Patents by Inventor Sean J. Pittock

Sean J. Pittock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MATERIALS AND METHODS FOR EVALUATING AND TREATING NEUROMYELITIS OPTICA (NMO)
    Publication number: 20240060975
    Abstract: The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases.
    Type: Application
    Filed: May 5, 2023
    Publication date: February 22, 2024
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Sean J. Pittock, Shannon Hinson
  • ASSESSING AND TREATING AUTOIMMUNE ATAXIA
    Publication number: 20230039907
    Abstract: Methods and materials herein are useful for assessing and/or treating autoimmune ataxias associated with septin-specific autoantibodies septin-5-specific autoantibodies For example, septin-5 polypeptides are provided as well as methods for using septin-5 polypeptides to detect septin-5-specific autoantibodies and/or to treat a mammal having an autoimmune ataxia.
    Type: Application
    Filed: September 30, 2022
    Publication date: February 9, 2023
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Josephe A. HONORAT, Andrew McKeon, Sean J. Pittock, Vanda A. Lennon
  • Assessing and treating autoimmune ataxia
    Patent number: 11493513
    Abstract: Methods and materials herein are useful for assessing and/or treating autoimmune ataxias associated with septin-specific autoantibodies (e.g., septin-5-specific autoantibodies). For example, septin-5 polypeptides are provided as well as methods for using septin-5 polypeptides to detect septin-5-specific autoantibodies and/or to treat a mammal having an autoimmune ataxia.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: November 8, 2022
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Josephe A. Honorat, Andrew McKeon, Sean J. Pittock, Vanda A. Lennon
  • MATERIALS AND METHODS FOR EVALUATING AND TREATING NEUROMYELITIS OPTICA (NMO)
    Publication number: 20220196652
    Abstract: The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases.
    Type: Application
    Filed: December 29, 2021
    Publication date: June 23, 2022
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Sean J. Pittock, Shannon Hinson
  • AUTOANTIBODIES AS BIOMARKER OF PARANEOPLASTIC ENCEPHALITIS ASSOCIATED WITH TESTICULAR CANCER
    Publication number: 20220196662
    Abstract: This disclosure describes methods and compositions for detecting the presence of a Kelch-like protein 11 autoantibody in a biological sample. Also provided are methods of treating subjects with testicular cancer or a premalignant condition and paraneoplastic encephalomyelitis.
    Type: Application
    Filed: March 13, 2020
    Publication date: June 23, 2022
    Inventors: Joseph L. DeRisi, Michael R. Wilson, Caleigh Mandel-Brehm, Brian O'Donovan, Sean J. Pittock, Divyanshu Dubey, Thomas J. Kryzer, Vanda A. Lennon, Andrew McKeon
  • ASSESSING AND TREATING GERM CELL TUMORS AND PARANEOPLASTIC AUTOIMMUNITY
    Publication number: 20220120744
    Abstract: Materials and methods for detecting LUZP4 IgG in a mammal, as well as materials and methods for using LUZP4 as a serological biomarker of germ cell tumors and paraneoplastic autoimmunity, are provided herein. Also provided herein are materials and methods for treating a mammal identified as having anti-LUZP4 autoantibodies.
    Type: Application
    Filed: July 24, 2020
    Publication date: April 21, 2022
    Inventors: Vanda A. Lennon, Andrew McKeon, Thomas J. Kryzer, Sean J. Pittock, Divyanshu Dubey
  • ASSESSING AND TREATING AUTOIMMUNE ATAXIA
    Publication number: 20210311047
    Abstract: Methods and materials herein are useful for assessing and/or treating autoimmune ataxics associated with septin-specific autoantibodies (e.g., septin-5-specific autoantibodies). For example, septin-5 polypeptides are provided as well as methods for using septin-5 polypeptides to detect septin-5-specific autoantibodies and/or to treat a mammal having an autoimmune ataxia.
    Type: Application
    Filed: May 21, 2019
    Publication date: October 7, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Josephe A. HONORAT, Andrew McKeon, Sean J. Pittock, Vanda A, Lennon
  • Materials and methods for evaluating and treating cancer
    Patent number: 11061027
    Abstract: This document provides methods and materials for detecting PCA-2-specific autoantibodies, which can be associated with paraneoplastic neurological disorders and cancers associated with PCA-2-specific autoantibodies.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: July 13, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Sean J. Pittock, Thomas J. Kryzer, Avi Gadoth, Andrew McKeon, Vanda A. Lennon, James P. Fryer
  • MATERIALS AND METHODS FOR EVALUATING AND TREATING NEUROMYELITIS OPTICA (NMO)
    Publication number: 20200393462
    Abstract: The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases.
