Abstract: Disclosed herein are methods of identifying a test compound as agonists or antagonists of Akt activity. The methods involve contacting the test compound with a cell that expresses a biosensor comprising a FOXO1 or HDHB polypeptide and a fluorescent protein and locating the biosensor within the cell. Locating the biosensor in the nucleus relative to the cytoplasm is an indication that the test compound has an effect upon Akt activity.

Abstract: Telephony system includes base station and handsets. Base station includes radio transceiver for transmitting and receiving cordless telephone radio signals, and network connection for transmitting and receiving voice over internet protocol (VoIP) communications. Each handset includes a handset radio transceiver for transmitting and receiving cordless telephone radio signals. Base station converts received VoIP communications to cordless telephone radio signals and transmits converted cordless telephone radio signals through the base station radio transceiver. The base station includes navigation keys utilized as shortcut keys to base station features. The base station includes a “SORT” soft key and sorts call log records alphabetically when key pressed. The base station enables searching of call log records by entering name of caller.