAK4KD crystals, and compounds and compositions that affect PAK4KD activity.

Type: Application

Filed: April 2, 2003

Publication date: December 11, 2003

Inventors: Stephen Suresh Antonysamy, Ingeborg K. Feil, Sean Grant Buchanan, Kai W. Post, Yi Liu, David Lorber
Crystals and structures of MST3

Publication number: 20030225527

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of MST3KD and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of MST3KD, and compounds and compositions that affect MST3KD activity.

Type: Application

Filed: March 12, 2003

Publication date: December 4, 2003

Inventors: Stephen Suresh Antonysamy, Ingeborg Feil, Sean Grant Buchanan, Jian Xu
Crystals and structures of a flavin mononucleotide binding protein (FMNBP)

Publication number: 20030187220

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of putative flavin oxidoreductase, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of FMNBP, and compounds and compositions that affect FMNBP activity.

Type: Application

Filed: November 26, 2002

Publication date: October 2, 2003

Inventors: Frances Park, Ketan S. Gajiwala, Sean Grant Buchanan, J. Michael Sauder
Crystals and structures of ATP phosphoribosyltransferase

Publication number: 20030171904

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of ATP phosphoribosyltransferase, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of ATP-PRT, and compounds and compositions that affect ATP-PRT activity.

Type: Application

Filed: December 12, 2002

Publication date: September 11, 2003

Inventors: Hal Lewis, J. Michael Sauder, Sean Grant Buchanan
Crystals and structures of YiiM proteins

Publication number: 20030171549

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of YiiM family members, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of YiiM family members, and compounds and compositions that affect YiiM family members activity.

Type: Application

Filed: November 8, 2002

Publication date: September 11, 2003

Inventors: Frances Park, Ketan S. Gajiwala, Sean Grant Buchanan, J. Michael Sauder
Crystals and structures of members of the E. coli comA and yddB protein families (ComA)

Publication number: 20030158384

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of ComA proteins, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of ComA, and compounds and compositions that affect ComA activity.

Type: Application

Filed: November 8, 2002

Publication date: August 21, 2003

Inventors: Gordon V. Louie, Ketan S. Gajiwala, Sean Grant Buchanan
Crystals and structures of a bacterial nucleic acid binding protein

Publication number: 20030129656

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of BNAB protein, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of BNAB, and compounds and compositions that affect BNAB activity.

Type: Application

Filed: November 1, 2002

Publication date: July 10, 2003

Inventors: Frances Park, Ketan S. Gajiwala, Sean Grant Buchanan
Crystals and structures of ArnB aminotransferases

Publication number: 20030105010

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of ArnB amino transferases, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of ArnB, and compounds and compositions that affect ArnB activity.

Type: Application

Filed: July 12, 2002

Publication date: June 5, 2003

Inventors: Janet Newman, John Badger, Brian Noland, Jorg Hendle, Sean Grant Buchanan
Crystals and structures of perosamine synthase homologs

Publication number: 20030101005

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of PLP-dependent enzyme, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of PSH, and compounds and compositions that affect PSH activity.

Type: Application

Filed: July 12, 2002

Publication date: May 29, 2003

Inventors: Hans-Joachim Muller-Dieckmann, John Badger, Brian Noland, Jorg Hendle, Sean Grant Buchanan
Crystals and structures of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase MECPS

Publication number: 20030073134

Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of MECPS, and compounds and compositions that affect MECPS activity.

Type: Application

Filed: June 17, 2002

Publication date: April 17, 2003

Inventors: Gordon V. Louie, Sean Grant Buchanan, Ketan S. Gajiwala, J. Michael Sauder