    Type: Application
    Filed: July 1, 2020
    Publication date: December 17, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Sean J. Pittock, Shannon Hinson
  • MATERIALS AND METHODS FOR EVALUATING AND TREATING CANCER
    Publication number: 20200041505
    Abstract: This document provides methods and materials for detecting PCA-2-specific autoantibodies, which can be associated with paraneoplastic neurological disorders and cancers associated with PCA-2-specific autoantibodies.
    Type: Application
    Filed: September 12, 2017
    Publication date: February 6, 2020
    Inventors: Sean J. Pittock, Thomas J. Kryzer, Avi Gadoth, Andrew McKeon, Vanda A. Lennon, James P. Fryer
  • MATERIALS AND METHODS FOR EVALUATING AND TREATING NEUROMYELITIS OPTICA (NMO)
    Publication number: 20190242892
    Abstract: The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases.
    Type: Application
    Filed: December 12, 2018
    Publication date: August 8, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Sean J. Pittock, Shannon Hinson
  • MATERIALS AND METHODS FOR EVALUATING AND TREATING NEUROMYELITIS OPTICA (NMO)
    Publication number: 20180246093
    Abstract: The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases.
    Type: Application
    Filed: January 4, 2018
    Publication date: August 30, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Sean J. Pittock, Shannon Hinson
  • Methods for treating neuromyelitis optica (NMO) by administration of eculizumab to an individual that is aquaporin-4 (AQP4)-IgG autoantibody positive
    Patent number: 9891219
    Abstract: The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: February 13, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Shannon Hinson, Sean J. Pittock
  • MATERIALS AND METHODS FOR EVALUATING AND TREATING NEUROMYELITIS OPTICA (NMO)
    Publication number: 20150104813
    Abstract: The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases.
    Type: Application
    Filed: August 27, 2014
    Publication date: April 16, 2015
    Inventors: Vanda A. Lennon, Shannon Hinson, Sean J. Pittock
  • PERIPHERIN-SPECIFIC AUTOANTIBODIES AS A MARKER FOR NEUROLOGICAL AND ENDOCRINOLOGICAL DISEASE
    Publication number: 20140377883
    Abstract: The present invention provides for methods and materials for detecting a peripherin-specific autoantibody, which can be associated with neurological and endocrinological disease.
    Type: Application
    Filed: September 8, 2014
    Publication date: December 25, 2014
    Inventors: Vanda A. Lennon, Jayne Chamberlain-Banoub, Thomas J. Kryzer, Sean J. Pittock, Anna Maria Oprescu
  • Neuromyelitis optica autoantibodies as a marker for neoplasia
    Patent number: 8889102
    Abstract: The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO).
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: November 18, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Sean J. Pittock
  • METHODS AND COMPOSITIONS FOR DETECTING THE PRESENCE OF ONE OR MORE AUTOANTIBODIES
    Publication number: 20140315225
    Abstract: This disclosure describes methods and compositions for immunohistochemically detecting the presence of a SRP autoantibody in a biological sample.
    Type: Application
    Filed: September 14, 2012
    Publication date: October 23, 2014
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Vanda A. Lennon, Thomas J. Kryzer, James P. Fryer, Sean J. Pittock, Metha Apiwattanakul
  • MATERIALS AND METHODS FOR EVALUATING AND TREATING NEUROMYELITIS OPTICA (NMO)
    Publication number: 20140030262
    Abstract: The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases.
    Type: Application
    Filed: October 2, 2013
    Publication date: January 30, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Shannon Hinson, Sean J. Pittock
  • PERIPHERIN-SPECIFIC AUTOANTIBODIES AS A MARKER FOR NEUROLOGICAL AND ENDOCRINOLOGICAL DISEASE
    Publication number: 20130023484
    Abstract: The present invention provides for methods and materials for detecting a peripherin-specific autoantibody, which can be associated with neurological and endocrinological disease.
    Type: Application
    Filed: January 4, 2011
    Publication date: January 24, 2013
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Vanda A. Lennon, Jayne Chamberlain, Thomas J. Kryzer, Sean J. Pittock, Anna Maria Oprescu
  • NEUROMYELITIS OPTICA AUTOANTIBODIES AS A MARKER FOR NEOPLASIA
    Publication number: 20100226860
    Abstract: The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO).
    Type: Application
    Filed: September 19, 2008
    Publication date: September 9, 2010
    Inventors: Vanda A. Lennon, Sean J. Pittock